DRUG BINDING INTERFACES MAPPED TO 'CIA'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 1UDU_A_CIAA1003 | 1udu | CIA DB00820(Tadalafil) | Homo sapiens | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE | PF00233(PDEase_I) | 11 | TYR A 612SER A 663ILE A 778VAL A 782ALA A 783PHE A 786LEU A 804ILE A 813MET A 816GLN A 817PHE A 820 | CIA A1003 |
| 1UDU_B_CIAB2003 | 1udu | CIA DB00820(Tadalafil) | Homo sapiens | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE | no annotation | 12 | TYR B 612ALA B 767ILE B 768GLN B 775ILE B 778VAL B 782ALA B 783PHE B 786LEU B 804MET B 816GLN B 817PHE B 820 | CIA B2003 |
| 1XOZ_A_CIAA501 | 1xoz | CIA DB00820(Tadalafil) | Homo sapiens | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE | PF00233(PDEase_I) | 12 | TYR A 612ALA A 767ILE A 768GLN A 775ILE A 778VAL A 782PHE A 786LEU A 804ILE A 813MET A 816GLN A 817PHE A 820 | CIA A 501 |