DRUG BINDING INTERFACES MAPPED TO 'Bacteroides thetaiotaomicron'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
2OKC_A_SAMA500 | 2okc | SAM DB00118(S-Adenosylmethionine) | Bacteroidesthetaiotaomicron | TYPE I RESTRICTIONENZYME STYSJI MPROTEIN | PF02384(HsdM_N)PF12161(N6_Mtase) | 18 | TYR A 152THR A 154ARG A 156ILE A 159ALA A 178GLY A 180THR A 181GLY A 183ASP A 214ASN A 215THR A 216VAL A 219ASP A 243SER A 244ASN A 259PRO A 261ARG A 265PHE A 288 | SAM A 500 |
2OKC_B_SAMB500 | 2okc | SAM DB00118(S-Adenosylmethionine) | Bacteroidesthetaiotaomicron | TYPE I RESTRICTIONENZYME STYSJI MPROTEIN | None | 18 | TYR B 152THR B 154ARG B 156ILE B 159ALA B 178GLY B 180THR B 181GLY B 183ASP B 214ASN B 215THR B 216VAL B 219ASP B 243SER B 244ASN B 259PRO B 261ARG B 265PHE B 288 | SAM B 500 |
2W4X_A_STZA1591 | 2w4x | STZ DB00428(Streptozocin) | Bacteroidesthetaiotaomicron | O-GLCNACASE BT_4395 | PF02838(Glyco_hydro_20b)PF07555(NAGidase) | 11 | ASP A 242CYS A 278TYR A 282THR A 310VAL A 314TRP A 337ASN A 339VAL A 342ASP A 344TYR A 345ASN A 372 | STZ A1591 |
2Y6R_A_CTCA1385 | 2y6r | CTC DB09093(Chlortetracycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | PF01494(FAD_binding_3) | 10 | ASP A 61GLN A 192ARG A 213MET A 215PHE A 224ASN A 226GLY A 236PRO A 318GLY A 321MET A 375 | CTC A1385 |
2Y6R_B_CTCB1385 | 2y6r | CTC DB09093(Chlortetracycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | None | 8 | GLN B 192ARG B 213MET B 215PHE B 224GLY B 236PRO B 318GLY B 321MET B 375 | CTC B1385 |
2Y6R_C_CTCC1385 | 2y6r | CTC DB09093(Chlortetracycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | None | 12 | ASP C 61ASN C 190GLN C 192ARG C 213MET C 215PHE C 224HIS C 234GLY C 236SER C 238PRO C 318GLY C 321MET C 375 | CTC C1385 |
2Y6R_D_CTCD1385 | 2y6r | CTC DB09093(Chlortetracycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | None | 10 | ASP D 61GLN D 192ARG D 213MET D 215PHE D 224HIS D 234GLY D 236SER D 238PRO D 318MET D 375 | CTC D1385 |
2ZQ0_A_ACRA801 | 2zq0 | ACR DB00284(Acarbose) | Bacteroidesthetaiotaomicron | ALPHA-GLUCOSIDASE(ALPHA-GLUCOSIDASESUSB) | PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 21 | GLU A 194ASN A 216SER A 217TRP A 331ILE A 335TRP A 341GLU A 391TRP A 397TRP A 400PHE A 401HIS A 437GLU A 439LYS A 467VAL A 471HIS A 507GLU A 508GLU A 526GLU A 532TYR A 533PHE A 536GLY A 537 | ACR A 801 |
2ZQ0_B_ACRB811 | 2zq0 | ACR DB00284(Acarbose) | Bacteroidesthetaiotaomicron | ALPHA-GLUCOSIDASE(ALPHA-GLUCOSIDASESUSB) | no annotation | 21 | GLU B 194ASN B 216SER B 217TRP B 331ILE B 335TRP B 341GLU B 391TRP B 397TRP B 400PHE B 401HIS B 437GLU B 439LYS B 467VAL B 471HIS B 507GLU B 508GLU B 526GLU B 532TYR B 533PHE B 536GLY B 537 | ACR B 811 |
3CO4_A_GCSA401 | 3co4 | GCS DB01296(Glucosamine) | Bacteroidesthetaiotaomicron | CHITINASE | PF00704(Glyco_hydro_18) | 3 | GLU A 348HIS A 352HIS A 353 | GCS A 401 |
3K13_A_THHA642 | 3k13 | THH DB11256(Levomefolicacid) | Bacteroidesthetaiotaomicron | 5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINEMETHYLTRANSFERASE | PF00809(Pterin_bind) | 15 | GLU A 358ASN A 361GLY A 364ARG A 366ASP A 431ASN A 452VAL A 478ASP A 519GLY A 558SER A 560ASN A 561PHE A 564ARG A 567ARG A 573ILE A 593 | THH A 642 |
3K13_B_THHB643 | 3k13 | THH DB11256(Levomefolicacid) | Bacteroidesthetaiotaomicron | 5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINEMETHYLTRANSFERASE | None | 14 | GLU B 358ASN B 361GLY B 364ARG B 366ASP B 431ASN B 452VAL B 478ASP B 519GLY B 558SER B 560ASN B 561ARG B 567ARG B 573ILE B 593 | THH B 643 |
3K13_C_THHC643 | 3k13 | THH DB11256(Levomefolicacid) | Bacteroidesthetaiotaomicron | 5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINEMETHYLTRANSFERASE | None | 15 | GLU C 358ASN C 361GLY C 364ARG C 366ASP C 431ASN C 452VAL C 478ASP C 519GLY C 558SER C 560ASN C 561PHE C 564ARG C 567ARG C 573ILE C 593 | THH C 643 |
3K8M_A_ACRA720 | 3k8m | ACR DB00284(Acarbose) | Bacteroidesthetaiotaomicron | ALPHA-AMYLASE, SUSG | PF00128(Alpha-amylase) | 7 | TYR A 260GLU A 263TRP A 287LEU A 290TRP A 299LYS A 304ASN A 330 | ACR A 720 |
3K8M_A_ACRA730 | 3k8m | ACR DB00284(Acarbose) | Bacteroidesthetaiotaomicron | ALPHA-AMYLASE, SUSG | PF00128(Alpha-amylase) | 5 | ARG A 457TRP A 460TYR A 469LYS A 472ASP A 473 | ACR A 730 |
3K8M_B_ACRB820 | 3k8m | ACR DB00284(Acarbose) | Bacteroidesthetaiotaomicron | ALPHA-AMYLASE, SUSG | no annotation | 7 | TYR B 260GLU B 263TRP B 287LEU B 290TRP B 299LYS B 304ASN B 330 | ACR B 820 |
3K8M_B_ACRB830 | 3k8m | ACR DB00284(Acarbose) | Bacteroidesthetaiotaomicron | ALPHA-AMYLASE, SUSG | no annotation | 5 | ARG B 457TRP B 460TYR B 469LYS B 472ASP B 473 | ACR B 830 |
3MBH_A_PXLA400 | 3mbh | PXL DB00147(Pyridoxal) | Bacteroidesthetaiotaomicron | PUTATIVEPHOSPHOMETHYLPYRIMIDINE KINASE | PF08543(Phos_pyr_kin) | 11 | ASP A 14SER A 16VAL A 21LEU A 45HIS A 48THR A 49GLN A 50TYR A 84VAL A 113TYR A 121ASP A 224 | PXL A 400 |
3MBH_B_PXLB400 | 3mbh | PXL DB00147(Pyridoxal) | Bacteroidesthetaiotaomicron | PUTATIVEPHOSPHOMETHYLPYRIMIDINE KINASE | no annotation | 12 | ASP B 14SER B 16VAL B 21SER B 22LEU B 45HIS B 48THR B 49GLN B 50TYR B 84VAL B 113TYR B 121ASP B 224 | PXL B 400 |
3MBH_C_PXLC400 | 3mbh | PXL DB00147(Pyridoxal) | Bacteroidesthetaiotaomicron | PUTATIVEPHOSPHOMETHYLPYRIMIDINE KINASE | no annotation | 12 | ASP C 14SER C 16VAL C 21SER C 22LEU C 45HIS C 48THR C 49GLN C 50TYR C 84VAL C 113TYR C 121ASP C 224 | PXL C 400 |
3MBH_D_PXLD400 | 3mbh | PXL DB00147(Pyridoxal) | Bacteroidesthetaiotaomicron | PUTATIVEPHOSPHOMETHYLPYRIMIDINE KINASE | no annotation | 12 | ASP D 14SER D 16VAL D 21SER D 22LEU D 45HIS D 48THR D 49GLN D 50TYR D 84VAL D 113TYR D 121ASP D 224 | PXL D 400 |
3MBH_E_PXLE400 | 3mbh | PXL DB00147(Pyridoxal) | Bacteroidesthetaiotaomicron | PUTATIVEPHOSPHOMETHYLPYRIMIDINE KINASE | no annotation | 12 | ASP E 14SER E 16VAL E 21SER E 22LEU E 45HIS E 48THR E 49GLN E 50TYR E 84VAL E 113TYR E 121ASP E 224 | PXL E 400 |
3MBH_F_PXLF400 | 3mbh | PXL DB00147(Pyridoxal) | Bacteroidesthetaiotaomicron | PUTATIVEPHOSPHOMETHYLPYRIMIDINE KINASE | no annotation | 11 | ASP F 14SER F 16VAL F 21LEU F 45HIS F 48THR F 49GLN F 50TYR F 84VAL F 113TYR F 121ASP F 224 | PXL F 400 |
3SXJ_A_SAMA258 | 3sxj | SAM DB00118(S-Adenosylmethionine) | Bacteroidesthetaiotaomicron | PUTATIVEMETHYLTRANSFERASE | PF13649(Methyltransf_25) | 13 | ARG A 25GLN A 26GLY A 54GLY A 56GLN A 60ASP A 76LEU A 77SER A 104MET A 105GLU A 121ALA A 123TYR A 125ASN A 126 | SAM A 258 |
3SXJ_B_SAMB258 | 3sxj | SAM DB00118(S-Adenosylmethionine) | Bacteroidesthetaiotaomicron | PUTATIVEMETHYLTRANSFERASE | None | 13 | ARG B 25GLN B 26GLY B 54GLY B 56GLN B 60ASP B 76LEU B 77SER B 104MET B 105GLU B 121ALA B 123TYR B 125ASN B 126 | SAM B 258 |
3V3N_A_MIYA2001 | 3v3n | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | PF01494(FAD_binding_3) | 11 | GLN A 192ARG A 213MET A 215PHE A 224HIS A 234GLY A 236SER A 238PRO A 318PHE A 319GLY A 321ASN A 371 | MIY A2001 |
3V3N_B_MIYB2001 | 3v3n | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 8 | GLN B 192ARG B 213PHE B 224HIS B 234GLY B 236GLY B 321ASN B 371MET B 375 | MIY B2001 |
3V3N_C_MIYC2001 | 3v3n | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 8 | GLN C 192ARG C 213PHE C 224HIS C 234GLY C 236GLY C 321ASN C 371MET C 375 | MIY C2001 |
3V3N_D_MIYD2001 | 3v3n | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 11 | GLN D 192ARG D 213MET D 215PHE D 224HIS D 234GLY D 236SER D 238PHE D 319GLY D 321ASN D 371MET D 375 | MIY D2001 |
3V3O_A_T1CA404 | 3v3o | T1C DB00560(Tigecycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | PF01494(FAD_binding_3) | 13 | THR A 59GLU A 114GLN A 192ARG A 213PHE A 224ASN A 226HIS A 234GLY A 236ALA A 320GLY A 321ASN A 371MET A 375GLN A 383 | T1C A 404 |
3V3O_B_T1CB405 | 3v3o | T1C DB00560(Tigecycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 12 | GLN B 192ARG B 213PHE B 224ASN B 226HIS B 234GLY B 236PRO B 318ALA B 320GLY B 321GLU B 367ASN B 371MET B 375 | T1C B 405 |
3V3O_C_T1CC401 | 3v3o | T1C DB00560(Tigecycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 11 | ASP C 61ASN C 190GLN C 192ARG C 213PHE C 224HIS C 234GLY C 236SER C 238PRO C 318GLY C 321MET C 375 | T1C C 401 |
3V3O_D_T1CD401 | 3v3o | T1C DB00560(Tigecycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 10 | ASP D 61HIS D 63GLN D 192ARG D 213MET D 215PHE D 224ASN D 226GLY D 236GLY D 321MET D 375 | T1C D 401 |
3WFA_A_EDTA802 | 3wfa | EDT DB00974(EdeticAcid) | Bacteroidesthetaiotaomicron | ALPHA-GLUCOSIDASE | NonePF10566(GH97_N)PF14508(GH97_C)PF14509(Glyco_hydro_97) | 5 | TYR B 407ARG B 449ASN A 488TYR A 492LYS A 495 | EDT A 802 |
3WFA_B_EDTB802 | 3wfa | EDT DB00974(EdeticAcid) | Bacteroidesthetaiotaomicron | ALPHA-GLUCOSIDASE | NonePF10566(GH97_N)PF14508(GH97_C)PF14509(Glyco_hydro_97) | 6 | ASP B 250TYR A 407ARG A 449ASN B 488TYR B 492LYS B 495 | EDT B 802 |
4A6N_A_T1CA392 | 4a6n | T1C DB00560(Tigecycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | PF01494(FAD_binding_3) | 11 | GLN A 192ARG A 213PHE A 224ASN A 226GLY A 236PRO A 318ALA A 320GLY A 321GLU A 367ASN A 371MET A 375 | T1C A 392 |
4A6N_B_T1CB392 | 4a6n | T1C DB00560(Tigecycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | PF01494(FAD_binding_3) | 11 | GLN B 192ARG B 213MET B 215PHE B 224ASN B 226HIS B 234GLY B 236PRO B 318GLY B 321GLU B 367MET B 375 | T1C B 392 |
4A6N_C_T1CC392 | 4a6n | T1C DB00560(Tigecycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 11 | ASN C 190GLN C 192ARG C 213MET C 215PHE C 224ASN C 226GLY C 236SER C 238PRO C 318GLY C 321MET C 375 | T1C C 392 |
4A6N_D_T1CD392 | 4a6n | T1C DB00560(Tigecycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 9 | GLN D 192ARG D 213PHE D 224ASN D 226HIS D 234GLY D 236SER D 238PRO D 318MET D 375 | T1C D 392 |
4A99_A_MIYA391 | 4a99 | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | PF01494(FAD_binding_3) | 10 | GLN A 192ARG A 213MET A 215PHE A 224ASN A 226HIS A 234GLY A 236SER A 238GLY A 321MET A 375 | MIY A 391 |
4A99_A_MIYA392 | 4a99 | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | PF01494(FAD_binding_3)no annotation | 9 | SER C 66LYS A 72LEU A 77GLN A 78TYR A 81PHE A 110GLN C 322SER C 326VAL C 329 | MIY A 392 |
4A99_B_MIYB391 | 4a99 | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 11 | GLN B 192ARG B 213MET B 215PHE B 224ASN B 226HIS B 234GLY B 236SER B 238PRO B 318GLY B 321MET B 375 | MIY B 391 |
4A99_C_MIYC391 | 4a99 | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 11 | ASN C 190GLN C 192ARG C 213MET C 215PHE C 224ASN C 226HIS C 234GLY C 236SER C 238GLY C 321MET C 375 | MIY C 391 |
4A99_C_MIYC392 | 4a99 | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | PF01494(FAD_binding_3)no annotation | 12 | LYS A 64TYR A 81PRO A 106GLU A 107ARG A 109PHE A 110VAL C 329ILE C 333GLN C 356ILE C 359TYR C 360GLU C 363 | MIY C 392 |
4A99_D_MIYD391 | 4a99 | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 11 | GLN D 192ARG D 213MET D 215PHE D 224ASN D 226HIS D 234GLY D 236SER D 238GLY D 321ASN D 371MET D 375 | MIY D 391 |
4A99_D_MIYD392 | 4a99 | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 5 | HIS D 63SER D 66GLN D 322SER D 326VAL D 329 | MIY D 392 |
4A99_D_MIYD393 | 4a99 | MIY DB01017(Minocycline) | Bacteroidesthetaiotaomicron | TETX2 PROTEIN | no annotation | 5 | ILE D 333GLN D 356ILE D 359TYR D 360GLU D 363 | MIY D 393 |
4D1Y_A_RBFA1176 | 4d1y | RBF DB00140(Riboflavin) | Bacteroidesthetaiotaomicron | PUTATIVE PROTEASE I | PF01965(DJ-1_PfpI)no annotation | 8 | GLN B 20GLN A 20LYS B 147ASN B 161ASN A 161THR B 162TRP B 164TRP A 164 | RBF A1176 |