DRUG BINDING INTERFACES MAPPED TO 'TYROSINE-PROTEIN KINASE BTK'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 3K54_A_1N1A1 | 3k54 | 1N1 DB01254(Dasatinib) | Homo sapiens | TYROSINE-PROTEINKINASE BTK | PF07714(Pkinase_Tyr) | 13 | LEU A 408ALA A 428LYS A 430GLU A 445MET A 449VAL A 458ILE A 472THR A 474TYR A 476MET A 477GLY A 480LEU A 528SER A 538 | 1N1 A 1 |
| 3OCT_A_1N1A663 | 3oct | 1N1 DB01254(Dasatinib) | Homo sapiens | TYROSINE-PROTEINKINASE BTK | PF07714(Pkinase_Tyr) | 17 | LEU A 408PHE A 413VAL A 416ALA A 428LYS A 430MET A 449VAL A 458ILE A 472THR A 474TYR A 476MET A 477ASN A 479GLY A 480GLU A 488LEU A 528SER A 538PHE A 540 | 1N1 A 663 |
| 5P9I_A_1E8A701 | 5p9i | 1E8 DB09053(Ibrutinib) | Homo sapiens | TYROSINE-PROTEINKINASE BTK | PF07714(Pkinase_Tyr) | 17 | LEU A 408GLY A 411VAL A 416ALA A 428LYS A 430MET A 449ILE A 472THR A 474TYR A 476MET A 477GLY A 480CYS A 481ASN A 484LEU A 528SER A 538ASP A 539PHE A 540 | 1E8 A 701 |