DRUG BINDING INTERFACES MAPPED TO 'Drosophila melanogaster'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
Filter list by:
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1J36_A_LPRA801 1j36 LPR

DB00722
(Lisinopril)
Drosophila
melanogaster
ANGIOTENSIN
CONVERTING ENZYME
PF01401
(Peptidase_M2)
16 ARG A  51
GLN A 265
HIS A 337
ALA A 338
SER A 339
THR A 364
HIS A 367
GLU A 368
HIS A 371
GLU A 395
LYS A 495
TYR A 496
HIS A 497
VAL A 502
TYR A 504
TYR A 507
LPR A 801
1J36_B_LPRB802 1j36 LPR

DB00722
(Lisinopril)
Drosophila
melanogaster
ANGIOTENSIN
CONVERTING ENZYME
no annotation 16 ARG B  51
GLN B 265
HIS B 337
ALA B 338
SER B 339
THR B 364
HIS B 367
GLU B 368
HIS B 371
GLU B 395
LYS B 495
TYR B 496
HIS B 497
VAL B 502
TYR B 504
TYR B 507
LPR B 802
1J37_A_X8ZA801 1j37 X8Z

DB01197
(Captopril)
Drosophila
melanogaster
ANGIOTENSIN
CONVERTING ENZYME
PF01401
(Peptidase_M2)
11 GLN A 265
HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 441
LYS A 495
HIS A 497
TYR A 504
TYR A 507
X8Z A 801
1J37_B_X8ZB802 1j37 X8Z

DB01197
(Captopril)
Drosophila
melanogaster
ANGIOTENSIN
CONVERTING ENZYME
no annotation 11 GLN B 265
HIS B 337
HIS B 367
GLU B 368
HIS B 371
GLU B 395
PHE B 441
LYS B 495
HIS B 497
TYR B 504
TYR B 507
X8Z B 802
2JJ8_A_AZZA1211 2jj8 AZZ

DB00495
(Zidovudine)
Drosophila
melanogaster
DEOXYNUCLEOSIDE
KINASE
PF01712
(dNK)
10 GLU A  52
VAL A  54
TRP A  57
PHE A  80
GLN A  81
VAL A  84
MET A  88
ARG A 105
ALA A 110
PHE A 114
AZZ A1211
2JJ8_B_AZZB1211 2jj8 AZZ

DB00495
(Zidovudine)
Drosophila
melanogaster
DEOXYNUCLEOSIDE
KINASE
no annotation 12 GLU B  52
TRP B  57
LEU B  66
TYR B  70
PHE B  80
GLN B  81
VAL B  84
MET B  88
ARG B 105
ALA B 110
PHE B 114
MET B 118
AZZ B1211
2JJ8_C_AZZC1211 2jj8 AZZ

DB00495
(Zidovudine)
Drosophila
melanogaster
DEOXYNUCLEOSIDE
KINASE
no annotation 12 ILE C  29
GLU C  52
VAL C  54
TRP C  57
LEU C  66
MET C  69
PHE C  80
GLN C  81
ARG C 105
ALA C 110
PHE C 114
MET C 118
AZZ C1211
2JJ8_D_AZZD1211 2jj8 AZZ

DB00495
(Zidovudine)
Drosophila
melanogaster
DEOXYNUCLEOSIDE
KINASE
no annotation 10 ILE D  29
GLU D  52
TRP D  57
PHE D  80
GLN D  81
VAL D  84
MET D  88
ARG D 105
ALA D 110
PHE D 114
AZZ D1211
2VPP_A_GEOA1210 2vpp GEO

DB00441
(Gemcitabine)
Drosophila
melanogaster
DEOXYNUCLEOSIDE
KINASE
PF01712
(dNK)
13 ILE A  29
GLU A  52
VAL A  54
TRP A  57
MET A  69
TYR A  70
PHE A  80
GLN A  81
VAL A  84
ARG A 105
ALA A 110
PHE A 114
GLU A 172
GEO A1210
2VPP_B_GEOB1207 2vpp GEO

DB00441
(Gemcitabine)
Drosophila
melanogaster
DEOXYNUCLEOSIDE
KINASE
no annotation 14 ILE B  29
GLU B  52
VAL B  54
TRP B  57
LEU B  66
MET B  69
TYR B  70
PHE B  80
GLN B  81
VAL B  84
ARG B 105
ALA B 110
PHE B 114
GLU B 172
GEO B1207
2X8Z_A_X8ZA1615 2x8z X8Z

DB01197
(Captopril)
Drosophila
melanogaster
ANGIOTENSIN
CONVERTING ENZYME
PF01401
(Peptidase_M2)
11 GLN A 265
HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 441
LYS A 495
HIS A 497
TYR A 504
TYR A 507
X8Z A1615
2X91_A_LPRA1615 2x91 LPR

DB00722
(Lisinopril)
Drosophila
melanogaster
ANGIOTENSIN
CONVERTING ENZYME
PF01401
(Peptidase_M2)
15 GLN A 265
HIS A 337
SER A 339
THR A 364
HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 441
LYS A 495
TYR A 496
HIS A 497
VAL A 502
TYR A 504
TYR A 507
LPR A1615
4M48_A_21BA704 4m48 21B

DB00540
(Nortriptyline)
Drosophila
melanogaster
TRANSPORTER PF00209
(SNF)
8 PHE A  43
ASP A  46
VAL A 120
ASP A 121
TYR A 124
SER A 421
GLY A 425
ALA A 479
21B A 704
4XNX_A_41XA707 4xnx 41X

DB00234
(Reboxetine)
Drosophila
melanogaster
TRANSPORTER PF00209
(SNF)
11 PHE A  43
ASP A  46
ALA A 117
VAL A 120
ASP A 121
TYR A 123
TYR A 124
GLY A 322
VAL A 327
SER A 421
GLY A 425
41X A 707
4XP1_A_LDPA708 4xp1 LDP

DB00988
(Dopamine)
Drosophila
melanogaster
DOPAMINE
TRANSPORTER, ISOFORM
B
PF00209
(SNF)
10 PHE A  43
ASP A  46
ALA A 117
VAL A 120
ASP A 121
TYR A 124
PHE A 325
SER A 421
SER A 422
GLY A 425
LDP A 708
4XP4_A_COCA706 4xp4 COC

DB00907
(Cocaine)
Drosophila
melanogaster
DOPAMINE TRANSPORTER PF00209
(SNF)
11 PHE A  43
ASP A  46
ALA A  48
VAL A 120
ASP A 121
TYR A 123
TYR A 124
GLY A 322
PHE A 325
SER A 421
GLY A 425
COC A 706
4XP6_A_B40A601 4xp6 B40

DB01577
(Methamphetamine)
Drosophila
melanogaster
TRANSPORTER PF00209
(SNF)
5 ASP A  46
VAL A 120
ASP A 121
PHE A 325
GLY A 425
B40 A 601
4XP9_C_1WEC706 4xp9 1WE

DB00182
(Amphetamine)
DB01576
(Dextroamphetamine)
Drosophila
melanogaster
TRANSPORTER PF00209
(SNF)
4 PHE C  43
ASP C  46
GLY C 322
SER C 421
1WE C 706
4XPB_A_COCA702 4xpb COC

DB00907
(Cocaine)
Drosophila
melanogaster
TRANSPORTER PF00209
(SNF)
10 PHE A  43
ASP A  46
VAL A 120
TYR A 123
TYR A 124
GLY A 322
PHE A 325
SER A 421
GLY A 425
MET A 426
COC A 702
5G08_A_Z80A1187 5g08 Z80

DB00477
(Chlorpromazine)
Drosophila
melanogaster
FREQUENIN 2 PF00036
(EF-hand_1)
PF13499
(EF-hand_7)
6 ILE A  51
TYR A  52
PHE A  55
PHE A  72
THR A  92
TRP A 103
Z80 A1187
5KLA_A_ACTA1505 5kla ACT

DB03166
(Acetic
acid)
Drosophila
melanogaster
MATERNAL PROTEIN
PUMILIO
PF00806
(PUF)
3 HIS A1338
LYS A1339
PHE A1340
ACT A1505
5VKQ_A_PCFA1801 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
6 ILE A1271
ILE A1416
LEU A1420
PHE A1422
HIS A1423
PHE B1452
PCF A1801
5VKQ_A_PCFA1803 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
10 HIS D1492
ILE D1494
ASN D1495
GLU D1498
TYR A1528
TYR A1532
LYS A1535
ILE A1536
ILE A1540
LEU A1543
PCF A1803
5VKQ_A_PCFA1804 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
5 TRP A1394
THR A1396
ASN B1467
TRP B1529
LEU B1533
PCF A1804
5VKQ_A_PCFA1805 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
7 SER D1319
THR D1324
PHE A1486
VAL A1489
HIS A1492
PRO A1493
ILE A1494
PCF A1805
5VKQ_A_PCFA1807 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
7 GLY A1363
LEU A1364
LEU A1410
ILE A1433
GLY A1434
LEU A1437
ILE B1540
PCF A1807
5VKQ_A_PCFA1808 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
5 LEU D1425
LEU A1437
LYS A1438
ALA A1441
LEU A1444
PCF A1808
5VKQ_B_PCFB1801 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 5 TRP B1394
THR B1396
ASN C1467
TRP C1529
LEU C1533
PCF B1801
5VKQ_B_PCFB1802 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
7 SER A1319
THR A1324
PHE B1486
VAL B1489
HIS B1492
PRO B1493
ILE B1494
PCF B1802
5VKQ_B_PCFB1804 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 8 GLY B1363
LEU B1364
LEU B1410
VAL B1414
ILE B1433
GLY B1434
LEU B1437
ILE C1540
PCF B1804
5VKQ_B_PCFB1805 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
5 LEU A1425
LEU B1437
LYS B1438
ALA B1441
LEU B1444
PCF B1805
5VKQ_B_PCFB1806 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 6 ILE B1271
ILE B1416
LEU B1420
PHE B1422
HIS B1423
PHE C1452
PCF B1806
5VKQ_B_PCFB1808 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
10 HIS A1492
ILE A1494
ASN A1495
GLU A1498
TYR B1528
TYR B1532
LYS B1535
ILE B1536
ILE B1540
LEU B1543
PCF B1808
5VKQ_C_PCFC1801 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 9 HIS B1492
ILE B1494
GLU B1498
TYR C1528
TYR C1532
LYS C1535
ILE C1536
ILE C1540
LEU C1543
PCF C1801
5VKQ_C_PCFC1802 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 5 TRP C1394
THR C1396
ASN D1467
TRP D1529
LEU D1533
PCF C1802
5VKQ_C_PCFC1803 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 8 SER B1319
THR B1324
PHE C1452
PHE C1486
VAL C1489
HIS C1492
PRO C1493
ILE C1494
PCF C1803
5VKQ_C_PCFC1805 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 9 GLY C1363
LEU C1364
LEU C1410
VAL C1414
ILE C1433
GLY C1434
LEU C1437
PHE D1454
ILE D1540
PCF C1805
5VKQ_C_PCFC1806 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 5 LEU B1425
LEU C1437
LYS C1438
ALA C1441
LEU C1444
PCF C1806
5VKQ_C_PCFC1807 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 6 ILE C1271
ILE C1416
LEU C1420
PHE C1422
HIS C1423
PHE D1452
PCF C1807
5VKQ_D_PCFD1801 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 10 HIS C1492
ILE C1494
ASN C1495
GLU C1498
TYR D1528
TYR D1532
LYS D1535
ILE D1536
ILE D1540
LEU D1543
PCF D1801
5VKQ_D_PCFD1802 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
4 TRP D1394
THR D1396
ASN A1467
LEU A1533
PCF D1802
5VKQ_D_PCFD1803 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 7 SER C1319
THR C1324
PHE D1486
VAL D1489
HIS D1492
PRO D1493
ILE D1494
PCF D1803
5VKQ_D_PCFD1805 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
7 GLY D1363
LEU D1364
LEU D1410
ILE D1433
GLY D1434
LEU D1437
ILE A1540
PCF D1805
5VKQ_D_PCFD1806 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 5 LEU C1425
LEU D1437
LYS D1438
ALA D1441
LEU D1444
PCF D1806
5VKQ_D_PCFD1807 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
6 ILE D1271
ILE D1416
LEU D1420
PHE D1422
HIS D1423
PHE A1452
PCF D1807
6DYN_A_HSMA901 6dyn HSM

DB05381
(Histamine)
Drosophila
melanogaster
EBONY None 4 GLU A 696
VAL A 760
LEU A 764
THR A 828
HSM A 901
6DYO_A_LDPA901 6dyo LDP

DB00988
(Dopamine)
Drosophila
melanogaster
EBONY None 5 GLU A 696
VAL A 760
LEU A 764
HIS A 785
THR A 828
LDP A 901