DRUG BINDING INTERFACES MAPPED TO 'Methanocaldococcus jannaschii'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
Filter list by:
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1MT1_A_AG2A7005 1mt1 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		PF01862
(PvlArgDC)
no annotation 		6 LEU A  31
ASP A  35
LEU A  38
ILE F  54
GLU F 109
ARG F 134
 AG2 A7005
1MT1_B_AG2B7001 1mt1 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		PF01862
(PvlArgDC)
no annotation 		6 LEU C  31
ASP C  35
LEU C  38
ILE B  54
GLU B 109
ARG B 134
 AG2 B7001
1MT1_C_AG2C7004 1mt1 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		no annotation 6 LEU E  31
ASP E  35
LEU E  38
ALA D  76
LEU D 106
GLU D 109
 AG2 C7004
1MT1_G_AG2G7003 1mt1 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		no annotation 6 LEU G  31
ASP G  35
LEU G  38
GLY G  44
ILE J  54
ARG J 134
 AG2 G7003
1MT1_K_AG2K7002 1mt1 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		no annotation 7 LEU K  31
ASP K  35
LEU K  38
GLY K  44
ILE H  54
GLU H 109
ARG H 134
 AG2 K7002
1N13_B_AG2B7011 1n13 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		PF01862
(PvlArgDC)
no annotation 		5 LEU C  31
ASP C  35
LEU C  38
GLU B 109
ARG B 134
 AG2 B7011
1N13_D_AG2D7015 1n13 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		no annotation 7 LEU E  31
ASP E  35
LEU E  38
GLY E  44
LEU D 106
GLU D 109
ARG D 134
 AG2 D7015
1N13_F_AG2F7016 1n13 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		PF01862
(PvlArgDC)
no annotation 		8 LEU A  31
ASP A  35
LEU A  38
GLY A  44
ILE F  54
MET F 108
GLU F 109
ARG F 134
 AG2 F7016
1N13_H_AG2H7012 1n13 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		no annotation 6 LEU K  31
ASP K  35
LEU K  38
GLY K  44
GLU H 109
ARG H 134
 AG2 H7012
1N13_J_AG2J7013 1n13 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		no annotation 7 LEU G  31
ASP G  35
LEU G  38
GLY G  44
MET J 108
GLU J 109
ARG J 134
 AG2 J7013
1N13_L_AG2L7014 1n13 AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN;
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN 		no annotation 7 LEU I  31
ASP I  35
LEU I  38
ILE L  54
MET L 108
GLU L 109
ARG L 134
 AG2 L7014
1TUF_A_AZ1A502 1tuf AZ1

DB00548
(Azelaic
Acid) 		Methanocaldococcu
s jannaschii 		DIAMINOPIMELATE
DECARBOXYLASE 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N)
no annotation 		9 HIS A 224
GLY A 226
SER A 227
ARG A 307
ARG A 343
TYR A 347
GLU B 373
SER B 374
TYR B 409
 AZ1 A 502
1TUF_B_AZ1B503 1tuf AZ1

DB00548
(Azelaic
Acid) 		Methanocaldococcu
s jannaschii 		DIAMINOPIMELATE
DECARBOXYLASE 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N)
no annotation 		6 SER B 227
ARG B 307
ARG B 343
TYR B 347
GLU A 373
TYR B 401
 AZ1 B 503
2C49_A_ADNA1301 2c49 ADN

DB00640
(Adenosine) 		Methanocaldococcu
s jannaschii 		SUGAR KINASE MJ0406 PF00294
(PfkB)
no annotation 		16 HIS A  13
ALA A  15
ASP A  17
SER B  31
GLN B  33
GLY A  42
GLY A  43
ASN A  47
ALA A  99
ILE A 101
THR A 111
PHE A 113
GLN A 163
ASP A 164
ASP A 247
CYS A 283
 ADN A1301
2C49_B_ADNB1301 2c49 ADN

DB00640
(Adenosine) 		Methanocaldococcu
s jannaschii 		SUGAR KINASE MJ0406 no annotation 7 HIS B  13
ALA B  15
ASP B  17
GLY B  42
GLY B  43
ASN B  47
PHE B 113
 ADN B1301
2J9C_A_ACTA1121 2j9c ACT

DB03166
(Acetic
acid) 		Methanocaldococcu
s jannaschii 		HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059 		None
PF00543
(P-II) 		5 SER A  31
SER C  31
SER B  31
VAL B  33
VAL A  33
 ACT A1121
2J9C_A_ACTA1122 2j9c ACT

DB03166
(Acetic
acid) 		Methanocaldococcu
s jannaschii 		HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059 		None
PF00543
(P-II) 		7 SER A  31
SER C  31
SER B  31
VAL B  33
LYS B  60
LYS A  60
LYS C  60
 ACT A1122
2J9C_C_ACTC1120 2j9c ACT

DB03166
(Acetic
acid) 		Methanocaldococcu
s jannaschii 		HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059 		None 3 LYS C  34
TYR C  51
PRO C  57
 ACT C1120
2J9D_A_ACTA1116 2j9d ACT

DB03166
(Acetic
acid) 		Methanocaldococcu
s jannaschii 		HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059 		None
PF00543
(P-II) 		9 LYS C   3
LYS A   3
LYS B   3
GLU A   5
GLU C   5
GLU B   5
ILE B  94
ILE C  94
ILE A  94
 ACT A1116
2J9D_A_ACTA1117 2j9d ACT

DB03166
(Acetic
acid) 		Methanocaldococcu
s jannaschii 		HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059 		None
PF00543
(P-II) 		3 ASP A  88
ARG C 101
ARG C 103
 ACT A1117
2J9D_E_ACTE1116 2j9d ACT

DB03166
(Acetic
acid) 		Methanocaldococcu
s jannaschii 		HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059 		None
PF00543
(P-II) 		10 LYS E   3
LYS F   3
LYS D   3
GLU E   5
GLU F   5
GLU D   5
GLU E  62
ILE D  94
ILE F  94
ILE E  94
 ACT E1116
2J9D_H_ACTH1113 2j9d ACT

DB03166
(Acetic
acid) 		Methanocaldococcu
s jannaschii 		HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059 		None 9 LYS I   3
LYS G   3
LYS H   3
GLU G   5
GLU I   5
GLU H   5
ILE I  94
ILE G  94
ILE H  94
 ACT H1113
2J9D_J_ACTJ1116 2j9d ACT

DB03166
(Acetic
acid) 		Methanocaldococcu
s jannaschii 		HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059 		None 8 LYS K   3
LYS L   3
LYS J   3
GLU K   5
GLU J   5
GLU L   5
ILE K  94
ILE J  94
 ACT J1116
2QQC_A_AG2A671 2qqc AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC) 		PF01862
(PvlArgDC)
no annotation 		7 LEU C  31
ASP C  35
LEU C  38
ILE B  54
MET B 108
GLN B 109
ARG B 134
 AG2 A 671
2QQC_A_AG2A672 2qqc AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC) 		PF01862
(PvlArgDC)
no annotation 		7 LEU A  31
ASP A  35
LEU A  38
ILE F  54
MET F 108
GLN F 109
ARG F 134
 AG2 A 672
2QQC_E_AG2E671 2qqc AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC) 		no annotation 7 LEU E  31
ASP E  35
LEU E  38
GLY E  44
ILE D  54
GLN D 109
ARG D 134
 AG2 E 671
2QQC_I_AG2I671 2qqc AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC) 		no annotation 7 LEU G  31
ASP G  35
LEU G  38
ILE J  54
MET J 108
GLN J 109
ARG J 134
 AG2 I 671
2QQC_I_AG2I672 2qqc AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC) 		no annotation 7 LEU I  31
ASP I  35
LEU I  38
ILE L  54
MET L 108
GLN L 109
ARG L 134
 AG2 I 672
2QQC_K_AG2K671 2qqc AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC) 		no annotation 8 LEU K  31
ASP K  35
LEU K  38
GLY K  44
ILE H  54
MET H 108
GLN H 109
ARG H 134
 AG2 K 671
2QQD_A_AG2A671 2qqd AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC) 		PF01862
(PvlArgDC)
no annotation 		7 LEU A  31
ASP A  35
LEU A  38
ILE E  54
MET E 108
GLU E 109
ARG E 134
 AG2 A 671
2QQD_B_AG2B671 2qqd AG2

DB08838
(Agmatine) 		Methanocaldococcu
s jannaschii 		PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC) 		PF01862
(PvlArgDC) 		8 LEU C  31
ASP C  35
LEU C  38
GLY C  44
ILE B  54
MET B 108
GLU B 109
ARG B 134
 AG2 B 671
2ZZM_A_SAMA401 2zzm SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0883 		PF02475
(Met_10) 		15 ARG A 145
TYR A 177
LEU A 182
ARG A 186
PHE A 203
GLY A 205
PRO A 208
ASP A 223
ILE A 224
ASN A 225
ASP A 251
VAL A 252
ASN A 265
LEU A 266
PHE A 273
 SAM A 401
2ZZN_A_SAMA401 2zzn SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0883 		PF02475
(Met_10) 		14 ARG A 145
TYR A 177
LEU A 182
ARG A 186
PHE A 203
GLY A 205
PRO A 208
ASP A 223
ILE A 224
ASN A 225
ASP A 251
VAL A 252
ASN A 265
PHE A 273
 SAM A 401
2ZZN_B_SAMB402 2zzn SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0883 		None 14 PHE B 144
TYR B 177
PHE B 178
LEU B 182
ARG B 186
PHE B 203
GLY B 205
PRO B 208
ASP B 223
ILE B 224
ASN B 225
ASP B 251
ASN B 265
PHE B 273
 SAM B 402
3A27_A_SAMA250 3a27 SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ1557 		PF02475
(Met_10) 		15 MET A  78
SER A  80
ASN A  83
ARG A  87
PHE A 104
GLY A 106
TYR A 109
GLU A 127
LYS A 128
ASN A 129
ASP A 154
ASN A 155
ARG A 156
TYR A 171
PHE A 178
 SAM A 250
3AI9_X_SAMX501 3ai9 SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UPF0217 PROTEIN
MJ1640 		PF04013
(Methyltrn_RNA_2) 		9 LEU X 136
ILE X 155
GLY X 156
SER X 178
LEU X 179
SER X 180
GLU X 183
LEU X 184
CYS X 189
 SAM X 501
3AIA_A_SAMA206 3aia SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UPF0217 PROTEIN
MJ1640 		PF04013
(Methyltrn_RNA_2) 		6 LEU A 136
MET A 138
GLY A 156
LEU A 179
SER A 180
CYS A 189
 SAM A 206
3AIA_B_SAMB206 3aia SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UPF0217 PROTEIN
MJ1640 		None
PF04013
(Methyltrn_RNA_2) 		5 SER A  43
LEU B 136
GLY B 156
GLU B 183
CYS B 189
 SAM B 206
3AY0_A_ADNA401 3ay0 ADN

DB00640
(Adenosine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0883 		PF02475
(Met_10) 		10 TYR A 177
PHE A 203
ASP A 223
ILE A 224
ASN A 225
ALA A 228
ASP A 251
VAL A 252
LEU A 266
PHE A 273
 ADN A 401
3AY0_B_ADNB402 3ay0 ADN

DB00640
(Adenosine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0883 		no annotation 10 TYR B 177
PHE B 203
GLY B 205
ASP B 223
ILE B 224
ASN B 225
ASP B 251
VAL B 252
LEU B 266
PHE B 273
 ADN B 402
3GRV_A_ADNA300 3grv ADN

DB00640
(Adenosine) 		Methanocaldococcu
s jannaschii 		DIMETHYLADENOSINE
TRANSFERASE 		PF00398
(RrnaAD) 		11 GLY A  38
GLY A  40
GLU A  59
ILE A  60
ASP A  61
LEU A  64
ASP A  84
ALA A  85
ASN A 101
PRO A 103
ILE A 106
 ADN A 300
3GRY_A_SAMA300 3gry SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		DIMETHYLADENOSINE
TRANSFERASE 		PF00398
(RrnaAD) 		12 LEU A  13
GLU A  36
GLY A  38
GLY A  40
GLU A  59
ILE A  60
ASP A  61
LEU A  64
ASP A  84
ALA A  85
ASN A 101
PRO A 103
 SAM A 300
3KPB_A_SAMA1000 3kpb SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0100 		PF00571
(CBS) 		12 ASN A 420
ILE A 434
THR A 436
TRP A 438
ASP A 439
LYS A 442
THR A 456
VAL A 459
ILE A 460
ILE A 480
SER A 481
PRO A 484
 SAM A1000
3KPB_C_SAMC1000 3kpb SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0100 		None 14 ASN D 418
ASN D 420
HIS C 421
ILE C 434
THR C 436
TRP C 438
ASP C 439
LYS C 442
THR C 456
VAL C 459
ILE C 460
ILE C 480
SER C 481
PRO C 484
 SAM C1000
3KPB_D_SAMD1000 3kpb SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0100 		None 10 ILE D 434
THR D 436
TRP D 438
ASP D 439
LYS D 442
THR D 456
VAL D 459
ILE D 460
ILE D 480
SER D 481
 SAM D1000
3KPC_A_SAMA1000 3kpc SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0100 		PF00571
(CBS) 		11 ILE A 434
THR A 436
TRP A 438
ASP A 439
THR A 456
VAL A 459
ILE A 460
ASN A 479
ILE A 480
SER A 481
PRO A 484
 SAM A1000
3KPD_B_SAMB1000 3kpd SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0100 		None 15 ASN C 418
ASN C 420
ILE B 434
THR B 436
TRP B 438
ASP B 439
LYS B 442
THR B 456
VAL B 459
ILE B 460
ASN B 479
ILE B 480
SER B 481
PRO B 484
GLU C 499
 SAM B1000
3KPD_C_SAMC1000 3kpd SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0100 		None 15 ASN B 418
ASN B 420
ILE C 434
THR C 436
TRP C 438
ASP C 439
THR C 456
VAL C 459
ILE C 460
ASN C 479
ILE C 480
SER C 481
VAL C 483
PRO C 484
GLU B 499
 SAM C1000
5D4U_A_SAMA301 5d4u SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0489 		PF06690
(DUF1188) 		16 LYS A  34
GLY A  54
TYR A  56
LEU A  57
TRP A  58
ASP A  77
ILE A  78
HIS A  79
MET A  82
LEU A  97
THR A 118
GLY A 122
GLU A 139
GLY A 184
THR A 185
PHE A 221
 SAM A 301
5D4U_B_SAMB301 5d4u SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0489 		None 16 LYS B  34
GLY B  54
TYR B  56
LEU B  57
TRP B  58
ASP B  77
ILE B  78
HIS B  79
MET B  82
LEU B  97
THR B 118
GLY B 122
GLU B 139
GLY B 184
THR B 185
PHE B 221
 SAM B 301
5D4U_C_SAMC301 5d4u SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0489 		None 16 LYS C  34
GLY C  54
TYR C  56
LEU C  57
TRP C  58
ASP C  77
ILE C  78
HIS C  79
MET C  82
LEU C  97
THR C 118
GLY C 122
ILE C 123
GLU C 139
GLY C 184
THR C 185
 SAM C 301
5D4U_D_SAMD301 5d4u SAM

DB00118
(S-
Adenosylmethionine) 		Methanocaldococcu
s jannaschii 		UNCHARACTERIZED
PROTEIN MJ0489 		None 16 LYS D  34
GLY D  54
TYR D  56
LEU D  57
TRP D  58
ASP D  77
ILE D  78
HIS D  79
MET D  82
LEU D  97
THR D 118
GLY D 122
ILE D 123
GLU D 139
GLY D 184
THR D 185
 SAM D 301