DRUG BINDING INTERFACES MAPPED TO 'Schistosoma mansoni'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
3E9R_A_ACTA700 | 3e9r | ACT DB03166(Aceticacid) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 6 | GLY A 120TYR A 202GLU A 203GLY A 220MET A 221ASN A 245 | ACT A 700 |
3E9R_C_ACTC700 | 3e9r | ACT DB03166(Aceticacid) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | None | 6 | GLY C 120TYR C 202GLU C 203GLY C 220MET C 221ASN C 245 | ACT C 700 |
3F8W_A_ADNA300 | 3f8w | ADN DB00640(Adenosine) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 14 | SER A 35TYR A 90ALA A 118GLY A 120PHE B 161TYR A 202GLU A 203VAL A 219GLY A 220MET A 221THR A 244ASN A 245HIS A 259VAL A 262 | ADN A 300 |
3F8W_B_ADNB301 | 3f8w | ADN DB00640(Adenosine) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | no annotation | 13 | SER B 35HIS B 88TYR B 90GLY B 120TYR B 202GLU B 203VAL B 219GLY B 220MET B 221THR B 244ASN B 245HIS B 259VAL B 262 | ADN B 301 |
3F8W_C_ADNC302 | 3f8w | ADN DB00640(Adenosine) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 15 | SER C 35HIS C 88TYR C 90ALA C 118GLY C 120PHE A 161TYR C 202GLU C 203VAL C 219GLY C 220MET C 221THR C 244ASN C 245HIS C 259VAL C 262 | ADN C 302 |
3UQ6_A_ADNA401 | 3uq6 | ADN DB00640(Adenosine) | Schistosomamansoni | ADENOSINE KINASE,PUTATIVE | PF00294(PfkB) | 17 | ASN A 14LEU A 16ASP A 18ILE A 38LEU A 40GLY A 63GLY A 64ALA A 65ASN A 68VAL A 123MET A 134THR A 136LEU A 138PHE A 169ASN A 298GLY A 299ASP A 302 | ADN A 401 |
3UQ6_B_ADNB401 | 3uq6 | ADN DB00640(Adenosine) | Schistosomamansoni | ADENOSINE KINASE,PUTATIVE | no annotation | 17 | ASN B 14LEU B 16ASP B 18ILE B 38LEU B 40GLY B 63GLY B 64ALA B 65ASN B 68VAL B 123MET B 134THR B 136LEU B 138PHE B 169ASN B 298GLY B 299ASP B 302 | ADN B 401 |
3VAQ_A_ADNA401 | 3vaq | ADN DB00640(Adenosine) | Schistosomamansoni | PUTATIVE ADENOSINEKINASE | PF00294(PfkB) | 16 | ASN A 14LEU A 16ASP A 18ILE A 38LEU A 40GLY A 63GLY A 64ALA A 65ASN A 68VAL A 123THR A 136LEU A 138PHE A 169ASN A 298GLY A 299ASP A 302 | ADN A 401 |
3VAQ_B_ADNB401 | 3vaq | ADN DB00640(Adenosine) | Schistosomamansoni | PUTATIVE ADENOSINEKINASE | no annotation | 16 | ASN B 14LEU B 16ASP B 18ILE B 38LEU B 40GLY B 63GLY B 64ALA B 65ASN B 68VAL B 123MET B 134THR B 136LEU B 138PHE B 169GLY B 299ASP B 302 | ADN B 401 |
3VAS_A_ADNA401 | 3vas | ADN DB00640(Adenosine) | Schistosomamansoni | PUTATIVE ADENOSINEKINASE | PF00294(PfkB) | 16 | ASN A 14LEU A 16ASP A 18ILE A 38LEU A 40GLY A 63GLY A 64ALA A 65ASN A 68VAL A 123THR A 136LEU A 138PHE A 169ASN A 298GLY A 299ASP A 302 | ADN A 401 |
3VAS_B_ADNB401 | 3vas | ADN DB00640(Adenosine) | Schistosomamansoni | PUTATIVE ADENOSINEKINASE | no annotation | 17 | ASN B 14LEU B 16ASP B 18ILE B 38LEU B 40GLY B 63GLY B 64ALA B 65ASN B 68VAL B 123MET B 134THR B 136LEU B 138PHE B 169ASN B 298GLY B 299ASP B 302 | ADN B 401 |
4BZ6_A_SHHA700 | 4bz6 | SHH DB02546(Vorinostat) | Schistosomamansoni | HISTONE DEACETYLASE8 | PF00850(Hist_deacetyl) | 10 | LYS A 20HIS A 141HIS A 142ASP A 186HIS A 188ASP A 285PRO A 291HIS A 292GLY A 339TYR A 341 | SHH A 700 |
4BZ6_B_SHHB700 | 4bz6 | SHH DB02546(Vorinostat) | Schistosomamansoni | HISTONE DEACETYLASE8 | PF00850(Hist_deacetyl)no annotation | 12 | LYS B 20ASP A 50HIS B 141HIS B 142ASP B 186HIS B 188PHE B 216ASP B 285PRO B 291HIS B 292GLY B 339TYR B 341 | SHH B 700 |
4BZ6_C_SHHC700 | 4bz6 | SHH DB02546(Vorinostat) | Schistosomamansoni | HISTONE DEACETYLASE8 | no annotation | 13 | LYS C 20ASP D 50HIS C 141HIS C 142GLY C 150ASP C 186HIS C 188PHE C 216ASP C 285PRO C 291HIS C 292GLY C 339TYR C 341 | SHH C 700 |
4BZ6_D_SHHD700 | 4bz6 | SHH DB02546(Vorinostat) | Schistosomamansoni | HISTONE DEACETYLASE8 | no annotation | 10 | LYS D 20HIS D 141HIS D 142ASP D 186HIS D 188ASP D 285PRO D 291HIS D 292GLY D 339TYR D 341 | SHH D 700 |
4DC3_A_ADNA401 | 4dc3 | ADN DB00640(Adenosine) | Schistosomamansoni | ADENOSINE KINASE | PF00294(PfkB) | 16 | ASN A 14LEU A 16ASP A 18ILE A 38LEU A 40GLY A 63GLY A 64ALA A 65ASN A 68VAL A 123MET A 134THR A 136LEU A 138PHE A 169GLY A 299ASP A 302 | ADN A 401 |
4DC3_B_2FAB401 | 4dc3 | 2FA DB01073(Fludarabine) | Schistosomamansoni | ADENOSINE KINASE | no annotation | 17 | ASN B 14LEU B 16ASP B 18ILE B 38LEU B 40GLY B 63GLY B 64ALA B 65ASN B 68VAL B 123MET B 134THR B 136LEU B 138PHE B 169ASN B 298GLY B 299ASP B 302 | 2FA B 401 |
4MUB_A_OAQA302 | 4mub | OAQ DB01096(Oxamniquine) | Schistosomamansoni | SULFOTRANSFERASE | PF17784(Sulfotransfer_4) | 13 | PRO A 16HIS A 37MET A 38PHE A 39ASP A 91LEU A 92VAL A 128GLY A 143ASP A 144PHE A 153THR A 157MET A 233THR A 237 | OAQ A 302 |
4TXN_A_URFA302 | 4txn | URF DB00544(Fluorouracil) | Schistosomamansoni | URIDINEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 7 | THR A 124GLY A 126GLN A 201ARG A 203MET A 233ALA A 256ILE A 265 | URF A 302 |
4TXN_B_URFB302 | 4txn | URF DB00544(Fluorouracil) | Schistosomamansoni | URIDINEPHOSPHORYLASE | no annotation | 7 | THR B 124GLY B 126GLN B 201ARG B 203MET B 233ALA B 256ILE B 265 | URF B 302 |
4TXN_C_URFC302 | 4txn | URF DB00544(Fluorouracil) | Schistosomamansoni | URIDINEPHOSPHORYLASE | no annotation | 7 | THR C 124GLY C 126GLN C 201ARG C 203MET C 233ALA C 256ILE C 265 | URF C 302 |
4TXN_D_URFD302 | 4txn | URF DB00544(Fluorouracil) | Schistosomamansoni | URIDINEPHOSPHORYLASE | no annotation | 7 | THR D 124GLY D 126GLN D 201ARG D 203MET D 233ALA D 256ILE D 265 | URF D 302 |
5BYJ_A_OQRA302 | 5byj | OQR DB01096(Oxamniquine) | Schistosomamansoni | SULFOTRANSFERASE | PF17784(Sulfotransfer_4) | 14 | HIS A 37MET A 38PHE A 39ILE A 42ASP A 91LEU A 92VAL A 128GLY A 143ASP A 144PHE A 153THR A 157MET A 233LEU A 236THR A 237 | OQR A 302 |
5BYK_A_OAQA302 | 5byk | OAQ DB01096(Oxamniquine) | Schistosomamansoni | SULFOTRANSFERASE | PF17784(Sulfotransfer_4) | 14 | PRO A 16HIS A 37MET A 38ILE A 42ASP A 91LEU A 92VAL A 127VAL A 128ASP A 144LEU A 147PHE A 153THR A 157MET A 233THR A 237 | OAQ A 302 |
6B4Y_A_OAQA302 | 6b4y | OAQ DB01096(Oxamniquine) | Schistosomamansoni | SULFOTRANSFERASEOXAMNIQUINERESISTANCE PROTEIN | PF17784(Sulfotransfer_4) | 10 | MET A 38ILE A 42ASP A 91LEU A 92VAL A 128ASP A 144PHE A 153THR A 157MET A 233THR A 237 | OAQ A 302 |
6B50_A_OAQA302 | 6b50 | OAQ DB01096(Oxamniquine) | Schistosomamansoni | SULFOTRANSFERASEOXAMNIQUINERESISTANCE PROTEIN | PF17784(Sulfotransfer_4) | 12 | PRO A 16HIS A 37MET A 38ASP A 91LEU A 92VAL A 127VAL A 128ASP A 144PHE A 153SER A 157MET A 233THR A 237 | OAQ A 302 |