DRUG BINDING INTERFACES MAPPED TO 'Streptomyces clavuligerus'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1UOB_A_PNNA1311 | 1uob | PNN DB01053(Benzylpenicillin) | Streptomycesclavuligerus | DEACETOXYCEPHALOSPORIN C SYNTHETASE | PF03171(DIOX_N)PF14226(2OG-FeII_Oxy) | 15 | MET A 73SER A 102LEU A 158ARG A 160ARG A 162MET A 180HIS A 183ASP A 185ILE A 192LEU A 204HIS A 243SER A 260VAL A 262PHE A 264ILE A 305 | PNN A1311 |
1UOF_A_PNNA1312 | 1uof | PNN DB01053(Benzylpenicillin) | Streptomycesclavuligerus | DEACETOXYCEPHALOSPORIN C SYNTHETASE | PF03171(2OG-FeII_Oxy)PF14226(DIOX_N) | 11 | PHE A 164ARG A 179MET A 180HIS A 183ASP A 185THR A 190HIS A 243VAL A 245ARG A 258SER A 260VAL A 262 | PNN A1312 |
2BM9_A_SAMA301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | PF04989(CmcI) | 15 | LEU A 18LEU A 64LYS A 65GLU A 87GLY A 89TYR A 91SER A 95ASP A 116ARG A 117ARG A 121ASP A 138CYS A 139ASN A 160ALA A 161ALA A 163 | SAM A 301 |
2BM9_B_SAMB301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 13 | LEU B 18LEU B 64LYS B 65GLU B 87GLY B 89SER B 95ASP B 116ARG B 117ARG B 121ASP B 138CYS B 139ASN B 160ALA B 163 | SAM B 301 |
2BM9_C_SAMC301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 16 | LEU C 18LEU C 64LYS C 65GLU C 87GLY C 89TYR C 91ASN C 92SER C 95ASP C 116ARG C 117ARG C 121ASP C 138CYS C 139ASN C 160ALA C 161ALA C 163 | SAM C 301 |
2BM9_D_SAMD301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 15 | LEU D 18LEU D 64LYS D 65GLU D 87GLY D 89TYR D 91SER D 95ASP D 116ARG D 117ARG D 121ASP D 138CYS D 139ASN D 160ALA D 161ALA D 163 | SAM D 301 |
2BM9_E_SAME301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 14 | LEU E 18LEU E 64LYS E 65GLU E 87GLY E 89SER E 95ASP E 116ARG E 117ARG E 121ASP E 138CYS E 139ASN E 160ALA E 161ALA E 163 | SAM E 301 |
2BM9_F_SAMF301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 13 | GLY F 17LEU F 18LEU F 64GLY F 89ASP F 116ARG F 117ARG F 121CYS F 139ASN F 160ALA F 161HIS F 162ALA F 163ASP F 187 | SAM F 301 |
2BR4_A_SAMA301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | PF04989(CmcI) | 15 | LEU A 18LEU A 64LYS A 65GLU A 87GLY A 89TYR A 91SER A 95ASP A 116ARG A 117ARG A 121ASP A 138CYS A 139ASP A 160ALA A 161ALA A 163 | SAM A 301 |
2BR4_B_SAMB301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 16 | LEU B 18LEU B 64LYS B 65GLU B 87GLY B 89TYR B 91ASN B 92SER B 95ASP B 116ARG B 117ARG B 121ASP B 138CYS B 139ASP B 160ALA B 161ALA B 163 | SAM B 301 |
2BR4_C_SAMC301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 16 | LEU C 18LEU C 64LYS C 65GLU C 87GLY C 89TYR C 91SER C 95ASP C 116ARG C 117ARG C 121ASP C 138CYS C 139SER C 140ASP C 160ALA C 161ALA C 163 | SAM C 301 |
2BR4_D_SAMD301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 15 | LEU D 18LEU D 64LYS D 65GLU D 87GLY D 89TYR D 91SER D 95ASP D 116ARG D 117ARG D 121ASP D 138CYS D 139ASP D 160ALA D 161ALA D 163 | SAM D 301 |
2BR4_E_SAME301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 15 | LEU E 18LEU E 64LYS E 65GLU E 87GLY E 89TYR E 91SER E 95ASP E 116ARG E 117ARG E 121ASP E 138CYS E 139ASP E 160ALA E 161ALA E 163 | SAM E 301 |
2BR4_F_SAMF301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 15 | LEU F 18LEU F 64LYS F 65GLU F 87GLY F 89TYR F 91SER F 95ASP F 116ARG F 117ARG F 121ASP F 138CYS F 139ASP F 160ALA F 161ALA F 163 | SAM F 301 |
2JAP_A_J01A1249 | 2jap | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | CLAVALDEHYDEDEHYDROGENASE | PF00106(adh_short) | 13 | MET A 95LEU A 97SER A 142ILE A 143ALA A 144VAL A 149ALA A 152TYR A 155GLN A 156THR A 187LEU A 192TYR A 205ARG A 208 | J01 A1249 |
2JAP_B_J01B1249 | 2jap | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | CLAVALDEHYDEDEHYDROGENASE | no annotation | 13 | MET B 95LEU B 97SER B 142ILE B 143ALA B 144VAL B 149ALA B 152TYR B 155GLN B 156THR B 187LEU B 192TYR B 205ARG B 208 | J01 B1249 |
2JAP_C_J01C1249 | 2jap | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | CLAVALDEHYDEDEHYDROGENASE | no annotation | 13 | MET C 95LEU C 97SER C 142ILE C 143ALA C 144VAL C 149ALA C 152TYR C 155GLN C 156THR C 187LEU C 192TYR C 205ARG C 208 | J01 C1249 |
2JAP_D_J01D1249 | 2jap | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | CLAVALDEHYDEDEHYDROGENASE | no annotation | 13 | MET D 95LEU D 97SER D 142ILE D 143ALA D 144VAL D 149ALA D 152TYR D 155GLN D 156THR D 187LEU D 192TYR D 205ARG D 208 | J01 D1249 |
2XF3_A_J01A500 | 2xf3 | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | PF13354(Beta-lactamase2) | 10 | HIS A 84TRP A 91VAL A 93ILE A 103LEU A 362LEU A 415ARG A 418GLY A 419ALA A 422LYS A 423 | J01 A 500 |
2XF3_A_J01A600 | 2xf3 | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | PF13354(Beta-lactamase2) | 11 | LYS A 89SER A 173THR A 209SER A 234TYR A 359ALA A 376GLY A 377SER A 378MET A 383PHE A 385ARG A 418 | J01 A 600 |
2XF3_B_J01B500 | 2xf3 | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | no annotation | 9 | HIS B 84TRP B 91VAL B 93ILE B 103LEU B 362ARG B 418GLY B 419ALA B 422LYS B 423 | J01 B 500 |
2XF3_B_J01B600 | 2xf3 | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | no annotation | 11 | LYS B 89SER B 173THR B 209SER B 234TYR B 359ALA B 376GLY B 377SER B 378MET B 383PHE B 385ARG B 418 | J01 B 600 |
2XFS_A_J01A500 | 2xfs | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | PF13354(Beta-lactamase2) | 8 | HIS A 84TRP A 91VAL A 93LEU A 362ARG A 418GLY A 419ALA A 422LYS A 423 | J01 A 500 |
2XFS_A_J01A600 | 2xfs | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | PF13354(Beta-lactamase2) | 10 | LYS A 89THR A 209SER A 234TYR A 359ALA A 376GLY A 377SER A 378MET A 383PHE A 385ARG A 418 | J01 A 600 |
2XFS_B_J01B500 | 2xfs | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | no annotation | 9 | HIS B 84TRP B 91VAL B 93ILE B 103LEU B 362ARG B 418GLY B 419ALA B 422LYS B 423 | J01 B 500 |
2XFS_B_J01B600 | 2xfs | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | no annotation | 11 | LYS B 89ALA B 173THR B 209SER B 234TYR B 359ALA B 376GLY B 377SER B 378MET B 383PHE B 385ARG B 418 | J01 B 600 |
2XH9_A_J01A1436 | 2xh9 | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | PF13354(Beta-lactamase2) | 8 | HIS A 84TRP A 91VAL A 93LEU A 362ARG A 418GLY A 419ALA A 422LYS A 423 | J01 A1436 |
2XH9_A_J01A1437 | 2xh9 | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | PF13354(Beta-lactamase2) | 11 | LYS A 89SER A 173THR A 209SER A 234TYR A 359ALA A 376GLY A 377ALA A 378MET A 383PHE A 385ARG A 418 | J01 A1437 |
2XH9_B_J01B1436 | 2xh9 | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | no annotation | 9 | HIS B 84TRP B 91VAL B 93ILE B 103LEU B 362ARG B 418GLY B 419ALA B 422LYS B 423 | J01 B1436 |
2XH9_B_J01B1437 | 2xh9 | J01 DB00766(Clavulanate) | Streptomycesclavuligerus | ORF12 | no annotation | 10 | LYS B 89SER B 173THR B 209SER B 234TYR B 359ALA B 376GLY B 377ALA B 378PHE B 385ARG B 418 | J01 B1437 |