DRUG BINDING INTERFACES MAPPED TO 'Influenza A virus'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1L7F_A_BCZA801 | 1l7f | BCZ DB06614(Peramivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 15 | ARG A 118GLU A 119LEU A 134ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227GLU A 276GLU A 277ARG A 292ARG A 371TYR A 406 | BCZ A 801 |
1L7G_A_BCZA801 | 1l7g | BCZ DB06614(Peramivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 14 | ARG A 118LEU A 134ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227GLU A 276GLU A 277ARG A 292ARG A 371TYR A 406 | BCZ A 801 |
1L7H_A_BCZA801 | 1l7h | BCZ DB06614(Peramivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 15 | ARG A 118GLU A 119LEU A 134ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227GLU A 276GLU A 277LYS A 292ARG A 371TYR A 406 | BCZ A 801 |
1NNC_A_ZMRA479 | 1nnc | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE N9 | PF00064(Neur) | 16 | ARG A 118GLU A 119ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227ALA A 246GLU A 276GLU A 277ARG A 292ASN A 294ARG A 371TYR A 406 | ZMR A 479 |
2CML_A_ZMRA1477 | 2cml | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 17 | ARG A 124GLU A 125LEU A 140ASP A 157ARG A 158ARG A 162TRP A 185ILE A 229ARG A 231GLU A 234ALA A 253GLU A 283GLU A 284ARG A 299ASN A 301ARG A 378TYR A 412 | ZMR A1477 |
2CML_A_ZMRA1478 | 2cml | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 7 | SER A 374ASP A 376SER A 377SER A 379ASN A 406GLN A 407TRP A 409 | ZMR A1478 |
2CML_B_ZMRB2477 | 2cml | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 17 | ARG B1124GLU B1125LEU B1140ASP B1157ARG B1158ARG B1162TRP B1185ILE B1229ARG B1231GLU B1234ALA B1253GLU B1283GLU B1284ARG B1299ASN B1301ARG B1378TYR B1412 | ZMR B2477 |
2CML_B_ZMRB2478 | 2cml | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 8 | SER B1374ASP B1376SER B1377SER B1379ASN B1406GLN B1407TRP B1409LYS B1440 | ZMR B2478 |
2CML_C_ZMRC3477 | 2cml | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 17 | ARG C2124GLU C2125LEU C2140ASP C2157ARG C2158ARG C2162TRP C2185ILE C2229ARG C2231GLU C2234ALA C2253GLU C2283GLU C2284ARG C2299ASN C2301ARG C2378TYR C2412 | ZMR C3477 |
2CML_C_ZMRC3478 | 2cml | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 8 | SER C2374ASP C2376SER C2377SER C2379ASN C2406GLN C2407TRP C2409LYS C2440 | ZMR C3478 |
2CML_D_ZMRD4477 | 2cml | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 17 | ARG D3124GLU D3125LEU D3140ASP D3157ARG D3158ARG D3162TRP D3185ILE D3229ARG D3231GLU D3234ALA D3253GLU D3283GLU D3284ARG D3299ASN D3301ARG D3378TYR D3412 | ZMR D4477 |
2CML_D_ZMRD4478 | 2cml | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 8 | SER D3374ASP D3376SER D3377SER D3379ASN D3406GLN D3407TRP D3409LYS D3440 | ZMR D4478 |
2HTQ_A_ZMRA472 | 2htq | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 16 | ARG A 118GLU A 119ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227ALA A 246GLU A 276GLU A 277ARG A 292TYR A 347ARG A 371TYR A 406 | ZMR A 472 |
2HTU_A_BCZA801 | 2htu | BCZ DB06614(Peramivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 16 | ARG A 118GLU A 119LEU A 134ASP A 151ARG A 152ARG A 156TRP A 180SER A 181ILE A 224ARG A 226GLU A 229GLU A 278ARG A 294TYR A 352ARG A 376TYR A 411 | BCZ A 801 |
2KAD_A_308A1 | 2kad | 308 DB00915(Amantadine) | Influenza A virus | TRANSMEMBRANEPEPTIDE OF MATRIXPROTEIN 2 | PF00599(Flu_M2)no annotation | 9 | SER A 31SER D 31SER C 31SER B 31GLY D 34GLY A 34ILE A 35LEU B 38LEU C 38 | 308 A 1 |
2KQT_C_308C1 | 2kqt | 308 DB00915(Amantadine) | Influenza A virus | M2 PROTEIN | PF00599(Flu_M2)no annotation | 8 | ALA B 30ALA C 30ALA D 30ALA A 30SER D 31SER A 31SER C 31SER B 31 | 308 C 1 |
2LJC_A_RIMA1 | 2ljc | RIM DB00478(Rimantadine) | Influenza Avirus;Influenza B virus | M2 PROTEIN, BM2PROTEIN CHIMERA | PF00599(Flu_M2)PF04772(Flu_B_M2)no annotation | 10 | VAL B 27VAL D 27VAL A 27ALA B 30ALA C 30ALA D 30ALA A 30SER D 31SER A 31SER C 31 | RIM A 1 |
2RLF_A_RIMA199 | 2rlf | RIM DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | PF00599(Flu_M2)no annotation | 6 | LEU A 40TRP B 41ILE B 42LEU A 43ASP A 44ARG B 45 | RIM A 199 |
2RLF_B_RIMB299 | 2rlf | RIM DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | no annotation | 6 | LEU B 40TRP C 41ILE C 42LEU B 43ASP B 44ARG C 45 | RIM B 299 |
2RLF_C_RIMC399 | 2rlf | RIM DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | no annotation | 6 | LEU C 40TRP D 41ILE D 42LEU C 43ASP C 44ARG D 45 | RIM C 399 |
2RLF_D_RIMD499 | 2rlf | RIM DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | PF00599(Flu_M2)no annotation | 6 | LEU D 40TRP A 41ILE A 42ASP D 44ARG A 45LEU A 46 | RIM D 499 |
2Z0A_A_GLYA73 | 2z0a | GLY DB00145(Glycine) | Influenza A virus | NONSTRUCTURALPROTEIN 1 | PF00600(Flu_NS1) | 5 | GLN A 10ALA A 60GLN A 63ILE A 64ARG A 67 | GLY A 73 |
2Z0A_A_GLYA74 | 2z0a | GLY DB00145(Glycine) | Influenza A virus | NONSTRUCTURALPROTEIN 1 | PF00600(Flu_NS1) | 4 | LYS A 20LEU A 36ARG A 37GLN A 40 | GLY A 74 |
2Z0A_C_GLYC73 | 2z0a | GLY DB00145(Glycine) | Influenza A virus | NONSTRUCTURALPROTEIN 1 | None | 4 | ASP C 12ASP C 39SER C 42ARG C 46 | GLY C 73 |
2Z0A_D_GLYD73 | 2z0a | GLY DB00145(Glycine) | Influenza A virus | NONSTRUCTURALPROTEIN 1 | None | 4 | ARG C 35ASP D 39SER D 42ARG D 46 | GLY D 73 |
3B7E_A_ZMRA1001 | 3b7e | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 16 | ARG A 118GLU A 119ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227SER A 246GLU A 276GLU A 277ARG A 292ASN A 294ARG A 371TYR A 406 | ZMR A1001 |
3B7E_B_ZMRB1002 | 3b7e | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 16 | ARG B 118GLU B 119ASP B 151ARG B 152ARG B 156TRP B 178ILE B 222ARG B 224GLU B 227SER B 246GLU B 276GLU B 277ARG B 292ASN B 294ARG B 371TYR B 406 | ZMR B1002 |
3C9J_B_308B101 | 3c9j | 308 DB00915(Amantadine) | Influenza A virus | PROTON CHANNELPROTEIN M2,TRANSMEMBRANESEGMENT | PF00599(Flu_M2)no annotation | 6 | ALA A 9SER C 10SER A 10SER D 10SER B 10ALA B 13 | 308 B 101 |
3CKZ_A_ZMRA469 | 3ckz | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 18 | ARG A 118GLU A 119ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227SER A 246TYR A 274GLU A 276GLU A 277ARG A 292ASN A 294TYR A 347ARG A 371TYR A 406 | ZMR A 469 |
3SAN_A_ZMRA901 | 3san | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 17 | ARG A 118GLU A 119ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227ALA A 246GLU A 276GLU A 277ARG A 292ASN A 294TYR A 347ARG A 371TYR A 406 | ZMR A 901 |
3SAN_B_ZMRB901 | 3san | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 17 | ARG B 118GLU B 119ASP B 151ARG B 152ARG B 156TRP B 178ILE B 222ARG B 224GLU B 227ALA B 246GLU B 276GLU B 277ARG B 292ASN B 294TYR B 347ARG B 371TYR B 406 | ZMR B 901 |
3TI5_A_ZMRA1002 | 3ti5 | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 16 | ARG A 118GLU A 119ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227SER A 246GLU A 276GLU A 277ARG A 292ASN A 294ARG A 371TYR A 406 | ZMR A1002 |
3TI5_B_ZMRB1002 | 3ti5 | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 16 | ARG B 118GLU B 119ASP B 151ARG B 152ARG B 156TRP B 178ILE B 222ARG B 224GLU B 227SER B 246GLU B 276GLU B 277ARG B 292ASN B 294ARG B 371TYR B 406 | ZMR B1002 |
3TIC_A_ZMRA1002 | 3tic | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 17 | ARG A 118GLU A 119LEU A 134ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227ALA A 246GLU A 276GLU A 277ARG A 292ASN A 294ARG A 371TYR A 406 | ZMR A1002 |
3TIC_B_ZMRB1002 | 3tic | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 16 | ARG B 118GLU B 119ASP B 151ARG B 152ARG B 156TRP B 178ILE B 222ARG B 224GLU B 227ALA B 246GLU B 276GLU B 277ARG B 292ASN B 294ARG B 371TYR B 406 | ZMR B1002 |
3TIC_C_ZMRC1002 | 3tic | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 16 | ARG C 118GLU C 119ASP C 151ARG C 152ARG C 156TRP C 178ILE C 222ARG C 224GLU C 227ALA C 246GLU C 276GLU C 277ARG C 292ASN C 294ARG C 371TYR C 406 | ZMR C1002 |
3TIC_D_ZMRD1002 | 3tic | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 17 | ARG D 118GLU D 119LEU D 134ASP D 151ARG D 152ARG D 156TRP D 178ILE D 222ARG D 224GLU D 227ALA D 246GLU D 276GLU D 277ARG D 292ASN D 294ARG D 371TYR D 406 | ZMR D1002 |
4B7N_A_ZMRA601 | 4b7n | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 15 | ARG A 118GLU A 119ASP A 151ARG A 152ARG A 156TRP A 179ARG A 225GLU A 228SER A 247GLU A 277GLU A 278ARG A 293ASN A 295ARG A 368TYR A 402 | ZMR A 601 |
4B7Q_A_ZMRA601 | 4b7q | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 15 | ARG A 118GLU A 119ASP A 151ARG A 152ARG A 156ILE A 223ARG A 225GLU A 228SER A 247GLU A 277GLU A 278ARG A 293ASN A 295ARG A 368TYR A 402 | ZMR A 601 |
4B7Q_B_ZMRB601 | 4b7q | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 16 | ARG B 118GLU B 119LEU B 134ASP B 151ARG B 152ARG B 156TRP B 179ARG B 225GLU B 228SER B 247GLU B 277GLU B 278ARG B 293ASN B 295ARG B 368TYR B 402 | ZMR B 601 |
4B7Q_C_ZMRC601 | 4b7q | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 15 | ARG C 118GLU C 119ASP C 151ARG C 152ARG C 156ILE C 223ARG C 225GLU C 228SER C 247GLU C 277GLU C 278ARG C 293ASN C 295ARG C 368TYR C 402 | ZMR C 601 |
4B7Q_D_ZMRD601 | 4b7q | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | no annotation | 16 | ARG D 118GLU D 119ASP D 151ARG D 152ARG D 156TRP D 179ILE D 223ARG D 225GLU D 228SER D 247GLU D 277GLU D 278ARG D 293ASN D 295ARG D 368TYR D 402 | ZMR D 601 |
4I00_A_ZMRA509 | 4i00 | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 17 | ARG A 118GLU A 119LEU A 134ASP A 151ARG A 152ARG A 156TRP A 178ILE A 222ARG A 224GLU A 227ALA A 246GLU A 276GLU A 277ARG A 292ASN A 294ARG A 371TYR A 406 | ZMR A 509 |
4MWR_A_ZMRA513 | 4mwr | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 17 | ARG A 119GLU A 120LEU A 135ASP A 152ARG A 153ARG A 157TRP A 180ILE A 224ARG A 226GLU A 229ALA A 248GLU A 278GLU A 279ARG A 294ASN A 296ARG A 372TYR A 406 | ZMR A 513 |
4MWV_A_BCZA513 | 4mwv | BCZ DB06614(Peramivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 15 | ARG A 119GLU A 120LEU A 135ASP A 152ARG A 153ARG A 157TRP A 180ILE A 224ARG A 226GLU A 229GLU A 278GLU A 279ARG A 294ARG A 372TYR A 406 | BCZ A 513 |
4MWX_A_ZMRA513 | 4mwx | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 15 | ARG A 119GLU A 120ASP A 152ARG A 153ARG A 157TRP A 180ILE A 224ARG A 226GLU A 229ALA A 248GLU A 278GLU A 279LYS A 294ARG A 372TYR A 406 | ZMR A 513 |
4MX0_A_BCZA513 | 4mx0 | BCZ DB06614(Peramivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 15 | ARG A 119GLU A 120LEU A 135ASP A 152ARG A 153ARG A 157TRP A 180SER A 181ARG A 226GLU A 229ALA A 248GLU A 278GLU A 279ARG A 372TYR A 406 | BCZ A 513 |
4WA5_A_ZMRA501 | 4wa5 | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 17 | ARG A 116GLU A 117ASP A 149ARG A 150ARG A 154TRP A 177ILE A 221ARG A 223GLU A 226ALA A 245GLU A 275GLU A 276ARG A 291ASN A 293TYR A 344ARG A 368TYR A 402 | ZMR A 501 |
5L17_A_ZMRA512 | 5l17 | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 16 | ARG A 119GLU A 120LEU A 135ASP A 152ARG A 153ARG A 157TRP A 180ILE A 224ARG A 226GLU A 229ALA A 248GLU A 278GLU A 279ARG A 294ARG A 372TYR A 406 | ZMR A 512 |
6BKK_B_308B101 | 6bkk | 308 DB00915(Amantadine) | Influenza A virus | MATRIX PROTEIN 2 | NonePF00599(Flu_M2) | 6 | VAL A 27ALA C 30SER A 31SER D 31SER C 31SER B 31 | 308 B 101 |
6BKK_F_308F101 | 6bkk | 308 DB00915(Amantadine) | Influenza A virus | MATRIX PROTEIN 2 | None | 6 | VAL E 27ALA F 30SER G 31SER F 31SER H 31SER E 31 | 308 F 101 |
6BKL_C_EU7C101 | 6bkl | EU7 DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | NonePF00599(Flu_M2) | 9 | VAL C 27VAL D 27ALA C 30ALA B 30SER A 31SER D 31SER C 31SER B 31GLY D 34 | EU7 C 101 |
6BKL_D_RIMD101 | 6bkl | RIM DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | NonePF00599(Flu_M2) | 9 | VAL D 27ALA C 30ALA B 30ALA D 30SER A 31SER D 31SER C 31SER B 31GLY A 34 | RIM D 101 |
6BKL_F_RIMF101 | 6bkl | RIM DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | None | 9 | ALA G 30ALA F 30ALA E 30SER G 31SER F 31SER H 31SER E 31GLY F 34GLY E 34 | RIM F 101 |
6BKL_G_EU7G101 | 6bkl | EU7 DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | None | 9 | ALA F 30ALA G 30ALA E 30SER G 31SER F 31SER H 31SER E 31GLY F 34GLY G 34 | EU7 G 101 |
6BOC_A_EU7A102 | 6boc | EU7 DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | NonePF00599(Flu_M2) | 6 | ALA C 30ALA D 30SER A 31SER D 31SER C 31SER B 31 | EU7 A 102 |
6BOC_C_RIMC101 | 6boc | RIM DB00478(Rimantadine) | Influenza A virus | MATRIX PROTEIN 2 | NonePF00599(Flu_M2) | 6 | ALA C 30ALA D 30SER A 31SER D 31SER C 31SER B 31 | RIM C 101 |
6HCX_A_ZMRA519 | 6hcx | ZMR DB00558(Zanamivir) | Influenza A virus | NEURAMINIDASE | PF00064(Neur) | 15 | ARG A 119GLU A 120ASP A 152ARG A 153ARG A 157TRP A 180ILE A 224ARG A 226GLU A 229ALA A 248GLU A 278GLU A 279ARG A 294ARG A 372TYR A 406 | ZMR A 519 |