DRUG BINDING INTERFACES MAPPED TO 'TUBULIN ALPHA-1B CHAIN'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
4O2B_B_LOCB503 | 4o2b | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 16 | SER A 178ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 503 |
4O2B_D_LOCD503 | 4o2b | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | no annotation | 17 | SER C 178ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248ALA D 250LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316ILE D 318LYS D 352ALA D 354ILE D 378 | LOC D 503 |
5BMV_C_VLBC507 | 5bmv | VLB DB00570(Vinblastine) | Bos taurus;Sus scrofa | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C)no annotation | 13 | LYS B 176ASP B 179TYR B 210PRO B 222TYR B 224LEU B 227PRO C 325VAL C 328ASN C 329ILE C 332PHE C 351VAL C 353ILE C 355 | VLB C 507 |
5ITZ_B_LOCB502 | 5itz | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 502 |
5J2T_C_VLBC503 | 5j2t | VLB DB00570(Vinblastine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C)no annotation | 21 | LYS B 176VAL B 177ASP B 179TYR B 210PHE B 214THR B 221PRO B 222TYR B 224LEU B 227LEU C 248PRO C 325LYS C 326VAL C 328ASN C 329ILE C 332ALA C 333LYS C 336PHE C 351VAL C 353GLY C 354ILE C 355 | VLB C 503 |
5JH7_B_6K9B503 | 5jh7 | 6K9 DB08871(Eribulin) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | NonePF00091(Tubulin)PF03953(Tubulin_C) | 18 | GLN B 11ASN B 101VAL B 177SER B 178ASP B 179THR B 180GLU B 183TYR B 210PRO B 222TYR B 224LEU B 227LEU C 248VAL C 250GLU C 254ASN C 329ILE C 332LYS C 352VAL C 353 | 6K9 B 503 |
5MIO_B_LOCB502 | 5mio | LOC DB01394(Colchicine) | Bos taurus;Ovis aries | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 502 |
5NM5_B_LOCB502 | 5nm5 | LOC DB01394(Colchicine) | Bos taurus | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA-2BCHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 18 | ASN A 101SER A 178ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ALA B 354ILE B 378 | LOC B 502 |
5XIW_B_LOCB504 | 5xiw | LOC DB01394(Colchicine) | Sus scrofa | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA CHAIN | no annotation | 17 | SER A 178ALA A 180VAL A 181CYS B 239LEU B 240LEU B 246ALA B 248LYS B 252LEU B 253ASN B 256MET B 257THR B 312ALA B 314ILE B 316LYS B 350ALA B 352ILE B 368 | LOC B 504 |
5XIW_D_LOCD503 | 5xiw | LOC DB01394(Colchicine) | Sus scrofa | TUBULIN ALPHA-1BCHAIN;TUBULIN BETA CHAIN | no annotation | 17 | SER C 178ALA C 180VAL C 181CYS D 239LEU D 240LEU D 246ALA D 248LYS D 252LEU D 253ASN D 256MET D 257THR D 312ALA D 314ILE D 316LYS D 350ALA D 352ILE D 368 | LOC D 503 |