DRUG BINDING INTERFACES MAPPED TO '8PR'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
3V5W_A_8PRA701 | 3v5w | 8PR DB00715(Paroxetine) | Homo sapiens | G-PROTEIN COUPLEDRECEPTOR KINASE 2 | PF00069(Pkinase)PF00169(PH)PF00615(RGS) | 15 | ILE A 197GLY A 200GLY A 203VAL A 205ALA A 218LYS A 220LEU A 222VAL A 255LEU A 271MET A 274ASP A 278LEU A 324SER A 334ASP A 335ALA A 482 | 8PR A 701 |
4JLT_A_8PRA505 | 4jlt | 8PR DB00715(Paroxetine) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 8 | ILE A 101ILE A 114GLU A 218ALA A 298GLU A 301VAL A 367PRO A 368VAL A 477 | 8PR A 505 |
4L9I_A_8PRA601 | 4l9i | 8PR DB00715(Paroxetine) | Bos taurus | RHODOPSIN KINASE | PF00069(Pkinase)PF00615(RGS) | 7 | VAL A 201ALA A 214LEU A 218MET A 264MET A 267ASP A 271LEU A 321 | 8PR A 601 |
4L9I_B_8PRB601 | 4l9i | 8PR DB00715(Paroxetine) | Bos taurus | RHODOPSIN KINASE | no annotation | 8 | GLY B 196VAL B 201ALA B 214LYS B 216MET B 264MET B 267ASP B 271LEU B 321 | 8PR B 601 |
4MM4_A_8PRA603 | 4mm4 | 8PR DB00715(Paroxetine) | Aquifexaeolicus | TRANSPORTER | PF00209(SNF) | 14 | TYR A 21ASP A 24VAL A 104ALA A 105TYR A 107TYR A 108PHE A 253PHE A 259SER A 355SER A 356GLY A 359MET A 360ASP A 404THR A 408 | 8PR A 603 |
4MM4_B_8PRB603 | 4mm4 | 8PR DB00715(Paroxetine) | Aquifexaeolicus | TRANSPORTER | no annotation | 15 | TYR B 21ASP B 24VAL B 104ALA B 105TYR B 107TYR B 108VAL B 109PHE B 253PHE B 259SER B 355SER B 356GLY B 359MET B 360ASP B 404THR B 408 | 8PR B 603 |
5I6X_A_8PRA705 | 5i6x | 8PR DB00715(Paroxetine) | Homo sapiens | SODIUM-DEPENDENTSEROTONINTRANSPORTER | PF00209(SNF) | 10 | TYR A 95ASP A 98ALA A 169ILE A 172TYR A 176GLY A 338PHE A 341SER A 438GLY A 442VAL A 501 | 8PR A 705 |
6AWN_A_8PRA705 | 6awn | 8PR DB00715(Paroxetine) | Homo sapiens | SODIUM-DEPENDENTSEROTONINTRANSPORTER | no annotation | 11 | TYR A 95ASP A 98ALA A 169ILE A 172TYR A 176GLY A 338PHE A 341SER A 438THR A 439GLY A 442VAL A 501 | 8PR A 705 |
6F6I_A_8PRA509 | 6f6i | 8PR DB00715(Paroxetine) | Zaireebolavirus | ENVELOPEGLYCOPROTEIN;ENVELOPEGLYCOPROTEIN,GP,GP1 | no annotation | 12 | ARG A 64VAL A 66LEU A 68GLU A 100ALA A 101GLY A 102LEU A 186LEU B 515TYR B 517THR B 519MET B 548LEU B 558 | 8PR A 509 |