DRUG BINDING INTERFACES MAPPED TO 'BAX'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1UWH_A_BAXA1723	1uwh	BAX DB00398 (Sorafenib)	Homo sapiens	B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE	PF07714 (Pkinase_Tyr)	18	ILE A 462 VAL A 470 ALA A 480 GLU A 500 VAL A 503 LEU A 504 ILE A 512 LEU A 513 THR A 528 TRP A 530 CYS A 531 LEU A 566 ILE A 571 HIS A 573 PHE A 582 GLY A 592 ASP A 593 PHE A 594	BAX A1723
1UWH_B_BAXB1723	1uwh	BAX DB00398 (Sorafenib)	Homo sapiens	B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE	no annotation	18	ILE B 462 VAL B 470 ALA B 480 LYS B 482 GLU B 500 VAL B 503 LEU B 504 ILE B 512 LEU B 513 THR B 528 TRP B 530 CYS B 531 LEU B 566 ILE B 571 HIS B 573 PHE B 582 GLY B 592 ASP B 593	BAX B1723
1UWJ_A_BAXA1723	1uwj	BAX DB00398 (Sorafenib)	Homo sapiens	B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE	PF07714 (Pkinase_Tyr)	19	ILE A 462 VAL A 470 ALA A 480 LYS A 482 GLU A 500 LEU A 504 THR A 507 ILE A 512 LEU A 513 THR A 528 TRP A 530 CYS A 531 LEU A 566 ILE A 571 HIS A 573 GLY A 592 ASP A 593 PHE A 594 SER A 601	BAX A1723
1UWJ_B_BAXB1723	1uwj	BAX DB00398 (Sorafenib)	Homo sapiens	B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE	no annotation	15	ILE B 462 VAL B 470 ALA B 480 GLU B 500 ILE B 512 LEU B 513 THR B 528 TRP B 530 CYS B 531 LEU B 566 HIS B 573 GLY B 592 ASP B 593 PHE B 594 LYS B 600	BAX B1723
3GCS_A_BAXA401	3gcs	BAX DB00398 (Sorafenib)	Homo sapiens	MITOGEN-ACTIVATED PROTEIN KINASE 14	PF00069 (Pkinase)	18	VAL A 38 ALA A 51 ARG A 70 GLU A 71 LEU A 74 LEU A 75 MET A 78 VAL A 83 ILE A 84 THR A 106 LEU A 108 MET A 109 ILE A 141 ILE A 146 HIS A 148 ILE A 166 LEU A 167 ASP A 168	BAX A 401
3HEG_A_BAXA1	3heg	BAX DB00398 (Sorafenib)	Homo sapiens	MITOGEN-ACTIVATED PROTEIN KINASE 14	PF00069 (Pkinase)	18	VAL A 30 VAL A 38 ALA A 51 LYS A 53 GLU A 71 LEU A 74 LEU A 75 MET A 78 VAL A 83 ILE A 84 THR A 106 MET A 109 ILE A 141 ILE A 146 HIS A 148 ILE A 166 LEU A 167 ASP A 168	BAX A 1
3RGF_A_BAXA465	3rgf	BAX DB00398 (Sorafenib)	Homo sapiens	CYCLIN-DEPENDENT KINASE 8	PF00069 (Pkinase)	19	VAL A 35 ALA A 50 LYS A 52 GLU A 66 LEU A 70 LEU A 73 VAL A 78 ILE A 79 PHE A 97 TYR A 99 ALA A 100 LEU A 142 VAL A 147 HIS A 149 LEU A 158 ALA A 172 ASP A 173 MET A 174 PHE A 176	BAX A 465
3WZE_A_BAXA1201	3wze	BAX DB00398 (Sorafenib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	20	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 LEU A 889 ILE A 892 VAL A 898 VAL A 899 VAL A 916 PHE A 918 CYS A 919 GLY A 922 LEU A1019 HIS A1026 LEU A1035 ILE A1044 CYS A1045 ASP A1046 PHE A1047	BAX A1201
4ASD_A_BAXA1500	4asd	BAX DB00398 (Sorafenib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	18	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 LEU A 889 ILE A 892 VAL A 899 VAL A 916 PHE A 918 CYS A 919 GLY A 922 LEU A1019 HIS A1026 LEU A1035 ILE A1044 CYS A1045 PHE A1047	BAX A1500
5HI2_A_BAXA801	5hi2	BAX DB00398 (Sorafenib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE B-RAF	PF07714 (Pkinase_Tyr)	20	ILE A 463 VAL A 471 ALA A 481 LYS A 483 GLU A 501 VAL A 504 LEU A 505 ILE A 513 LEU A 514 THR A 529 TRP A 531 CYS A 532 LEU A 567 ILE A 572 HIS A 574 PHE A 583 ILE A 592 GLY A 593 ASP A 594 PHE A 595	BAX A 801

[["1UWH_A_BAXA1723","1uwh","BAX","DB00398(Sorafenib)","Homo sapiens","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","PF07714(Pkinase_Tyr)",18,"ILE A 462;VAL A 470;ALA A 480;GLU A 500;VAL A 503;LEU A 504;ILE A 512;LEU A 513;THR A 528;TRP A 530;CYS A 531;LEU A 566;ILE A 571;HIS A 573;PHE A 582;GLY A 592;ASP A 593;PHE A 594","BAX A1723\r"],["1UWH_B_BAXB1723","1uwh","BAX","DB00398(Sorafenib)","Homo sapiens","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","no annotation",18,"ILE B 462;VAL B 470;ALA B 480;LYS B 482;GLU B 500;VAL B 503;LEU B 504;ILE B 512;LEU B 513;THR B 528;TRP B 530;CYS B 531;LEU B 566;ILE B 571;HIS B 573;PHE B 582;GLY B 592;ASP B 593","BAX B1723\r"],["1UWJ_A_BAXA1723","1uwj","BAX","DB00398(Sorafenib)","Homo sapiens","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","PF07714(Pkinase_Tyr)",19,"ILE A 462;VAL A 470;ALA A 480;LYS A 482;GLU A 500;LEU A 504;THR A 507;ILE A 512;LEU A 513;THR A 528;TRP A 530;CYS A 531;LEU A 566;ILE A 571;HIS A 573;GLY A 592;ASP A 593;PHE A 594;SER A 601","BAX A1723\r"],["1UWJ_B_BAXB1723","1uwj","BAX","DB00398(Sorafenib)","Homo sapiens","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","no annotation",15,"ILE B 462;VAL B 470;ALA B 480;GLU B 500;ILE B 512;LEU B 513;THR B 528;TRP B 530;CYS B 531;LEU B 566;HIS B 573;GLY B 592;ASP B 593;PHE B 594;LYS B 600","BAX B1723\r"],["3GCS_A_BAXA401","3gcs","BAX","DB00398(Sorafenib)","Homo sapiens","MITOGEN-ACTIVATED PROTEIN KINASE 14","PF00069(Pkinase)",18,"VAL A  38;ALA A  51;ARG A  70;GLU A  71;LEU A  74;LEU A  75;MET A  78;VAL A  83;ILE A  84;THR A 106;LEU A 108;MET A 109;ILE A 141;ILE A 146;HIS A 148;ILE A 166;LEU A 167;ASP A 168","BAX A 401\r"],["3HEG_A_BAXA1","3heg","BAX","DB00398(Sorafenib)","Homo sapiens","MITOGEN-ACTIVATED PROTEIN KINASE 14","PF00069(Pkinase)",18,"VAL A  30;VAL A  38;ALA A  51;LYS A  53;GLU A  71;LEU A  74;LEU A  75;MET A  78;VAL A  83;ILE A  84;THR A 106;MET A 109;ILE A 141;ILE A 146;HIS A 148;ILE A 166;LEU A 167;ASP A 168","BAX A   1\r"],["3RGF_A_BAXA465","3rgf","BAX","DB00398(Sorafenib)","Homo sapiens","CYCLIN-DEPENDENT KINASE 8","PF00069(Pkinase)",19,"VAL A  35;ALA A  50;LYS A  52;GLU A  66;LEU A  70;LEU A  73;VAL A  78;ILE A  79;PHE A  97;TYR A  99;ALA A 100;LEU A 142;VAL A 147;HIS A 149;LEU A 158;ALA A 172;ASP A 173;MET A 174;PHE A 176","BAX A 465\r"],["3WZE_A_BAXA1201","3wze","BAX","DB00398(Sorafenib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",20,"LEU A 840;VAL A 848;ALA A 866;LYS A 868;GLU A 885;LEU A 889;ILE A 892;VAL A 898;VAL A 899;VAL A 916;PHE A 918;CYS A 919;GLY A 922;LEU A1019;HIS A1026;LEU A1035;ILE A1044;CYS A1045;ASP A1046;PHE A1047","BAX A1201\r"],["4ASD_A_BAXA1500","4asd","BAX","DB00398(Sorafenib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",18,"LEU A 840;VAL A 848;ALA A 866;LYS A 868;GLU A 885;LEU A 889;ILE A 892;VAL A 899;VAL A 916;PHE A 918;CYS A 919;GLY A 922;LEU A1019;HIS A1026;LEU A1035;ILE A1044;CYS A1045;PHE A1047","BAX A1500\r"],["5HI2_A_BAXA801","5hi2","BAX","DB00398(Sorafenib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","PF07714(Pkinase_Tyr)",20,"ILE A 463;VAL A 471;ALA A 481;LYS A 483;GLU A 501;VAL A 504;LEU A 505;ILE A 513;LEU A 514;THR A 529;TRP A 531;CYS A 532;LEU A 567;ILE A 572;HIS A 574;PHE A 583;ILE A 592;GLY A 593;ASP A 594;PHE A 595","BAX A 801\r"]]