DRUG BINDING INTERFACES MAPPED TO 'STEROL 14-ALPHA-DEMETHYLASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 2WUZ_A_TPFA1460 | 2wuz | TPF DB00196(Fluconazole) | Trypanosoma cruzi | LANOSTEROL14-ALPHA-DEMETHYLASE, PUTATIVE | PF00067(p450) | 10 | TYR A 103MET A 106PHE A 110TYR A 116ALA A 287ALA A 291THR A 295LEU A 356MET A 460VAL A 461 | TPF A1460 |
| 2WUZ_B_TPFB1460 | 2wuz | TPF DB00196(Fluconazole) | Trypanosoma cruzi | LANOSTEROL14-ALPHA-DEMETHYLASE, PUTATIVE | no annotation | 10 | TYR B 103MET B 106PHE B 110TYR B 116ALA B 287ALA B 291THR B 295LEU B 356MET B 460VAL B 461 | TPF B1460 |
| 2WV2_A_TPFA1 | 2wv2 | TPF DB00196(Fluconazole) | Trypanosomabrucei | LANOSTEROL14-ALPHA-DEMETHYLASE | PF00067(p450) | 9 | TYR A 103MET A 106PHE A 110TYR A 116ALA A 287ALA A 291THR A 295LEU A 356MET A 460 | TPF A 1 |
| 2WX2_A_TPFA1460 | 2wx2 | TPF DB00196(Fluconazole) | Trypanosoma cruzi | LANOSTEROL14-ALPHA-DEMETHYLASE | PF00067(p450) | 7 | MET A 106PHE A 110TYR A 116ALA A 287ALA A 291THR A 295LEU A 356 | TPF A1460 |
| 2WX2_B_TPFB1460 | 2wx2 | TPF DB00196(Fluconazole) | Trypanosoma cruzi | LANOSTEROL14-ALPHA-DEMETHYLASE | no annotation | 8 | TYR B 103MET B 106PHE B 110TYR B 116ALA B 287ALA B 291THR B 295LEU B 356 | TPF B1460 |
| 2X2N_A_X2NA1480 | 2x2n | X2N DB01263(Posaconazole) | Trypanosomabrucei | LANOSTEROL14-ALPHA-DEMETHYLASE | PF00067(p450) | 14 | TYR A 103PHE A 105MET A 106PHE A 110TYR A 116ILE A 209PRO A 210ALA A 211ALA A 287ALA A 291THR A 295LEU A 356MET A 360MET A 460 | X2N A1480 |
| 2X2N_B_X2NB1479 | 2x2n | X2N DB01263(Posaconazole) | Trypanosomabrucei | LANOSTEROL14-ALPHA-DEMETHYLASE | no annotation | 13 | TYR B 103PHE B 105MET B 106PHE B 110TYR B 116PRO B 210ALA B 211ALA B 287ALA B 291THR B 295LEU B 356MET B 360MET B 460 | X2N B1479 |
| 2X2N_C_X2NC1479 | 2x2n | X2N DB01263(Posaconazole) | Trypanosomabrucei | LANOSTEROL14-ALPHA-DEMETHYLASE | no annotation | 13 | TYR C 103PHE C 105MET C 106PHE C 110TYR C 116PRO C 210VAL C 213ALA C 287ALA C 291THR C 295LEU C 356MET C 360MET C 460 | X2N C1479 |
| 2X2N_D_X2ND1479 | 2x2n | X2N DB01263(Posaconazole) | Trypanosomabrucei | LANOSTEROL14-ALPHA-DEMETHYLASE | no annotation | 13 | ILE D 46TYR D 103PHE D 105MET D 106PHE D 110TYR D 116PRO D 210ALA D 287ALA D 291THR D 295LEU D 356MET D 360MET D 460 | X2N D1479 |