DRUG BINDING INTERFACES MAPPED TO 'TUBULIN BETA-2B CHAIN'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
2WBE_B_TA1B1439 | 2wbe | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230SER B 236PHE B 272LEU B 275THR B 276ARG B 278PRO B 360ARG B 369GLY B 370 | TA1 B1439 |
3E22_B_LOCB700 | 3e22 | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1CCHAIN;TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | SER A 178ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259ALA B 316VAL B 318LYS B 352 | LOC B 700 |
3E22_D_LOCD700 | 3e22 | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1CCHAIN;TUBULIN BETA-2BCHAIN | no annotation | 14 | SER C 178ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248ALA D 250LYS D 254LEU D 255ASN D 258MET D 259ALA D 316VAL D 318LYS D 352 | LOC D 700 |
4O2B_B_LOCB503 | 4o2b | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 16 | SER A 178ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 503 |
4O2B_D_LOCD503 | 4o2b | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | no annotation | 17 | SER C 178ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248ALA D 250LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316ILE D 318LYS D 352ALA D 354ILE D 378 | LOC D 503 |
5HNW_B_TA1B902 | 5hnw | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 13 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230SER B 236PHE B 272LEU B 275THR B 276ARG B 278PRO B 360ARG B 369 | TA1 B 902 |
5HNX_B_TA1B902 | 5hnx | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 12 | VAL B 23ASP B 26GLU B 27HIS B 229LEU B 230SER B 236PHE B 272LEU B 275THR B 276ARG B 278PRO B 360ARG B 369 | TA1 B 902 |
5HNY_B_TA1B601 | 5hny | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 13 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230SER B 236PHE B 272LEU B 275THR B 276ARG B 278PRO B 360ARG B 369 | TA1 B 601 |
5HNZ_B_TA1B902 | 5hnz | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | VAL B 23ASP B 26GLU B 27LEU B 217ASP B 226HIS B 229LEU B 230ALA B 233SER B 236PHE B 272LEU B 275THR B 276ARG B 278PRO B 360ARG B 369 | TA1 B 902 |
5ITZ_B_LOCB502 | 5itz | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 502 |
5J2T_C_VLBC503 | 5j2t | VLB DB00570(Vinblastine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C)no annotation | 21 | LYS B 176VAL B 177ASP B 179TYR B 210PHE B 214THR B 221PRO B 222TYR B 224LEU B 227LEU C 248PRO C 325LYS C 326VAL C 328ASN C 329ILE C 332ALA C 333LYS C 336PHE C 351VAL C 353GLY C 354ILE C 355 | VLB C 503 |
5JH7_B_6K9B503 | 5jh7 | 6K9 DB08871(Eribulin) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | NonePF00091(Tubulin)PF03953(Tubulin_C) | 18 | GLN B 11ASN B 101VAL B 177SER B 178ASP B 179THR B 180GLU B 183TYR B 210PRO B 222TYR B 224LEU B 227LEU C 248VAL C 250GLU C 254ASN C 329ILE C 332LYS C 352VAL C 353 | 6K9 B 503 |
5JH7_D_6K9D502 | 5jh7 | 6K9 DB08871(Eribulin) | Bos taurus | TUBULIN BETA-2BCHAIN | None | 11 | GLN D 11ASN D 101VAL D 177SER D 178ASP D 179THR D 180GLU D 183TYR D 210PRO D 222TYR D 224LEU D 227 | 6K9 D 502 |
5M50_B_TA1B502 | 5m50 | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 12 | VAL B 23ASP B 26GLU B 27HIS B 229SER B 236THR B 276GLN B 281ARG B 320PRO B 360ARG B 369GLY B 370LEU B 371 | TA1 B 502 |
5M50_E_TA1E502 | 5m50 | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | no annotation | 13 | VAL E 23ASP E 26GLU E 27LEU E 217HIS E 229SER E 236THR E 276GLN E 281ARG E 320PRO E 360ARG E 369GLY E 370LEU E 371 | TA1 E 502 |
5M54_B_TA1B502 | 5m54 | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 13 | VAL B 23ASP B 26GLU B 27HIS B 229LEU B 230ALA B 233SER B 236PHE B 272THR B 276ARG B 278GLN B 281ARG B 369LEU B 371 | TA1 B 502 |
5M54_E_TA1E502 | 5m54 | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | no annotation | 14 | VAL E 23ASP E 26GLU E 27HIS E 229LEU E 230ALA E 233SER E 236PHE E 272THR E 276ARG E 278GLN E 281ARG E 369GLY E 370LEU E 371 | TA1 E 502 |
5M5C_B_TA1B502 | 5m5c | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 12 | VAL B 23ASP B 26GLU B 27HIS B 229LEU B 230ALA B 233SER B 236THR B 276GLN B 281ARG B 369GLY B 370LEU B 371 | TA1 B 502 |
5M5C_E_TA1E502 | 5m5c | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | no annotation | 10 | VAL E 23ASP E 26GLU E 27HIS E 229LEU E 230ALA E 233SER E 236THR E 276GLY E 370LEU E 371 | TA1 E 502 |
5ND2_B_TA1B601 | 5nd2 | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230ALA B 233SER B 236PHE B 272THR B 276ARG B 278ARG B 320PRO B 360LEU B 371 | TA1 B 601 |
5ND3_B_TA1B601 | 5nd3 | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 13 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230ALA B 233SER B 236THR B 276ARG B 278ARG B 320PRO B 360ARG B 369 | TA1 B 601 |
5ND4_B_TA1B601 | 5nd4 | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | VAL B 23ASP B 26GLU B 27ASP B 226HIS B 229LEU B 230ALA B 233SER B 236PHE B 272THR B 276ARG B 278ARG B 320PRO B 360LEU B 371 | TA1 B 601 |
5ND7_B_TA1B601 | 5nd7 | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230ALA B 233SER B 236PHE B 272THR B 276ARG B 278ARG B 320PRO B 360ARG B 369LEU B 371 | TA1 B 601 |
5NM5_B_LOCB502 | 5nm5 | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 18 | ASN A 101SER A 178ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ALA B 354ILE B 378 | LOC B 502 |