DRUG BINDING INTERFACES MAPPED TO 'TYROSINE-PROTEIN KINASE JAK2'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 3FUP_A_MI1A1 | 3fup | MI1 DB08895(Tofacitinib) | Homo sapiens | TYROSINE-PROTEINKINASE JAK2 | PF07714(Pkinase_Tyr) | 13 | LEU A 855GLY A 856GLY A 858GLY A 861VAL A 863ALA A 880LYS A 882MET A 929TYR A 931SER A 936ASN A 981LEU A 983ASP A 994 | MI1 A 1 |
| 3FUP_B_MI1B1 | 3fup | MI1 DB08895(Tofacitinib) | Homo sapiens | TYROSINE-PROTEINKINASE JAK2 | no annotation | 13 | LEU B 855GLY B 856GLY B 858VAL B 863ALA B 880LYS B 882VAL B 911MET B 929TYR B 931LEU B 932ASN B 981LEU B 983ASP B 994 | MI1 B 1 |
| 4FVQ_A_ACTA903 | 4fvq | ACT DB03166(Aceticacid) | Homo sapiens | TYROSINE-PROTEINKINASE JAK2 | PF07714(Pkinase_Tyr) | 4 | ASN A 673CYS A 675ARG A 715TRP A 718 | ACT A 903 |
| 4FVQ_A_ACTA904 | 4fvq | ACT DB03166(Aceticacid) | Homo sapiens | TYROSINE-PROTEINKINASE JAK2 | PF07714(Pkinase_Tyr) | 3 | PHE A 560VAL A 582GLU A 621 | ACT A 904 |