DRUG BINDING INTERFACES MAPPED TO 'Ovis aries'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1CQE_A_FLPA1650 | 1cqe | FLP DB00712(Flurbiprofen) | Ovis aries | PROTEIN(PROSTAGLANDIN H2SYNTHASE-1) | PF00008(EGF)PF03098(An_peroxidase) | 13 | VAL A 116ARG A 120VAL A 349LEU A 352TYR A 355LEU A 359TYR A 385TRP A 387ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | FLP A1650 |
1CQE_B_FLPB2650 | 1cqe | FLP DB00712(Flurbiprofen) | Ovis aries | PROTEIN(PROSTAGLANDIN H2SYNTHASE-1) | no annotation | 13 | VAL B 116ARG B 120VAL B 349LEU B 352TYR B 355LEU B 359TYR B 385TRP B 387ILE B 523GLY B 526ALA B 527SER B 530LEU B 531 | FLP B2650 |
1EQG_A_IBPA701 | 1eqg | IBP DB01050(Ibuprofen) | Ovis aries | PROSTAGLANDIN H2SYNTHASE-1 | PF00008(EGF)PF03098(An_peroxidase) | 9 | VAL A 116ARG A 120VAL A 349TYR A 355LEU A 359ILE A 523ALA A 527SER A 530LEU A 531 | IBP A 701 |
1EQG_B_IBPB1701 | 1eqg | IBP DB01050(Ibuprofen) | Ovis aries | PROSTAGLANDIN H2SYNTHASE-1 | no annotation | 11 | VAL B 116ARG B 120VAL B 349SER B 353TYR B 355LEU B 359TYR B 385ILE B 523ALA B 527SER B 530LEU B 531 | IBP B1701 |
1EQH_A_FLPA701 | 1eqh | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN H2SYNTHASE-1 | PF00008(EGF)PF03098(An_peroxidase) | 13 | VAL A 116ARG A 120VAL A 349LEU A 352TYR A 355LEU A 359TYR A 385TRP A 387ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | FLP A 701 |
1EQH_B_FLPB1701 | 1eqh | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN H2SYNTHASE-1 | no annotation | 13 | VAL B 116ARG B 120VAL B 349LEU B 352TYR B 355LEU B 359TYR B 385TRP B 387ILE B 523GLY B 526ALA B 527SER B 530LEU B 531 | FLP B1701 |
1FE2_A_LAXA700 | 1fe2 | LAX DB00154(Dihomo-gamma-linolenicacid) | Ovis aries | PROSTAGLANDINENDOPEROXIDE HSYNTHASE-1 | PF00008(EGF)PF03098(An_peroxidase) | 22 | VAL A 116ARG A 120PHE A 205PHE A 209VAL A 228VAL A 344TYR A 348VAL A 349LEU A 352TYR A 355ASN A 375PHE A 381TYR A 385TRP A 387PHE A 518ILE A 523GLY A 526ALA A 527SER A 530LEU A 531GLY A 533LEU A 534 | LAX A 700 |
1IGX_A_EPAA700 | 1igx | EPA DB00159(Icosapent) | Ovis aries | PROSTAGLANDINENDOPEROXIDE HSYNTHASE-1 | PF00008(EGF)PF03098(An_peroxidase) | 20 | VAL A 116ARG A 120PHE A 205PHE A 209VAL A 344TYR A 348VAL A 349LEU A 352SER A 353TYR A 355PHE A 381TYR A 385TRP A 387ILE A 523GLY A 526ALA A 527SER A 530LEU A 531GLY A 533LEU A 534 | EPA A 700 |
1PTH_A_SALA710 | 1pth | SAL DB00936(Salicylicacid) | Ovis aries | PROSTAGLANDIN H2SYNTHASE-1 | PF00008(EGF)PF03098(An_peroxidase) | 7 | VAL A 116ARG A 120VAL A 349LEU A 352TYR A 355ALA A 527LEU A 531 | SAL A 710 |
1PTH_B_SALB711 | 1pth | SAL DB00936(Salicylicacid) | Ovis aries | PROSTAGLANDIN H2SYNTHASE-1 | no annotation | 7 | VAL B 116ARG B 120VAL B 349LEU B 352TYR B 355ALA B 527LEU B 531 | SAL B 711 |
2AYL_A_FLPA1701 | 2ayl | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 14 | VAL A 116ARG A 120VAL A 349LEU A 352TYR A 355LEU A 359TYR A 385TRP A 387PHE A 518ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | FLP A1701 |
2AYL_B_FLPB2701 | 2ayl | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 13 | VAL B1116ARG B1120VAL B1349LEU B1352TYR B1355LEU B1359TYR B1385TRP B1387ILE B1523GLY B1526ALA B1527SER B1530LEU B1531 | FLP B2701 |
3KK6_A_CELA701 | 3kk6 | CEL DB00482(Celecoxib) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 18 | HIS A 90VAL A 116GLN A 192VAL A 349LEU A 352SER A 353TYR A 355LEU A 359LEU A 384TRP A 387SER A 516ILE A 517PHE A 518ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | CEL A 701 |
3KK6_B_CELB1701 | 3kk6 | CEL DB00482(Celecoxib) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 18 | HIS B 90VAL B 116GLN B 192VAL B 349LEU B 352SER B 353TYR B 355LEU B 359LEU B 384TRP B 387SER B 516ILE B 517PHE B 518ILE B 523GLY B 526ALA B 527SER B 530LEU B 531 | CEL B1701 |
3N8W_A_FLPA701 | 3n8w | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 12 | VAL A 116ARG A 120VAL A 349LEU A 352TYR A 355LEU A 359TYR A 385TRP A 387GLY A 526ALA A 527SER A 530LEU A 531 | FLP A 701 |
3N8X_A_NIMA701 | 3n8x | NIM DB04743(Nimesulide) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 15 | HIS A 90ARG A 120VAL A 349LEU A 352SER A 353TYR A 355LEU A 359TYR A 385TRP A 387PHE A 518ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | NIM A 701 |
3N8X_B_NIMB1701 | 3n8x | NIM DB04743(Nimesulide) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 15 | HIS B 90VAL B 116ARG B 120VAL B 349LEU B 352SER B 353TYR B 355LEU B 359TRP B 387PHE B 518ILE B 523GLY B 526ALA B 527SER B 530LEU B 531 | NIM B1701 |
3N8Y_A_DIFA701 | 3n8y | DIF DB00586(Diclofenac) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 11 | VAL A 349LEU A 352SER A 353TYR A 355TYR A 385TRP A 387ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | DIF A 701 |
3N8Y_B_DIFB585 | 3n8y | DIF DB00586(Diclofenac) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 12 | VAL B 344VAL B 349LEU B 352SER B 353TYR B 355TYR B 385TRP B 387ILE B 523GLY B 526ALA B 527LEU B 531LEU B 534 | DIF B 585 |
3N8Y_B_SALB900 | 3n8y | SAL DB00936(Salicylicacid) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 5 | VAL B 349LEU B 352TYR B 355ILE B 523ALA B 527 | SAL B 900 |
3N8Z_A_FLPA701 | 3n8z | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 12 | VAL A 116ARG A 120VAL A 349LEU A 352TYR A 355LEU A 359TYR A 385TRP A 387GLY A 526ALA A 527SER A 530LEU A 531 | FLP A 701 |
3N8Z_B_FLPB1701 | 3n8z | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 13 | VAL B 116ARG B 120VAL B 349LEU B 352TYR B 355LEU B 384TYR B 385TRP B 387ILE B 523GLY B 526ALA B 527SER B 530LEU B 531 | FLP B1701 |
3UT5_B_LOCB502 | 3ut5 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | ALA A 180VAL A 181CYS B 241LEU B 242ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 502 |
3UT5_D_LOCD502 | 3ut5 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 14 | ALA C 180VAL C 181CYS D 241LEU D 242GLN D 247ALA D 250LYS D 254LEU D 255ASN D 258MET D 259ALA D 316LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4EB6_C_VLBC503 | 4eb6 | VLB DB00570(Vinblastine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C)no annotation | 12 | VAL B 177ASP B 179TYR B 210THR B 221PRO B 222TYR B 224PRO C 325ASN C 329ILE C 332LYS C 336VAL C 353ILE C 355 | VLB C 503 |
4LUF_A_ACTA605 | 4luf | ACT DB03166(Aceticacid) | Ovis aries | SERUM ALBUMIN | PF00273(Serum_albumin) | 4 | ALA A 26HIS A 67PHE A 70LEU A 250 | ACT A 605 |
4LUH_A_ACTA608 | 4luh | ACT DB03166(Aceticacid) | Ovis aries | SERUM ALBUMIN | PF00273(Serum_albumin) | 4 | PRO A 110ASP A 111LEU A 112ARG A 144 | ACT A 608 |
4LUH_A_ACTA609 | 4luh | ACT DB03166(Aceticacid) | Ovis aries | SERUM ALBUMIN | PF00273(Serum_albumin) | 4 | ALA A 26HIS A 67PHE A 70LEU A 250 | ACT A 609 |
4LUH_A_ACTA610 | 4luh | ACT DB03166(Aceticacid) | Ovis aries | SERUM ALBUMIN | PF00273(Serum_albumin) | 3 | VAL A 417SER A 418THR A 421 | ACT A 610 |
4O1Z_A_MXMA807 | 4o1z | MXM DB00814(Meloxicam) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 18 | MET A 113VAL A 116LEU A 117ARG A 120ILE A 345VAL A 349LEU A 352LEU A 359TRP A 387PHE A 518MET A 522ILE A 523GLY A 526ALA A 527SER A 530LEU A 531LEU A 534LEU A 535 | MXM A 807 |
4O1Z_B_MXMB807 | 4o1z | MXM DB00814(Meloxicam) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 13 | MET B 113VAL B 116LEU B 117ARG B 120ILE B 345VAL B 349LEU B 359TRP B 387PHE B 518MET B 522ALA B 527SER B 530LEU B 531 | MXM B 807 |
4X1I_B_LOCB502 | 4x1i | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | SER A 178ALA A 180VAL A 181CYS B 241LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316VAL B 318LYS B 352ALA B 354 | LOC B 502 |
4X1I_D_LOCD502 | 4x1i | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 14 | ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4X1K_B_LOCB502 | 4x1k | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 12 | SER A 178VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258THR B 314LYS B 352ALA B 354 | LOC B 502 |
4X1K_D_LOCD502 | 4x1k | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 17 | ASN C 101SER C 178ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316VAL D 318LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4X1Y_B_LOCB502 | 4x1y | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316VAL B 318LYS B 352ILE B 378 | LOC B 502 |
4X1Y_D_LOCD502 | 4x1y | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 16 | SER C 178ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316VAL D 318LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4X20_B_LOCB502 | 4x20 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 16 | SER A 178VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316VAL B 318LYS B 352ALA B 354ILE B 378 | LOC B 502 |
4X20_D_LOCD502 | 4x20 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 14 | SER C 178ALA C 180VAL C 181LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316VAL D 318LYS D 352ILE D 378 | LOC D 502 |
5EYP_B_LOCB502 | 5eyp | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 17 | SER A 178ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ALA B 354ILE B 378 | LOC B 502 |
5MIO_B_LOCB502 | 5mio | LOC DB01394(Colchicine) | Bos taurus;Ovis aries | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 502 |