DRUG BINDING INTERFACES MAPPED TO 'AXI'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

Filter list by:

DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
4AG8_A_AXIA2000	4ag8	AXI DB06626 (Axitinib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	14	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 VAL A 899 VAL A 914 VAL A 916 PHE A 918 CYS A 919 GLY A 922 LEU A1035 CYS A1045 PHE A1047	AXI A2000
4AGC_A_AXIA2000	4agc	AXI DB06626 (Axitinib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	14	ILE A 804 LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 LEU A 889 VAL A 899 VAL A 916 CYS A 919 GLY A 922 LEU A1035 CYS A1045 PHE A1047	AXI A2000
4TWP_A_AXIA601	4twp	AXI DB06626 (Axitinib)	Homo sapiens	TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	12	LEU A 248 TYR A 253 VAL A 256 ALA A 269 LYS A 271 PHE A 317 MET A 318 GLY A 321 ASN A 368 LEU A 370 ALA A 380 ASP A 381	AXI A 601
4TWP_B_AXIB601	4twp	AXI DB06626 (Axitinib)	Homo sapiens	TYROSINE-PROTEIN KINASE ABL1	no annotation	12	LEU B 248 TYR B 253 VAL B 256 ALA B 269 LYS B 271 PHE B 317 MET B 318 GLY B 321 ASN B 368 LEU B 370 ALA B 380 ASP B 381	AXI B 601
4WA9_A_AXIA9000	4wa9	AXI DB06626 (Axitinib)	Homo sapiens	TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	11	LEU A 248 TYR A 253 ALA A 269 LYS A 271 THR A 315 MET A 318 GLY A 321 ASN A 368 LEU A 370 ALA A 380 PHE A 382	AXI A9000
4WA9_B_AXIB9000	4wa9	AXI DB06626 (Axitinib)	Homo sapiens	TYROSINE-PROTEIN KINASE ABL1	no annotation	12	TYR B 253 VAL B 256 ALA B 269 LYS B 271 THR B 315 PHE B 317 MET B 318 GLY B 321 ASN B 368 LEU B 370 ALA B 380 PHE B 382	AXI B9000

[["4AG8_A_AXIA2000","4ag8","AXI","DB06626(Axitinib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",14,"LEU A 840;VAL A 848;ALA A 866;LYS A 868;GLU A 885;VAL A 899;VAL A 914;VAL A 916;PHE A 918;CYS A 919;GLY A 922;LEU A1035;CYS A1045;PHE A1047","AXI A2000\r"],["4AGC_A_AXIA2000","4agc","AXI","DB06626(Axitinib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",14,"ILE A 804;LEU A 840;VAL A 848;ALA A 866;LYS A 868;GLU A 885;LEU A 889;VAL A 899;VAL A 916;CYS A 919;GLY A 922;LEU A1035;CYS A1045;PHE A1047","AXI A2000\r"],["4TWP_A_AXIA601","4twp","AXI","DB06626(Axitinib)","Homo sapiens","TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",12,"LEU A 248;TYR A 253;VAL A 256;ALA A 269;LYS A 271;PHE A 317;MET A 318;GLY A 321;ASN A 368;LEU A 370;ALA A 380;ASP A 381","AXI A 601\r"],["4TWP_B_AXIB601","4twp","AXI","DB06626(Axitinib)","Homo sapiens","TYROSINE-PROTEIN KINASE ABL1","no annotation",12,"LEU B 248;TYR B 253;VAL B 256;ALA B 269;LYS B 271;PHE B 317;MET B 318;GLY B 321;ASN B 368;LEU B 370;ALA B 380;ASP B 381","AXI B 601\r"],["4WA9_A_AXIA9000","4wa9","AXI","DB06626(Axitinib)","Homo sapiens","TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",11,"LEU A 248;TYR A 253;ALA A 269;LYS A 271;THR A 315;MET A 318;GLY A 321;ASN A 368;LEU A 370;ALA A 380;PHE A 382","AXI A9000\r"],["4WA9_B_AXIB9000","4wa9","AXI","DB06626(Axitinib)","Homo sapiens","TYROSINE-PROTEIN KINASE ABL1","no annotation",12,"TYR B 253;VAL B 256;ALA B 269;LYS B 271;THR B 315;PHE B 317;MET B 318;GLY B 321;ASN B 368;LEU B 370;ALA B 380;PHE B 382","AXI B9000\r"]]