DRUG BINDING INTERFACES MAPPED TO 'SERINE/THREONINE-PROTEIN KINASE PIM-1'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1YI4_A_ADNA306 | 1yi4 | ADN DB00640(Adenosine) | Homo sapiens | PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE PIM-1 | PF00069(Pkinase) | 10 | LEU A 44PHE A 49ALA A 65ILE A 104LEU A 120ARG A 122PRO A 123ASP A 128LEU A 174ILE A 185 | ADN A 306 |
4I41_A_MIXA500 | 4i41 | MIX DB01204(Mitoxantrone) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE PIM-1 | PF00069(Pkinase) | 16 | LEU A 44PHE A 49VAL A 52ALA A 65ILE A 104LEU A 120GLN A 127ASP A 128ASP A 131ASP A 167LYS A 169GLU A 171ASN A 172LEU A 174ILE A 185ASP A 186 | MIX A 500 |
4I41_A_MIXA501 | 4i41 | MIX DB01204(Mitoxantrone) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE PIM-1 | PF00069(Pkinase) | 12 | ILE A 133THR A 134LYS A 169ASP A 170THR A 204VAL A 206ASP A 234ASP A 239ILE A 240GLU A 243GLU A 247ARG A 256 | MIX A 501 |
4IAA_A_RTZA401 | 4iaa | RTZ DB00679(Thioridazine) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE PIM-1 | PF00069(Pkinase) | 11 | PHE A 49VAL A 52ALA A 65LYS A 67LEU A 120VAL A 126ASP A 128GLU A 171LEU A 174ILE A 185ASP A 186 | RTZ A 401 |