DRUG BINDING INTERFACES MAPPED TO 'TYROSINE-PROTEIN KINASE RECEPTOR'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
2IVU_A_ZD6A3015 | 2ivu | ZD6 DB05294(Vandetanib) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE RECEPTOR RETPRECURSOR | PF07714(Pkinase_Tyr) | 15 | LEU A 730GLY A 731VAL A 738ALA A 756LYS A 758GLU A 775LEU A 779LEU A 802VAL A 804TYR A 806ALA A 807GLY A 810LEU A 881SER A 891ASP A 892 | ZD6 A3015 |
2XP2_A_VGHA9000 | 2xp2 | VGH DB08865(Crizotinib) | Homo sapiens | TYROSINE-PROTEINKINASE RECEPTOR | PF07714(Pkinase_Tyr) | 9 | LEU A1122VAL A1130ALA A1148LEU A1196MET A1199GLY A1202LEU A1256GLY A1269ASP A1270 | VGH A9000 |
2YFX_A_VGHA9000 | 2yfx | VGH DB08865(Crizotinib) | Homo sapiens | TYROSINE-PROTEINKINASE RECEPTOR | PF07714(Pkinase_Tyr) | 8 | LEU A1122ALA A1148MET A1196MET A1199GLY A1202LEU A1256GLY A1269ASP A1270 | VGH A9000 |
4CKI_A_ADNA2022 | 4cki | ADN DB00640(Adenosine) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE RECEPTOR RET | PF07714(Pkinase_Tyr) | 11 | LEU A 730GLY A 731GLY A 733VAL A 738ALA A 756VAL A 804TYR A 806ALA A 807GLY A 810SER A 811LEU A 881 | ADN A2022 |
4CKJ_A_ADNA2014 | 4ckj | ADN DB00640(Adenosine) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE RECEPTOR RET | PF07714(Pkinase_Tyr) | 10 | LEU A 730GLY A 731GLY A 733VAL A 738ALA A 756VAL A 804TYR A 806ALA A 807SER A 811LEU A 881 | ADN A2014 |
6FEK_A_ADNA1104 | 6fek | ADN DB00640(Adenosine) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE RECEPTOR RET | no annotation | 11 | LEU A 730GLY A 731VAL A 738ALA A 756ILE A 788VAL A 804TYR A 806ALA A 807GLY A 810SER A 811LEU A 881 | ADN A1104 |