DRUG BINDING INTERFACES MAPPED TO 'Zika virus'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
5KQR_A_SAMA301 | 5kqr | SAM DB00118(S-Adenosylmethionine) | Zika virus | METHYLTRANSFERASE | PF01728(FtsJ) | 14 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110GLU A 111ASP A 131VAL A 132ASP A 146ILE A 147 | SAM A 301 |
5KQS_A_SAMA307 | 5kqs | SAM DB00118(S-Adenosylmethionine) | Zika virus | GENOME POLYPROTEIN | PF01728(FtsJ) | 13 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110ASP A 131VAL A 132ASP A 146ILE A 147 | SAM A 307 |
5M5B_A_SAMA1001 | 5m5b | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5METHYLTRANSFERASE | PF01728(FtsJ) | 14 | SER A 62GLY A 64GLY A 87GLY A 89GLY A 92TRP A 93THR A 110LYS A 111HIS A 116GLU A 117ASP A 137VAL A 138ASP A 152ILE A 153 | SAM A1001 |
5MFX_A_ACTA701 | 5mfx | ACT DB03166(Aceticacid) | Zika virus | GENOME POLYPROTEIN | PF00271(Flavi_DEAD)PF07652(Helicase_C) | 5 | ARG A 323THR A 449HIS A 450ALA A 478ASP A 481 | ACT A 701 |
5NJV_A_SAMA301 | 5njv | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5 | PF01728(FtsJ) | 14 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110GLU A 111ASP A 131VAL A 132ASP A 146ILE A 147 | SAM A 301 |
5NJV_B_SAMB301 | 5njv | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5 | None | 14 | SER B 56GLY B 58GLY B 81GLY B 83GLY B 86TRP B 87THR B 104LYS B 105HIS B 110GLU B 111ASP B 131VAL B 132ASP B 146ILE B 147 | SAM B 301 |
5NJV_C_SAMC301 | 5njv | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5 | None | 14 | SER C 56GLY C 58GLY C 81GLY C 83GLY C 86TRP C 87THR C 104LYS C 105HIS C 110GLU C 111ASP C 131VAL C 132ASP C 146ILE C 147 | SAM C 301 |
5NJV_D_SAMD301 | 5njv | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5 | None | 14 | SER D 56GLY D 58GLY D 81GLY D 83GLY D 86TRP D 87THR D 104LYS D 105HIS D 110GLU D 111ASP D 131VAL D 132ASP D 146ILE D 147 | SAM D 301 |
5VIM_A_SAMA301 | 5vim | SAM DB00118(S-Adenosylmethionine) | Zika virus | METHYLTRANSFERASE | PF01728(FtsJ) | 16 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110GLU A 111ASP A 131VAL A 132PHE A 133ASP A 146ILE A 147LYS A 182 | SAM A 301 |
5VIM_B_SAMB301 | 5vim | SAM DB00118(S-Adenosylmethionine) | Zika virus | METHYLTRANSFERASE | None | 16 | SER B 56GLY B 58GLY B 81GLY B 83GLY B 86TRP B 87THR B 104LYS B 105HIS B 110GLU B 111ASP B 131VAL B 132PHE B 133ASP B 146ILE B 147LYS B 182 | SAM B 301 |
5WZ1_A_SAMA601 | 5wz1 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5METHYLTRANSFERASE | PF01728(FtsJ) | 13 | SER A 58GLY A 60GLY A 83GLY A 88TRP A 89THR A 106LYS A 107HIS A 112GLU A 113ASP A 133VAL A 134ASP A 148ILE A 149 | SAM A 601 |
5WZ1_B_SAMB601 | 5wz1 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5METHYLTRANSFERASE | None | 14 | SER B 58GLY B 60GLY B 83GLY B 85GLY B 88TRP B 89THR B 106LYS B 107HIS B 112GLU B 113ASP B 133VAL B 134ASP B 148ILE B 149 | SAM B 601 |
5WZ1_C_SAMC601 | 5wz1 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5METHYLTRANSFERASE | None | 13 | SER C 58GLY C 60GLY C 83GLY C 88TRP C 89THR C 106LYS C 107HIS C 112GLU C 113ASP C 133VAL C 134ASP C 148ILE C 149 | SAM C 601 |
5WZ1_D_SAMD601 | 5wz1 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5METHYLTRANSFERASE | None | 13 | SER D 58GLY D 60GLY D 83GLY D 88TRP D 89THR D 106LYS D 107HIS D 112GLU D 113ASP D 133VAL D 134ASP D 148ILE D 149 | SAM D 601 |
5WZ1_E_SAME601 | 5wz1 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5METHYLTRANSFERASE | None | 13 | SER E 58GLY E 60GLY E 83GLY E 88TRP E 89THR E 106LYS E 107HIS E 112GLU E 113ASP E 133VAL E 134ASP E 148ILE E 149 | SAM E 601 |
5WZ1_F_SAMF601 | 5wz1 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5METHYLTRANSFERASE | None | 13 | SER F 58GLY F 60GLY F 83GLY F 88TRP F 89THR F 106LYS F 107HIS F 112GLU F 113ASP F 133VAL F 134ASP F 148ILE F 149 | SAM F 601 |
5WZ1_G_SAMG601 | 5wz1 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5METHYLTRANSFERASE | None | 13 | SER G 58GLY G 60GLY G 83GLY G 88TRP G 89THR G 106LYS G 107HIS G 112GLU G 113ASP G 133VAL G 134ASP G 148ILE G 149 | SAM G 601 |
5WZ1_H_SAMH601 | 5wz1 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5METHYLTRANSFERASE | None | 13 | SER H 58GLY H 60GLY H 83GLY H 88TRP H 89THR H 106LYS H 107HIS H 112GLU H 113ASP H 133VAL H 134ASP H 148ILE H 149 | SAM H 601 |
5WZ2_A_SAMA601 | 5wz2 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5 MTASE | PF01728(FtsJ) | 14 | SER A 58GLY A 60GLY A 83GLY A 85GLY A 88TRP A 89THR A 106LYS A 107HIS A 112GLU A 113ASP A 133VAL A 134ASP A 148ILE A 149 | SAM A 601 |
5WZ2_B_SAMB601 | 5wz2 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5 MTASE | None | 14 | SER B 58GLY B 60GLY B 83GLY B 85GLY B 88TRP B 89THR B 106LYS B 107HIS B 112GLU B 113ASP B 133VAL B 134ASP B 148ILE B 149 | SAM B 601 |
5WZ2_C_SAMC601 | 5wz2 | SAM DB00118(S-Adenosylmethionine) | Zika virus | NS5 MTASE | None | 14 | SER C 58GLY C 60GLY C 83GLY C 85GLY C 88TRP C 89THR C 106LYS C 107HIS C 112GLU C 113ASP C 133VAL C 134ASP C 148ILE C 149 | SAM C 601 |
5YOD_B_BEZB201 | 5yod | BEZ DB03793(BenzoicAcid) | Zika virus | NS3 PROTEASE | PF00949(Peptidase_S7) | 5 | HIS B 51ALA B 132SER B 135GLY B 151TYR B 161 | BEZ B 201 |
5YOD_D_BEZD201 | 5yod | BEZ DB03793(BenzoicAcid) | Zika virus | NS3 PROTEASE | None | 5 | HIS D 51ALA D 132SER D 135GLY D 151TYR D 161 | BEZ D 201 |
5YOD_F_BEZF201 | 5yod | BEZ DB03793(BenzoicAcid) | Zika virus | NS3 PROTEASE | None | 5 | HIS F 51ALA F 132SER F 135TYR F 150TYR F 161 | BEZ F 201 |
5YOD_H_BEZH201 | 5yod | BEZ DB03793(BenzoicAcid) | Zika virus | NS3 PROTEASE | None | 5 | HIS H 51SER H 135TYR H 150GLY H 151TYR H 161 | BEZ H 201 |
5ZMQ_I_PACI1 | 5zmq | PAC DB09269(Phenylaceticacid) | Zika virus;syntheticconstruct | SERINE PROTEASE NS3;SERINE PROTEASESUBUNIT NS2B;PEPTIDEPAC-DLY-DLY-DAR | None | 3 | GLU E 66VAL D 155TYR D 161 | PAC I 1 |
5ZMQ_K_PACK1 | 5zmq | PAC DB09269(Phenylaceticacid) | Zika virus;syntheticconstruct | SERINE PROTEASE NS3;PEPTIDEPAC-DLY-DLY-DAR | None | 3 | ALA H 132VAL H 155TYR H 161 | PAC K 1 |