DRUG BINDING INTERFACES MAPPED TO 'TUBULIN ALPHA CHAIN'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1SA1_B_PODB700 | 1sa1 | POD DB01179(Podofilox) | Bos taurus | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 12 | VAL A 181CYS B 241LEU B 242ALA B 250LYS B 254LEU B 255ASN B 258MET B 259ALA B 316VAL B 318LYS B 352ALA B 354 | POD B 700 |
1SA1_D_PODD701 | 1sa1 | POD DB01179(Podofilox) | Bos taurus | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 12 | VAL C 181CYS D 241LEU D 242ALA D 250LYS D 254LEU D 255ASN D 258MET D 259ALA D 316VAL D 318LYS D 352ALA D 354 | POD D 701 |
1Z2B_C_VLBC800 | 1z2b | VLB DB00570(Vinblastine) | Bos taurus | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C)no annotation | 13 | LYS B 176VAL B 177ASP B 179TYR B 210THR B 221PRO B 222TYR B 224LEU B 227PRO C 325VAL C 328ASN C 329VAL C 353ILE C 355 | VLB C 800 |
3UT5_B_LOCB502 | 3ut5 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 14 | ALA A 180VAL A 181CYS B 241LEU B 242ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ILE B 378 | LOC B 502 |
3UT5_D_LOCD502 | 3ut5 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 14 | ALA C 180VAL C 181CYS D 241LEU D 242GLN D 247ALA D 250LYS D 254LEU D 255ASN D 258MET D 259ALA D 316LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4EB6_C_VLBC503 | 4eb6 | VLB DB00570(Vinblastine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C)no annotation | 12 | VAL B 177ASP B 179TYR B 210THR B 221PRO B 222TYR B 224PRO C 325ASN C 329ILE C 332LYS C 336VAL C 353ILE C 355 | VLB C 503 |
4X1I_B_LOCB502 | 4x1i | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | SER A 178ALA A 180VAL A 181CYS B 241LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316VAL B 318LYS B 352ALA B 354 | LOC B 502 |
4X1I_D_LOCD502 | 4x1i | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 14 | ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4X1K_B_LOCB502 | 4x1k | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 12 | SER A 178VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258THR B 314LYS B 352ALA B 354 | LOC B 502 |
4X1K_D_LOCD502 | 4x1k | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 17 | ASN C 101SER C 178ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316VAL D 318LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4X1Y_B_LOCB502 | 4x1y | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 15 | ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316VAL B 318LYS B 352ILE B 378 | LOC B 502 |
4X1Y_D_LOCD502 | 4x1y | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 16 | SER C 178ALA C 180VAL C 181CYS D 241LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316VAL D 318LYS D 352ALA D 354ILE D 378 | LOC D 502 |
4X20_B_LOCB502 | 4x20 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 16 | SER A 178VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316VAL B 318LYS B 352ALA B 354ILE B 378 | LOC B 502 |
4X20_D_LOCD502 | 4x20 | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | no annotation | 14 | SER C 178ALA C 180VAL C 181LEU D 242LEU D 248LYS D 254LEU D 255ASN D 258MET D 259THR D 314ALA D 316VAL D 318LYS D 352ILE D 378 | LOC D 502 |
5EYP_B_LOCB502 | 5eyp | LOC DB01394(Colchicine) | Ovis aries | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN | PF00091(Tubulin)PF03953(Tubulin_C) | 17 | SER A 178ALA A 180VAL A 181CYS B 241LEU B 242LEU B 248ALA B 250LYS B 254LEU B 255ASN B 258MET B 259THR B 314ALA B 316ILE B 318LYS B 352ALA B 354ILE B 378 | LOC B 502 |