DRUG BINDING INTERFACES MAPPED TO 'Bacillus anthracis'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
2QK8_A_MTXA200 | 2qk8 | MTX DB00563(Methotrexate) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE | PF00186(DHFR_1) | 16 | MET A 6ALA A 8LEU A 21GLU A 28LEU A 29VAL A 32LYS A 33ASN A 47ILE A 51ARG A 53LEU A 55PRO A 56ARG A 58PHE A 96TYR A 102THR A 115 | MTX A 200 |
3DAT_A_MTXA201 | 3dat | MTX DB00563(Methotrexate) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE | PF00186(DHFR_1) | 16 | MET A 6ALA A 8LEU A 21GLU A 28LEU A 29GLN A 30VAL A 32LYS A 33ASN A 47ILE A 51ARG A 53LEU A 55ARG A 58PHE A 96TYR A 102THR A 115 | MTX A 201 |
3FL9_A_TOPA200 | 3fl9 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE (DHFR) | PF00186(DHFR_1) | 10 | MET A 6ALA A 8LEU A 21GLU A 28VAL A 32ALA A 50ILE A 51LEU A 55PHE A 96TYR A 102 | TOP A 200 |
3FL9_B_TOPB200 | 3fl9 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE (DHFR) | no annotation | 12 | MET B 6ALA B 8ASN B 20LEU B 21GLU B 28LEU B 29VAL B 32ILE B 51LEU B 55PHE B 96TYR B 102THR B 115 | TOP B 200 |
3FL9_C_TOPC200 | 3fl9 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE (DHFR) | no annotation | 11 | MET C 6ALA C 8ASN C 20LEU C 21GLU C 28LEU C 29VAL C 32ILE C 51LEU C 55PHE C 96THR C 115 | TOP C 200 |
3FL9_D_TOPD200 | 3fl9 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE (DHFR) | no annotation | 9 | MET D 6ALA D 8LEU D 21GLU D 28VAL D 32ILE D 51LEU D 55PHE D 96TYR D 102 | TOP D 200 |
3FL9_E_TOPE200 | 3fl9 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE (DHFR) | no annotation | 10 | MET E 6ALA E 8LEU E 21GLU E 28LEU E 29VAL E 32ILE E 51LEU E 55PHE E 96THR E 115 | TOP E 200 |
3FL9_F_TOPF200 | 3fl9 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE (DHFR) | no annotation | 10 | MET F 6ALA F 8ASN F 20LEU F 21GLU F 28VAL F 32ALA F 50ILE F 51LEU F 55PHE F 96 | TOP F 200 |
3FL9_G_TOPG200 | 3fl9 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE (DHFR) | no annotation | 12 | MET G 6ALA G 8ASN G 20LEU G 21GLU G 28LEU G 29VAL G 32ILE G 51LEU G 55PHE G 96TYR G 102THR G 115 | TOP G 200 |
3FL9_H_TOPH200 | 3fl9 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE (DHFR) | no annotation | 9 | MET H 6ALA H 8GLU H 28LEU H 29VAL H 32ILE H 51LEU H 55PHE H 96THR H 115 | TOP H 200 |
3JW3_A_TOPA208 | 3jw3 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE | PF00186(DHFR_1) | 10 | MET A 6ALA A 8GLU A 28LEU A 29VAL A 32ILE A 51LEU A 55ILE A 96TYR A 102THR A 115 | TOP A 208 |
3JW3_B_TOPB208 | 3jw3 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE | no annotation | 9 | MET B 6ALA B 8LEU B 21GLU B 28VAL B 32ILE B 51LEU B 55ILE B 96TYR B 102 | TOP B 208 |
3JW5_A_TOPA208 | 3jw5 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE | PF00186(DHFR_1) | 11 | MET A 6ALA A 8ASN A 20LEU A 21GLU A 28LEU A 29VAL A 32ASN A 47ILE A 51PHE A 96THR A 115 | TOP A 208 |
3JW5_B_TOPB208 | 3jw5 | TOP DB00440(Trimethoprim) | Bacillusanthracis | DIHYDROFOLATEREDUCTASE | no annotation | 10 | MET B 6ALA B 8LEU B 21GLU B 28LEU B 29VAL B 32ILE B 51LEU B 55PHE B 96THR B 115 | TOP B 208 |
3TJ7_A_ACTA604 | 3tj7 | ACT DB03166(Aceticacid) | Bacillusanthracis | GBAA_1210 PROTEIN | NonePF01928(CYTH) | 6 | VAL B 34HIS B 36TYR A 115GLY A 117SER B 118THR B 120 | ACT A 604 |
3TJ7_A_ACTA609 | 3tj7 | ACT DB03166(Aceticacid) | Bacillusanthracis | GBAA_1210 PROTEIN | PF01928(CYTH) | 3 | LYS A 32VAL A 34HIS A 56 | ACT A 609 |
3TJ7_C_ACTC606 | 3tj7 | ACT DB03166(Aceticacid) | Bacillusanthracis | GBAA_1210 PROTEIN | None | 6 | VAL D 34HIS D 36TYR C 115GLY C 117SER D 118THR D 120 | ACT C 606 |
3TJ7_C_ACTC608 | 3tj7 | ACT DB03166(Aceticacid) | Bacillusanthracis | GBAA_1210 PROTEIN | None | 5 | GLU C 8ARG C 55LYS C 66ARG C 123GLU C 149 | ACT C 608 |
3TJ7_C_ACTC610 | 3tj7 | ACT DB03166(Aceticacid) | Bacillusanthracis | GBAA_1210 PROTEIN | None | 3 | ALA D 51ARG D 53ASN C 142 | ACT C 610 |
3TJ7_D_ACTD605 | 3tj7 | ACT DB03166(Aceticacid) | Bacillusanthracis | GBAA_1210 PROTEIN | None | 6 | VAL C 34HIS C 36TYR D 115GLY D 117SER C 118THR C 120 | ACT D 605 |
3TYE_B_YTZB902 | 3tye | YTZ DB06147(Sulfathiazole) | Bacillusanthracis | DIHYDROPTEROATESYNTHASE | no annotation | 3 | PHE B 189LYS B 220SER B 221 | YTZ B 902 |
4IR0_A_FCNA202 | 4ir0 | FCN DB00828(Fosfomycin) | Bacillusanthracis | METALLOTHIOLTRANSFERASE FOSB 2 | PF00903(Glyoxalase)no annotation | 11 | HIS B 7CYS B 9TRP B 46ALA B 48ASN B 50TYR A 64HIS A 66ARG A 94TYR A 105GLU A 115ARG A 124 | FCN A 202 |
4IR0_B_FCNB202 | 4ir0 | FCN DB00828(Fosfomycin) | Bacillusanthracis | METALLOTHIOLTRANSFERASE FOSB 2 | PF00903(Glyoxalase)no annotation | 11 | HIS A 7CYS A 9TRP A 46ALA A 48ASN A 50TYR B 64HIS B 66ARG B 94TYR B 105GLU B 115ARG B 124 | FCN B 202 |
4JD1_A_FCNA202 | 4jd1 | FCN DB00828(Fosfomycin) | Bacillusanthracis | METALLOTHIOLTRANSFERASE FOSB 2 | PF00903(Glyoxalase)no annotation | 12 | HIS B 7CYS B 9TYR B 39TRP B 46ALA B 48ASN B 50TYR A 64HIS A 66ARG A 94TYR A 105GLU A 115ARG A 124 | FCN A 202 |
4JD1_B_FCNB203 | 4jd1 | FCN DB00828(Fosfomycin) | Bacillusanthracis | METALLOTHIOLTRANSFERASE FOSB 2 | PF00903(Glyoxalase)no annotation | 12 | HIS A 7CYS A 9TYR A 39TRP A 46ALA A 48ASN A 50TYR B 64HIS B 66ARG B 94TYR B 105GLU B 115ARG B 124 | FCN B 203 |