DRUG BINDING INTERFACES MAPPED TO 'SAM-DEPENDENT METHYLTRANSFERASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
3KU1_A_SAMA226 | 3ku1 | SAM DB00118(S-Adenosylmethionine) | Streptococcuspneumoniae | SAM-DEPENDENTMETHYLTRANSFERASE | NonePF04816(TrmK) | 14 | ARG A 5LEU A 6GLY A 23ARG B 36GLU A 46VAL A 47PRO A 51ASN A 74GLY A 75ALA A 91GLY A 92MET A 93LEU A 97ILE A 101 | SAM A 226 |
3KU1_C_SAMC226 | 3ku1 | SAM DB00118(S-Adenosylmethionine) | Streptococcuspneumoniae | SAM-DEPENDENTMETHYLTRANSFERASE | None | 14 | ARG C 5LEU C 6GLY C 23ASP C 25ARG D 36GLU C 46VAL C 47PRO C 51GLY C 75ALA C 91GLY C 92MET C 93LEU C 97ILE C 101 | SAM C 226 |
3KU1_G_SAMG226 | 3ku1 | SAM DB00118(S-Adenosylmethionine) | Streptococcuspneumoniae | SAM-DEPENDENTMETHYLTRANSFERASE | None | 13 | ARG G 5LEU G 6GLY G 23ASP G 25GLU G 46VAL G 47PRO G 51ASN G 74GLY G 75ALA G 91GLY G 92LEU G 97ILE G 101 | SAM G 226 |
3KU1_H_SAMH226 | 3ku1 | SAM DB00118(S-Adenosylmethionine) | Streptococcuspneumoniae | SAM-DEPENDENTMETHYLTRANSFERASE | None | 13 | ARG H 5LEU H 6GLY H 23ASP H 25GLU H 46VAL H 47VAL H 48PRO H 51GLY H 75ALA H 91MET H 93LEU H 97ILE H 101 | SAM H 226 |
3MB5_A_SAMA301 | 3mb5 | SAM DB00118(S-Adenosylmethionine) | Pyrococcus abyssi | SAM-DEPENDENTMETHYLTRANSFERASE | PF08704(GCD14)PF14801(GCD14_N) | 16 | ILE A 76VAL A 77GLY A 101GLY A 103SER A 104ALA A 106LEU A 107GLU A 125ILE A 126ARG A 127ASP A 153ILE A 154TYR A 155ASP A 169LEU A 170PRO A 171 | SAM A 301 |
3OU6_A_SAMA300 | 3ou6 | SAM DB00118(S-Adenosylmethionine) | Streptomycesluridus | SAM-DEPENDENTMETHYLTRANSFERASE | PF13649(Methyltransf_25) | 14 | LEU A 12TYR A 15TYR A 22ALA A 54GLY A 56TRP A 60ASP A 75GLY A 76SER A 77MET A 80ASP A 98LEU A 99ALA A 114TRP A 116 | SAM A 300 |
3OU6_B_SAMB300 | 3ou6 | SAM DB00118(S-Adenosylmethionine) | Streptomycesluridus | SAM-DEPENDENTMETHYLTRANSFERASE | None | 15 | LEU B 12TYR B 15TYR B 22ALA B 54GLY B 56TRP B 60ASP B 75GLY B 76SER B 77MET B 80ASP B 98LEU B 99ALA B 114TRP B 116HIS B 119 | SAM B 300 |
3OU6_C_SAMC300 | 3ou6 | SAM DB00118(S-Adenosylmethionine) | Streptomycesluridus | SAM-DEPENDENTMETHYLTRANSFERASE | None | 15 | LEU C 12TYR C 15TYR C 22GLU C 52ALA C 54GLY C 56TRP C 60ASP C 75GLY C 76SER C 77MET C 80ASP C 98LEU C 99ALA C 114TRP C 116 | SAM C 300 |
3OU6_D_SAMD300 | 3ou6 | SAM DB00118(S-Adenosylmethionine) | Streptomycesluridus | SAM-DEPENDENTMETHYLTRANSFERASE | None | 14 | LEU D 12TYR D 15TYR D 22GLU D 52ALA D 54GLY D 56TRP D 60ASP D 75GLY D 76SER D 77MET D 80ASP D 98LEU D 99TRP D 116 | SAM D 300 |
3OU7_A_SAMA300 | 3ou7 | SAM DB00118(S-Adenosylmethionine) | Streptomycesluridus | SAM-DEPENDENTMETHYLTRANSFERASE | PF13649(Methyltransf_25) | 14 | LEU A 12TYR A 15TYR A 22ALA A 54GLY A 56TRP A 60ASP A 75GLY A 76SER A 77MET A 80ASP A 98LEU A 99TRP A 116HIS A 119 | SAM A 300 |
3OU7_B_SAMB300 | 3ou7 | SAM DB00118(S-Adenosylmethionine) | Streptomycesluridus | SAM-DEPENDENTMETHYLTRANSFERASE | None | 15 | LEU B 12TYR B 15TYR B 22ALA B 54GLY B 56TRP B 60ASP B 75GLY B 76SER B 77MET B 80ASP B 98LEU B 99ALA B 114TRP B 116HIS B 119 | SAM B 300 |
3OU7_C_SAMC300 | 3ou7 | SAM DB00118(S-Adenosylmethionine) | Streptomycesluridus | SAM-DEPENDENTMETHYLTRANSFERASE | None | 15 | LEU C 12TYR C 15TYR C 22ALA C 54GLY C 56TRP C 60ASP C 75GLY C 76SER C 77MET C 80ASP C 98LEU C 99ALA C 114TRP C 116HIS C 119 | SAM C 300 |
3OU7_D_SAMD300 | 3ou7 | SAM DB00118(S-Adenosylmethionine) | Streptomycesluridus | SAM-DEPENDENTMETHYLTRANSFERASE | None | 14 | LEU D 12TYR D 15TYR D 22ALA D 54GLY D 56TRP D 60ASP D 75GLY D 76SER D 77MET D 80ASP D 98LEU D 99TRP D 116HIS D 119 | SAM D 300 |