DRUG BINDING INTERFACES MAPPED TO '6V8'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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All hits from Homo Sapiens
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
5LF7_B_6V8B304
5lf7
6V8
DB09570(Ixazomib)
Homo sapiens
PROTEASOME SUBUNITBETA TYPE-6;PROTEASOME SUBUNITBETA TYPE-7
NonePF00227(Proteasome)PF10584(Proteasome_A_N)
12
THR b 2THR b 21THR b 22THR b 23ALA b 28LYS b 34ARG b 46SER b 47GLY b 48ALA b 50THR b 53TYR V 115
6V8 b 304
5LF7_H_6V8H305
5lf7
6V8
DB09570(Ixazomib)
Homo sapiens
PROTEASOME SUBUNITBETA TYPE-3;PROTEASOME SUBUNITBETA TYPE-7
PF00227(Proteasome)PF00227(Proteasome)PF12465(Pr_beta_C)
11
THR H 2ALA H 21THR H 22GLU H 23CYS H 32ALA H 47GLY H 48ALA H 50THR H 53ASP I 124LEU I 125
6V8 H 305
5LF7_K_6V8K305
5lf7
6V8
DB09570(Ixazomib)
Homo sapiens
PROTEASOME SUBUNITBETA TYPE-1;PROTEASOME SUBUNITBETA TYPE-5
PF00227(Proteasome)
11
THR K 2ALA K 21THR K 22ALA K 23VAL K 32LYS K 34MET K 46GLY K 48GLY K 49ALA K 50ASP L 125
6V8 K 305
5LF7_N_6V8N305
5lf7
6V8
DB09570(Ixazomib)
Homo sapiens
PROTEASOME SUBUNITBETA TYPE-6;PROTEASOME SUBUNITBETA TYPE-7
PF00227(Proteasome)PF00227(Proteasome)PF12465(Pr_beta_C)
12
THR N 2THR N 21THR N 22THR N 23ALA N 28LYS N 34ARG N 46SER N 47GLY N 48ALA N 50THR N 53TYR H 115
6V8 N 305
5LF7_V_6V8V303
5lf7
6V8
DB09570(Ixazomib)
Homo sapiens
PROTEASOME SUBUNITBETA TYPE-3;PROTEASOME SUBUNITBETA TYPE-7
None
11
THR V 2ALA V 21THR V 22GLU V 23CYS V 32ALA V 47GLY V 48ALA V 50THR V 53ASP W 124LEU W 125
6V8 V 303
5LF7_Y_6V8Y306
5lf7
6V8
DB09570(Ixazomib)
Homo sapiens
PROTEASOME SUBUNITBETA TYPE-1;PROTEASOME SUBUNITBETA TYPE-5
None
11
THR Y 2ALA Y 21THR Y 22ALA Y 23VAL Y 32LYS Y 34MET Y 46GLY Y 48GLY Y 49ALA Y 50ASP Z 125
6V8 Y 306
[["5LF7_B_6V8B304","5lf7","6V8","DB09570(Ixazomib)","Homo sapiens","PROTEASOME SUBUNIT BETA TYPE-6;PROTEASOME SUBUNIT BETA TYPE-7","None;PF00227(Proteasome);PF10584(Proteasome_A_N)",12,"THR b 2;THR b 21;THR b 22;THR b 23;ALA b 28;LYS b 34;ARG b 46;SER b 47;GLY b 48;ALA b 50;THR b 53;TYR V 115","6V8 b 304\r"],["5LF7_H_6V8H305","5lf7","6V8","DB09570(Ixazomib)","Homo sapiens","PROTEASOME SUBUNIT BETA TYPE-3;PROTEASOME SUBUNIT BETA TYPE-7","PF00227(Proteasome);PF00227(Proteasome);PF12465(Pr_beta_C)",11,"THR H 2;ALA H 21;THR H 22;GLU H 23;CYS H 32;ALA H 47;GLY H 48;ALA H 50;THR H 53;ASP I 124;LEU I 125","6V8 H 305\r"],["5LF7_K_6V8K305","5lf7","6V8","DB09570(Ixazomib)","Homo sapiens","PROTEASOME SUBUNIT BETA TYPE-1;PROTEASOME SUBUNIT BETA TYPE-5","PF00227(Proteasome)",11,"THR K 2;ALA K 21;THR K 22;ALA K 23;VAL K 32;LYS K 34;MET K 46;GLY K 48;GLY K 49;ALA K 50;ASP L 125","6V8 K 305\r"],["5LF7_N_6V8N305","5lf7","6V8","DB09570(Ixazomib)","Homo sapiens","PROTEASOME SUBUNIT BETA TYPE-6;PROTEASOME SUBUNIT BETA TYPE-7","PF00227(Proteasome);PF00227(Proteasome);PF12465(Pr_beta_C)",12,"THR N 2;THR N 21;THR N 22;THR N 23;ALA N 28;LYS N 34;ARG N 46;SER N 47;GLY N 48;ALA N 50;THR N 53;TYR H 115","6V8 N 305\r"],["5LF7_V_6V8V303","5lf7","6V8","DB09570(Ixazomib)","Homo sapiens","PROTEASOME SUBUNIT BETA TYPE-3;PROTEASOME SUBUNIT BETA TYPE-7","None",11,"THR V 2;ALA V 21;THR V 22;GLU V 23;CYS V 32;ALA V 47;GLY V 48;ALA V 50;THR V 53;ASP W 124;LEU W 125","6V8 V 303\r"],["5LF7_Y_6V8Y306","5lf7","6V8","DB09570(Ixazomib)","Homo sapiens","PROTEASOME SUBUNIT BETA TYPE-1;PROTEASOME SUBUNIT BETA TYPE-5","None",11,"THR Y 2;ALA Y 21;THR Y 22;ALA Y 23;VAL Y 32;LYS Y 34;MET Y 46;GLY Y 48;GLY Y 49;ALA Y 50;ASP Z 125","6V8 Y 306\r"]]