DRUG BINDING INTERFACES MAPPED TO 'Helicobacter pylori'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1E9Y_B_HAEB800 | 1e9y | HAE DB00551(AcetohydroxamicAcid) | Helicobacterpylori | UREASE SUBUNIT BETA | PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | HIS B 136HIS B 221HIS B 248HIS B 274ASP B 362 | HAE B 800 |
2XRH_A_NIOA200 | 2xrh | NIO DB00627(Niacin) | Helicobacterpylori | PROTEIN HP0721 | PF06518(DUF1104) | 7 | GLY A 36ILE A 43THR A 47ARG A 88GLN A 89MET A 104LEU A 110 | NIO A 200 |
3UB9_A_NHYA301 | 3ub9 | NHY DB01005(Hydroxyurea) | Helicobacterpylori | CHEMORECEPTOR TLPB | PF17200(sCache_2) | 10 | VAL A 103ASP A 114VAL A 116ASN A 117TYR A 136TYR A 140TYR A 153MET A 155LYS A 166TYR A 185 | NHY A 301 |
3UB9_B_NHYB301 | 3ub9 | NHY DB01005(Hydroxyurea) | Helicobacterpylori | CHEMORECEPTOR TLPB | no annotation | 10 | VAL B 103ASP B 114VAL B 116ASN B 117TYR B 136TYR B 140TYR B 153MET B 155LYS B 166TYR B 185 | NHY B 301 |
4YGF_A_AZMA303 | 4ygf | AZM DB00819(Acetazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | PF00194(Carb_anhydrase) | 11 | LYS A 88ASN A 108HIS A 110HIS A 112HIS A 129VAL A 131VAL A 141LEU A 190THR A 191ALA A 192TRP A 201 | AZM A 303 |
4YGF_B_AZMB303 | 4ygf | AZM DB00819(Acetazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 11 | ASN B 108HIS B 110HIS B 112GLU B 116HIS B 129VAL B 131LYS B 133VAL B 141LEU B 190THR B 191TRP B 201 | AZM B 303 |
4YGF_C_AZMC303 | 4ygf | AZM DB00819(Acetazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 11 | LYS C 88ASN C 108HIS C 110HIS C 112HIS C 129VAL C 131VAL C 141LEU C 190THR C 191ALA C 192TRP C 201 | AZM C 303 |
4YGF_D_AZMD303 | 4ygf | AZM DB00819(Acetazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 11 | ASN D 108HIS D 110HIS D 112GLU D 116HIS D 129VAL D 131VAL D 141LEU D 190THR D 191ALA D 192TRP D 201 | AZM D 303 |
4YGF_E_AZME303 | 4ygf | AZM DB00819(Acetazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 12 | LYS E 88ASN E 108HIS E 110HIS E 112GLU E 116HIS E 129VAL E 131LYS E 133VAL E 141LEU E 190THR E 191TRP E 201 | AZM E 303 |
4YGF_F_AZMF303 | 4ygf | AZM DB00819(Acetazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 9 | ASN F 108HIS F 110HIS F 112HIS F 129VAL F 131VAL F 141LEU F 190THR F 191TRP F 201 | AZM F 303 |
4YGF_G_AZMG303 | 4ygf | AZM DB00819(Acetazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 12 | LYS G 88ASN G 108HIS G 110HIS G 112HIS G 129VAL G 131LYS G 133VAL G 141LEU G 190THR G 191ALA G 192TRP G 201 | AZM G 303 |
4YGF_H_AZMH303 | 4ygf | AZM DB00819(Acetazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 9 | ASN H 108HIS H 110HIS H 112HIS H 129VAL H 131VAL H 141LEU H 190THR H 191TRP H 201 | AZM H 303 |
4YHA_A_MZMA303 | 4yha | MZM DB00703(Methazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | PF00194(Carb_anhydrase) | 12 | LYS A 88ASP A 107ASN A 108HIS A 110HIS A 112HIS A 129VAL A 131VAL A 141LEU A 190THR A 191ALA A 192TRP A 201 | MZM A 303 |
4YHA_B_MZMB303 | 4yha | MZM DB00703(Methazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 10 | ASP B 107ASN B 108HIS B 110HIS B 112HIS B 129VAL B 131VAL B 141LEU B 190THR B 191ALA B 192 | MZM B 303 |
4YHA_C_MZMC303 | 4yha | MZM DB00703(Methazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 11 | LYS C 88ASP C 107ASN C 108HIS C 110HIS C 112HIS C 129VAL C 131VAL C 141LEU C 190THR C 191TRP C 201 | MZM C 303 |
4YHA_D_MZMD302 | 4yha | MZM DB00703(Methazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 11 | LYS D 88ASN D 108HIS D 110HIS D 112GLU D 116HIS D 129VAL D 131LEU D 190THR D 191ALA D 192TRP D 201 | MZM D 302 |
4YHA_E_MZME303 | 4yha | MZM DB00703(Methazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 13 | LYS E 88ASN E 108HIS E 110HIS E 112GLU E 116HIS E 129VAL E 131VAL E 141LEU E 190THR E 191ALA E 192PRO E 194TRP E 201 | MZM E 303 |
4YHA_F_MZMF302 | 4yha | MZM DB00703(Methazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 10 | ASP F 107ASN F 108HIS F 110HIS F 112HIS F 129VAL F 131LEU F 190THR F 191ALA F 192TRP F 201 | MZM F 302 |
4YHA_G_MZMG303 | 4yha | MZM DB00703(Methazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 12 | LYS G 88ASN G 108HIS G 110HIS G 112HIS G 129VAL G 131LYS G 133VAL G 141LEU G 190THR G 191ALA G 192TRP G 201 | MZM G 303 |
4YHA_H_MZMH303 | 4yha | MZM DB00703(Methazolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 10 | ASN H 108HIS H 110HIS H 112GLU H 116HIS H 129VAL H 131LEU H 190THR H 191ALA H 192TRP H 201 | MZM H 303 |
5FXT_A_0LAA1376 | 5fxt | 0LA DB00821(Carprofen) | Helicobacterpylori | DNA POLYMERASE IIISUBUNIT BETA | PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 7 | LYS A 152LEU A 155THR A 174PRO A 244ILE A 249LEU A 369MET A 371 | 0LA A1376 |
5G48_A_1FLA1375 | 5g48 | 1FL DB00861(Diflunisal) | Helicobacterpylori | DNA POLYMERASE IIISUBUNIT BETA | PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 8 | THR A 173THR A 175LEU A 178PRO A 243ILE A 248PRO A 347LEU A 368MET A 370 | 1FL A1375 |
5G48_B_1FLB1375 | 5g48 | 1FL DB00861(Diflunisal) | Helicobacterpylori | DNA POLYMERASE IIISUBUNIT BETA | no annotation | 9 | LEU B 154THR B 173THR B 175LEU B 178PRO B 243ILE B 248PRO B 347LEU B 368MET B 370 | 1FL B1375 |
5HFJ_A_SAMA301 | 5hfj | SAM DB00118(S-Adenosylmethionine) | Helicobacterpylori | ADENINE SPECIFIC DNAMETHYLTRANSFERASE(DPNA) | PF01555(N6_N4_Mtase) | 14 | ASP A 8ALA A 9ASP A 29PRO A 31LYS A 165LYS A 167PHE A 195GLY A 197SER A 198THR A 200GLU A 216SER A 217GLU A 218TYR A 221 | SAM A 301 |
5HFJ_B_SAMB301 | 5hfj | SAM DB00118(S-Adenosylmethionine) | Helicobacterpylori | ADENINE SPECIFIC DNAMETHYLTRANSFERASE(DPNA) | None | 14 | ASP B 8ALA B 9ASP B 29PRO B 31HIS B 168THR B 170GLN B 171PHE B 195GLY B 197SER B 198THR B 200GLU B 216SER B 217TYR B 221 | SAM B 301 |
5HFJ_C_SAMC301 | 5hfj | SAM DB00118(S-Adenosylmethionine) | Helicobacterpylori | ADENINE SPECIFIC DNAMETHYLTRANSFERASE(DPNA) | None | 16 | ASP C 8ALA C 9ASP C 29PRO C 31HIS C 168THR C 170GLN C 171LYS C 172PHE C 195GLY C 197SER C 198THR C 200GLU C 216SER C 217GLU C 218TYR C 221 | SAM C 301 |
5HFJ_D_SAMD301 | 5hfj | SAM DB00118(S-Adenosylmethionine) | Helicobacterpylori | ADENINE SPECIFIC DNAMETHYLTRANSFERASE(DPNA) | None | 12 | ASP D 8ALA D 9ASP D 29PRO D 31PHE D 195GLY D 197SER D 198THR D 200GLU D 216SER D 217GLU D 218TYR D 221 | SAM D 301 |
5HFJ_E_SAME301 | 5hfj | SAM DB00118(S-Adenosylmethionine) | Helicobacterpylori | ADENINE SPECIFIC DNAMETHYLTRANSFERASE(DPNA) | None | 12 | ASP E 8ALA E 9ASP E 29PRO E 169LYS E 172PHE E 195GLY E 197SER E 198THR E 200GLU E 216SER E 217TYR E 221 | SAM E 301 |
5HFJ_F_SAMF301 | 5hfj | SAM DB00118(S-Adenosylmethionine) | Helicobacterpylori | ADENINE SPECIFIC DNAMETHYLTRANSFERASE(DPNA) | None | 12 | ASP F 8ALA F 9ASP F 29PRO F 31THR F 170GLN F 171PHE F 195GLY F 197SER F 198GLU F 216SER F 217TYR F 221 | SAM F 301 |
5HFJ_G_SAMG301 | 5hfj | SAM DB00118(S-Adenosylmethionine) | Helicobacterpylori | ADENINE SPECIFIC DNAMETHYLTRANSFERASE(DPNA) | None | 16 | ASP G 8ALA G 9ASP G 29PRO G 31HIS G 168THR G 170GLN G 171LYS G 172PHE G 195GLY G 197SER G 198THR G 200GLU G 216SER G 217GLU G 218TYR G 221 | SAM G 301 |
5HFJ_H_SAMH301 | 5hfj | SAM DB00118(S-Adenosylmethionine) | Helicobacterpylori | ADENINE SPECIFIC DNAMETHYLTRANSFERASE(DPNA) | None | 14 | ASP H 8ALA H 9ASP H 29PRO H 31THR H 170GLN H 171LYS H 172PHE H 195GLY H 197SER H 198THR H 200GLU H 216SER H 217TYR H 221 | SAM H 301 |
5TT3_A_EZLA303 | 5tt3 | EZL DB00311(Ethoxzolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | PF00194(Carb_anhydrase) | 10 | HIS A 110HIS A 112HIS A 129VAL A 131VAL A 141LEU A 190THR A 191ALA A 192PRO A 194TRP A 201 | EZL A 303 |
5TT3_B_EZLB303 | 5tt3 | EZL DB00311(Ethoxzolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 9 | HIS B 110HIS B 112HIS B 129VAL B 131VAL B 141LEU B 190THR B 191ALA B 192TRP B 201 | EZL B 303 |
5TT3_C_EZLC303 | 5tt3 | EZL DB00311(Ethoxzolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 10 | HIS C 110HIS C 112HIS C 129VAL C 131VAL C 141LEU C 190THR C 191ALA C 192PRO C 194TRP C 201 | EZL C 303 |
5TT3_E_EZLE303 | 5tt3 | EZL DB00311(Ethoxzolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 9 | HIS E 110HIS E 112HIS E 129VAL E 131VAL E 141LEU E 190THR E 191ALA E 192TRP E 201 | EZL E 303 |
5TT3_F_EZLF302 | 5tt3 | EZL DB00311(Ethoxzolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 8 | HIS F 110HIS F 112HIS F 129VAL F 131VAL F 141LEU F 190THR F 191TRP F 201 | EZL F 302 |
5TT3_G_EZLG303 | 5tt3 | EZL DB00311(Ethoxzolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 9 | HIS G 110HIS G 112HIS G 129VAL G 131VAL G 141LEU G 190THR G 191ALA G 192TRP G 201 | EZL G 303 |
5TT3_H_EZLH303 | 5tt3 | EZL DB00311(Ethoxzolamide) | Helicobacterpylori | ALPHA-CARBONICANHYDRASE | no annotation | 8 | HIS H 110HIS H 112HIS H 129VAL H 131LEU H 190THR H 191ALA H 192TRP H 201 | EZL H 303 |