DRUG BINDING INTERFACES MAPPED TO 'TUBULIN BETA CHAIN'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1IA0_B_TXLB502 | 1ia0 | TXL DB01248(Docetaxel) | Sus scrofa | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | VAL B 23ASP B 26LEU B 217ASP B 226HIS B 229SER B 236PHE B 272THR B 276ARG B 278ARG B 320PRO B 360ARG B 369GLY B 370LEU B 371 | TXL B 502 |
1JFF_B_TA1B601 | 1jff | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230SER B 236PHE B 272LEU B 275THR B 276ARG B 278PRO B 360ARG B 369GLY B 370 | TA1 B 601 |
1SA1_B_PODB700 | 1sa1 | POD DB01179(Podofilox) | Bos taurus | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 12 | VAL A 181CYS B 241LEU B 242ALA B 250LYS B 254LEU B 255ASN B 258MET B 259ALA B 316VAL B 318LYS B 352ALA B 354 | POD B 700 |
1SA1_D_PODD701 | 1sa1 | POD DB01179(Podofilox) | Bos taurus | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 12 | VAL C 181CYS D 241LEU D 242ALA D 250LYS D 254LEU D 255ASN D 258MET D 259ALA D 316VAL D 318LYS D 352ALA D 354 | POD D 701 |
1Z2B_C_VLBC800 | 1z2b | VLB DB00570(Vinblastine) | Bos taurus | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C)no annotation | 13 | LYS B 176VAL B 177ASP B 179TYR B 210THR B 221PRO B 222TYR B 224LEU B 227PRO C 325VAL C 328ASN C 329VAL C 353ILE C 355 | VLB C 800 |
2HXF_B_TA1B601 | 2hxf | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230SER B 236PHE B 272LEU B 275THR B 276ARG B 278PRO B 360ARG B 369GLY B 370 | TA1 B 601 |
2HXH_B_TA1B601 | 2hxh | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230SER B 236PHE B 272LEU B 275THR B 276ARG B 278PRO B 360ARG B 369GLY B 370 | TA1 B 601 |
2P4N_B_TA1B601 | 2p4n | TA1 DB01229(Paclitaxel) | Bos taurus | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230SER B 236PHE B 272LEU B 275THR B 276ARG B 278PRO B 360ARG B 369GLY B 370 | TA1 B 601 |
3J6G_B_TA1B502 | 3j6g | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 10 | VAL B 23ASP B 26HIS B 229LEU B 230SER B 236PHE B 272THR B 276GLN B 281ARG B 369LEU B 371 | TA1 B 502 |
3J6G_D_TA1D502 | 3j6g | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 10 | VAL D 23ASP D 26HIS D 229LEU D 230SER D 236PHE D 272THR D 276GLN D 281ARG D 369LEU D 371 | TA1 D 502 |
3J6G_F_TA1F502 | 3j6g | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 10 | VAL F 23ASP F 26HIS F 229LEU F 230SER F 236PHE F 272THR F 276GLN F 281ARG F 369LEU F 371 | TA1 F 502 |
3J6G_H_TA1H502 | 3j6g | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 10 | VAL H 23ASP H 26HIS H 229LEU H 230SER H 236PHE H 272THR H 276GLN H 281ARG H 369LEU H 371 | TA1 H 502 |
3J6G_J_TA1J502 | 3j6g | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 10 | VAL J 23ASP J 26HIS J 229LEU J 230SER J 236PHE J 272THR J 276GLN J 281ARG J 369LEU J 371 | TA1 J 502 |
3J6G_L_TA1L502 | 3j6g | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 10 | VAL L 23ASP L 26HIS L 229LEU L 230SER L 236PHE L 272THR L 276GLN L 281ARG L 369LEU L 371 | TA1 L 502 |
3J6G_N_TA1N502 | 3j6g | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 10 | VAL N 23ASP N 26HIS N 229LEU N 230SER N 236PHE N 272THR N 276GLN N 281ARG N 369LEU N 371 | TA1 N 502 |
3J6G_P_TA1P502 | 3j6g | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 10 | VAL P 23ASP P 26HIS P 229LEU P 230SER P 236PHE P 272THR P 276GLN P 281ARG P 369LEU P 371 | TA1 P 502 |
3J6G_R_TA1R502 | 3j6g | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 10 | VAL R 23ASP R 26HIS R 229LEU R 230SER R 236PHE R 272THR R 276GLN R 281ARG R 369LEU R 371 | TA1 R 502 |
3J6P_B_TA1B502 | 3j6p | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 13 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230SER B 236PHE B 272THR B 276ARG B 278PRO B 360GLY B 370LEU B 371 | TA1 B 502 |
3UT5_B_LOCB502 | 3ut5 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | ALA A 180VAL A 181CYS B 241LEU B 242ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 502 |
3UT5_D_LOCD502 | 3ut5 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 14 | ALA C 180VAL C 181CYS D 241LEU D 242GLN D 247ALA D 250LYS D 254LEU D 255ASN D 258MET D 259ALA D 316LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4EB6_C_VLBC503 | 4eb6 | VLB DB00570(Vinblastine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C)no annotation | 12 | VAL B 177ASP B 179TYR B 210THR B 221PRO B 222TYR B 224PRO C 325ASN C 329ILE C 332LYS C 336VAL C 353ILE C 355 | VLB C 503 |
4X1I_B_LOCB502 | 4x1i | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | SER A 178ALA A 180VAL A 181CYS B 241LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316VAL B 318LYS B 352ALA B 354 | LOC B 502 |
4X1I_D_LOCD502 | 4x1i | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 14 | ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4X1K_B_LOCB502 | 4x1k | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 12 | SER A 178VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258THR B 314LYS B 352ALA B 354 | LOC B 502 |
4X1K_D_LOCD502 | 4x1k | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 17 | ASN C 101SER C 178ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316VAL D 318LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4X1Y_B_LOCB502 | 4x1y | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316VAL B 318LYS B 352ILE B 378 | LOC B 502 |
4X1Y_D_LOCD502 | 4x1y | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 16 | SER C 178ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316VAL D 318LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4X20_B_LOCB502 | 4x20 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 16 | SER A 178VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316VAL B 318LYS B 352ALA B 354ILE B 378 | LOC B 502 |
4X20_D_LOCD502 | 4x20 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 14 | SER C 178ALA C 180VAL C 181LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316VAL D 318LYS D 352ILE D 378 | LOC D 502 |
5BMV_C_VLBC507 | 5bmv | VLB DB00570(Vinblastine) | Bos taurus;Sus scrofa | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C)no annotation | 13 | LYS B 176ASP B 179TYR B 210PRO B 222TYR B 224LEU B 227PRO C 325VAL C 328ASN C 329ILE C 332PHE C 351VAL C 353ILE C 355 | VLB C 507 |
5EYP_B_LOCB502 | 5eyp | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 17 | SER A 178ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ALA B 354ILE B 378 | LOC B 502 |
5MIO_B_LOCB502 | 5mio | LOC DB01394(Colchicine) | Bos taurus;Ovis aries | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 502 |
5MM4_B_TA1B501 | 5mm4 | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 10 | VAL B 23GLU B 27LEU B 219HIS B 229ALA B 233SER B 236PHE B 272THR B 276PRO B 360LEU B 371 | TA1 B 501 |
5OGC_B_TA1B601 | 5ogc | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 14 | VAL B 23ASP B 26GLU B 27LEU B 217HIS B 229LEU B 230SER B 236PHE B 272THR B 276ARG B 278PRO B 360ARG B 369GLY B 370LEU B 371 | TA1 B 601 |
5SYE_B_TA1B502 | 5sye | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | GLU B 22VAL B 23ASP B 26LEU B 217ASP B 226HIS B 229ALA B 233SER B 236ARG B 278GLN B 281ARG B 320PRO B 360ARG B 369GLY B 370 | TA1 B 502 |
5SYF_B_TA1B502 | 5syf | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 12 | VAL B 23ASP B 26LEU B 217ASP B 226HIS B 229ALA B 233SER B 236ARG B 278GLN B 281PRO B 360ARG B 369LEU B 371 | TA1 B 502 |
5W3J_B_TA1B502 | 5w3j | TA1 DB01229(Paclitaxel) | Saccharomycescerevisiae | TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 8 | VAL B 23ASP B 26GLU B 27HIS B 227PRO B 358GLN B 359GLY B 360LEU B 361 | TA1 B 502 |
5XIW_B_LOCB504 | 5xiw | LOC DB01394(Colchicine) | Sus scrofa | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA CHAIN | no annotation | 17 | SER A 178ALA A 180VAL A 181CYS B 239LEU B 240LEU B 246ALA B 248LYS B 252LEU B 253ASN B 256MET B 257THR B 312ALA B 314ILE B 316LYS B 350ALA B 352ILE B 368 | LOC B 504 |
5XIW_D_LOCD503 | 5xiw | LOC DB01394(Colchicine) | Sus scrofa | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA CHAIN | no annotation | 17 | SER C 178ALA C 180VAL C 181CYS D 239LEU D 240LEU D 246ALA D 248LYS D 252LEU D 253ASN D 256MET D 257THR D 312ALA D 314ILE D 316LYS D 350ALA D 352ILE D 368 | LOC D 503 |
6B0C_D_TA1D502 | 6b0c | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 14 | VAL D 23GLU D 27LEU D 215ASP D 224HIS D 227LEU D 228ALA D 231SER D 234LEU D 273THR D 274ARG D 276PRO D 358GLY D 360LEU D 361 | TA1 D 502 |
6B0I_B_TA1B502 | 6b0i | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 13 | VAL B 23ASP B 26LEU B 215ASP B 224HIS B 227LEU B 228ALA B 231SER B 234ARG B 276PRO B 358ARG B 359GLY B 360LEU B 361 | TA1 B 502 |
6B0L_B_TA1B502 | 6b0l | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 13 | VAL B 23ASP B 26LEU B 215ASP B 224HIS B 227LEU B 228SER B 234THR B 274ARG B 276PRO B 358ARG B 359GLY B 360LEU B 361 | TA1 B 502 |
6EW0_B_TA1B501 | 6ew0 | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 17 | VAL B 23ASP B 26GLU B 27LEU B 215LEU B 217HIS B 227LEU B 228ALA B 231SER B 234LEU B 273THR B 274ARG B 276GLN B 279ARG B 318PRO B 358ARG B 359LEU B 361 | TA1 B 501 |
6EW0_D_TA1D501 | 6ew0 | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 17 | VAL D 23ASP D 26GLU D 27LEU D 215LEU D 217HIS D 227LEU D 228ALA D 231SER D 234LEU D 273THR D 274ARG D 276GLN D 279ARG D 318PRO D 358ARG D 359LEU D 361 | TA1 D 501 |
6EW0_F_TA1F502 | 6ew0 | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 17 | VAL F 23ASP F 26GLU F 27LEU F 215LEU F 217ASP F 224HIS F 227LEU F 228ALA F 231SER F 234LEU F 273THR F 274ARG F 276GLN F 279PRO F 358ARG F 359LEU F 361 | TA1 F 502 |
6EW0_G_TA1G501 | 6ew0 | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 18 | VAL G 23ASP G 26GLU G 27LEU G 215LEU G 217HIS G 227LEU G 228ALA G 231SER G 234PHE G 270LEU G 273THR G 274ARG G 276GLN G 279ARG G 318PRO G 358ARG G 359LEU G 361 | TA1 G 501 |
6EW0_H_TA1H501 | 6ew0 | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 17 | VAL H 23ASP H 26GLU H 27LEU H 215LEU H 217HIS H 227LEU H 228ALA H 231SER H 234LEU H 273THR H 274ARG H 276GLN H 279ARG H 318PRO H 358ARG H 359LEU H 361 | TA1 H 501 |
6EW0_I_TA1I501 | 6ew0 | TA1 DB01229(Paclitaxel) | Sus scrofa | TUBULIN BETA CHAIN | no annotation | 17 | VAL I 23ASP I 26GLU I 27LEU I 215LEU I 217HIS I 227LEU I 228ALA I 231SER I 234LEU I 273THR I 274ARG I 276GLN I 279ARG I 318PRO I 358ARG I 359LEU I 361 | TA1 I 501 |