DRUG BINDING INTERFACES MAPPED TO 'VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2'

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
3C7Q_A_XINA1172	3c7q	XIN DB09079 (Nintedanib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	12	LEU A 840 GLY A 841 GLU A 850 ALA A 866 LYS A 868 VAL A 899 VAL A 916 PHE A 918 CYS A 919 GLY A 922 LEU A1035 CYS A1045	XIN A1172
3WZD_A_LEVA1201	3wzd	LEV DB09078 (Lenvatinib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	17	LEU A 840 GLY A 841 VAL A 848 ALA A 866 LYS A 868 GLU A 885 ILE A 888 LEU A 889 VAL A 899 VAL A 916 CYS A 919 GLY A 922 LEU A1035 CYS A1045 ASP A1046 PHE A1047 LEU A1049	LEV A1201
3WZE_A_BAXA1201	3wze	BAX DB00398 (Sorafenib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	20	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 LEU A 889 ILE A 892 VAL A 898 VAL A 899 VAL A 916 PHE A 918 CYS A 919 GLY A 922 LEU A1019 HIS A1026 LEU A1035 ILE A1044 CYS A1045 ASP A1046 PHE A1047	BAX A1201
4AG8_A_AXIA2000	4ag8	AXI DB06626 (Axitinib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	14	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 VAL A 899 VAL A 914 VAL A 916 PHE A 918 CYS A 919 GLY A 922 LEU A1035 CYS A1045 PHE A1047	AXI A2000
4AGC_A_AXIA2000	4agc	AXI DB06626 (Axitinib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	14	ILE A 804 LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 LEU A 889 VAL A 899 VAL A 916 CYS A 919 GLY A 922 LEU A1035 CYS A1045 PHE A1047	AXI A2000
4AGD_A_B49A2000	4agd	B49 DB01268 (Sunitinib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	11	LEU A 840 ALA A 866 LYS A 868 VAL A 899 VAL A 916 PHE A 918 CYS A 919 GLY A 922 LEU A1035 CYS A1045 PHE A1047	B49 A2000
4ASD_A_BAXA1500	4asd	BAX DB00398 (Sorafenib)	Homo sapiens	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	PF07714 (Pkinase_Tyr)	18	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 LEU A 889 ILE A 892 VAL A 899 VAL A 916 PHE A 918 CYS A 919 GLY A 922 LEU A1019 HIS A1026 LEU A1035 ILE A1044 CYS A1045 PHE A1047	BAX A1500

[["3C7Q_A_XINA1172","3c7q","XIN","DB09079(Nintedanib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",12,"LEU A 840;GLY A 841;GLU A 850;ALA A 866;LYS A 868;VAL A 899;VAL A 916;PHE A 918;CYS A 919;GLY A 922;LEU A1035;CYS A1045","XIN A1172\r"],["3WZD_A_LEVA1201","3wzd","LEV","DB09078(Lenvatinib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",17,"LEU A 840;GLY A 841;VAL A 848;ALA A 866;LYS A 868;GLU A 885;ILE A 888;LEU A 889;VAL A 899;VAL A 916;CYS A 919;GLY A 922;LEU A1035;CYS A1045;ASP A1046;PHE A1047;LEU A1049","LEV A1201\r"],["3WZE_A_BAXA1201","3wze","BAX","DB00398(Sorafenib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",20,"LEU A 840;VAL A 848;ALA A 866;LYS A 868;GLU A 885;LEU A 889;ILE A 892;VAL A 898;VAL A 899;VAL A 916;PHE A 918;CYS A 919;GLY A 922;LEU A1019;HIS A1026;LEU A1035;ILE A1044;CYS A1045;ASP A1046;PHE A1047","BAX A1201\r"],["4AG8_A_AXIA2000","4ag8","AXI","DB06626(Axitinib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",14,"LEU A 840;VAL A 848;ALA A 866;LYS A 868;GLU A 885;VAL A 899;VAL A 914;VAL A 916;PHE A 918;CYS A 919;GLY A 922;LEU A1035;CYS A1045;PHE A1047","AXI A2000\r"],["4AGC_A_AXIA2000","4agc","AXI","DB06626(Axitinib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",14,"ILE A 804;LEU A 840;VAL A 848;ALA A 866;LYS A 868;GLU A 885;LEU A 889;VAL A 899;VAL A 916;CYS A 919;GLY A 922;LEU A1035;CYS A1045;PHE A1047","AXI A2000\r"],["4AGD_A_B49A2000","4agd","B49","DB01268(Sunitinib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",11,"LEU A 840;ALA A 866;LYS A 868;VAL A 899;VAL A 916;PHE A 918;CYS A 919;GLY A 922;LEU A1035;CYS A1045;PHE A1047","B49 A2000\r"],["4ASD_A_BAXA1500","4asd","BAX","DB00398(Sorafenib)","Homo sapiens","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","PF07714(Pkinase_Tyr)",18,"LEU A 840;VAL A 848;ALA A 866;LYS A 868;GLU A 885;LEU A 889;ILE A 892;VAL A 899;VAL A 916;PHE A 918;CYS A 919;GLY A 922;LEU A1019;HIS A1026;LEU A1035;ILE A1044;CYS A1045;PHE A1047","BAX A1500\r"]]