DRUG BINDING INTERFACES MAPPED TO 'S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
4KTT_A_SAMA405
4ktt
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
NonePF00438(S-AdoMet_synt_M)PF02772(S-AdoMet_synt_C)PF02773(S-AdoMet_synt_N)
16
HIS A 29PRO A 30ALA B 55GLU B 70GLN B 113ASP B 116ILE B 117ASP B 134ASP A 179LYS A 181SER A 206SER A 247PHE A 250ASP A 258LYS B 289ILE B 322
SAM A 405
4KTT_C_SAMC404
4ktt
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
None
16
HIS C 29PRO C 30ALA D 55GLU D 70GLN D 113ASP D 116ILE D 117ASP D 134ASP C 179LYS C 181SER C 206SER C 247PHE C 250ASP C 258LYS D 289ILE D 322
SAM C 404
4KTV_A_ADNA403
4ktv
ADN
DB00640(Adenosine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
PF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C)no annotation
12
HIS A 29PRO A 30ASP B 116ILE B 117ASP B 134ASP A 179LYS A 181SER A 206SER A 247PHE A 250ASP A 258ILE B 322
ADN A 403
4KTV_C_ADNC403
4ktv
ADN
DB00640(Adenosine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
no annotation
11
HIS C 29PRO C 30ASP D 116ILE D 117ASP D 134ASP C 179LYS C 181SER C 247PHE C 250ASP C 258ILE D 322
ADN C 403
4NDN_A_SAMA407
4ndn
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
NonePF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C)
16
HIS A 29PRO A 30ALA B 55GLU B 70GLN B 113ASP B 116ILE B 117ASP B 134ASP A 179LYS A 181SER A 206SER A 247PHE A 250ASP A 258LYS B 289ILE B 322
SAM A 407
4NDN_C_SAMC405
4ndn
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
None
15
HIS C 29PRO C 30ALA D 55GLU D 70GLN D 113ASP D 116ILE D 117ASP D 134ASP C 179LYS C 181SER C 247PHE C 250ASP C 258LYS D 289ILE D 322
SAM C 405
5A1I_A_ADNA407
5a1i
ADN
DB00640(Adenosine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
PF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C)
8
HIS A 29PRO A 30ASP A 179LYS A 181SER A 206SER A 247PHE A 250ASP A 258
ADN A 407
5A1I_A_SAMA405
5a1i
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
PF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C)
7
HIS A 29PRO A 30ASP A 179LYS A 181SER A 247PHE A 250ASP A 258
SAM A 405
6FBN_B_SAMB401
6fbn
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
NonePF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C)
15
HIS B 29PRO B 30ALA A 55GLU A 70ASP A 116ILE A 117ASP A 134ASP B 179LYS B 181SER B 206SER B 247PHE B 250ASP B 258LYS A 289ILE A 322
SAM B 401
6FBO_A_ADNA406
6fbo
ADN
DB00640(Adenosine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
PF00438(S-AdoMet_synt_C)PF02772(S-AdoMet_synt_N)PF02773(S-AdoMet_synt_M)
8
HIS A 29PRO A 30ASP A 179LYS A 181SER A 206SER A 247PHE A 250ASP A 258
ADN A 406
6FBP_B_ADNB404
6fbp
ADN
DB00640(Adenosine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
NonePF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C)
12
HIS B 29PRO B 30ASP A 116ILE A 117ASP A 134ASP B 179LYS B 181SER B 206SER B 247PHE B 250ASP B 258ILE A 322
ADN B 404
6FCB_A_SAMA405
6fcb
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
PF00438(S-AdoMet_synt_M)PF02772(S-AdoMet_synt_C)PF02773(S-AdoMet_synt_N)
8
HIS A 29PRO A 30ASP A 179LYS A 181SER A 206SER A 247PHE A 250ASP A 258
SAM A 405
6FCD_A_ADNA405
6fcd
ADN
DB00640(Adenosine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
PF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C)
8
HIS A 29PRO A 30ASP A 179LYS A 181SER A 206SER A 247PHE A 250ASP A 258
ADN A 405
6G6R_A_SAMA406
6g6r
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
S-ADENOSYLMETHIONINESYNTHASE ISOFORMTYPE-2
PF00438(S-AdoMet_synt_M)PF02772(S-AdoMet_synt_C)PF02773(S-AdoMet_synt_N)
7
HIS A 29PRO A 30ASP A 179LYS A 181SER A 247PHE A 250ASP A 258
SAM A 406
[["4KTT_A_SAMA405","4ktt","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","None;PF00438(S-AdoMet_synt_M);PF02772(S-AdoMet_synt_C);PF02773(S-AdoMet_synt_N)",16,"HIS A 29;PRO A 30;ALA B 55;GLU B 70;GLN B 113;ASP B 116;ILE B 117;ASP B 134;ASP A 179;LYS A 181;SER A 206;SER A 247;PHE A 250;ASP A 258;LYS B 289;ILE B 322","SAM A 405\r"],["4KTT_C_SAMC404","4ktt","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","None",16,"HIS C 29;PRO C 30;ALA D 55;GLU D 70;GLN D 113;ASP D 116;ILE D 117;ASP D 134;ASP C 179;LYS C 181;SER C 206;SER C 247;PHE C 250;ASP C 258;LYS D 289;ILE D 322","SAM C 404\r"],["4KTV_A_ADNA403","4ktv","ADN","DB00640(Adenosine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","PF00438(S-AdoMet_synt_N);PF02772(S-AdoMet_synt_M);PF02773(S-AdoMet_synt_C);no annotation",12,"HIS A 29;PRO A 30;ASP B 116;ILE B 117;ASP B 134;ASP A 179;LYS A 181;SER A 206;SER A 247;PHE A 250;ASP A 258;ILE B 322","ADN A 403\r"],["4KTV_C_ADNC403","4ktv","ADN","DB00640(Adenosine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","no annotation",11,"HIS C 29;PRO C 30;ASP D 116;ILE D 117;ASP D 134;ASP C 179;LYS C 181;SER C 247;PHE C 250;ASP C 258;ILE D 322","ADN C 403\r"],["4NDN_A_SAMA407","4ndn","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","None;PF00438(S-AdoMet_synt_N);PF02772(S-AdoMet_synt_M);PF02773(S-AdoMet_synt_C)",16,"HIS A 29;PRO A 30;ALA B 55;GLU B 70;GLN B 113;ASP B 116;ILE B 117;ASP B 134;ASP A 179;LYS A 181;SER A 206;SER A 247;PHE A 250;ASP A 258;LYS B 289;ILE B 322","SAM A 407\r"],["4NDN_C_SAMC405","4ndn","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","None",15,"HIS C 29;PRO C 30;ALA D 55;GLU D 70;GLN D 113;ASP D 116;ILE D 117;ASP D 134;ASP C 179;LYS C 181;SER C 247;PHE C 250;ASP C 258;LYS D 289;ILE D 322","SAM C 405\r"],["5A1I_A_ADNA407","5a1i","ADN","DB00640(Adenosine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","PF00438(S-AdoMet_synt_N);PF02772(S-AdoMet_synt_M);PF02773(S-AdoMet_synt_C)",8,"HIS A 29;PRO A 30;ASP A 179;LYS A 181;SER A 206;SER A 247;PHE A 250;ASP A 258","ADN A 407\r"],["5A1I_A_SAMA405","5a1i","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","PF00438(S-AdoMet_synt_N);PF02772(S-AdoMet_synt_M);PF02773(S-AdoMet_synt_C)",7,"HIS A 29;PRO A 30;ASP A 179;LYS A 181;SER A 247;PHE A 250;ASP A 258","SAM A 405\r"],["6FBN_B_SAMB401","6fbn","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","None;PF00438(S-AdoMet_synt_N);PF02772(S-AdoMet_synt_M);PF02773(S-AdoMet_synt_C)",15,"HIS B 29;PRO B 30;ALA A 55;GLU A 70;ASP A 116;ILE A 117;ASP A 134;ASP B 179;LYS B 181;SER B 206;SER B 247;PHE B 250;ASP B 258;LYS A 289;ILE A 322","SAM B 401\r"],["6FBO_A_ADNA406","6fbo","ADN","DB00640(Adenosine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","PF00438(S-AdoMet_synt_C);PF02772(S-AdoMet_synt_N);PF02773(S-AdoMet_synt_M)",8,"HIS A 29;PRO A 30;ASP A 179;LYS A 181;SER A 206;SER A 247;PHE A 250;ASP A 258","ADN A 406\r"],["6FBP_B_ADNB404","6fbp","ADN","DB00640(Adenosine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","None;PF00438(S-AdoMet_synt_N);PF02772(S-AdoMet_synt_M);PF02773(S-AdoMet_synt_C)",12,"HIS B 29;PRO B 30;ASP A 116;ILE A 117;ASP A 134;ASP B 179;LYS B 181;SER B 206;SER B 247;PHE B 250;ASP B 258;ILE A 322","ADN B 404\r"],["6FCB_A_SAMA405","6fcb","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","PF00438(S-AdoMet_synt_M);PF02772(S-AdoMet_synt_C);PF02773(S-AdoMet_synt_N)",8,"HIS A 29;PRO A 30;ASP A 179;LYS A 181;SER A 206;SER A 247;PHE A 250;ASP A 258","SAM A 405\r"],["6FCD_A_ADNA405","6fcd","ADN","DB00640(Adenosine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","PF00438(S-AdoMet_synt_N);PF02772(S-AdoMet_synt_M);PF02773(S-AdoMet_synt_C)",8,"HIS A 29;PRO A 30;ASP A 179;LYS A 181;SER A 206;SER A 247;PHE A 250;ASP A 258","ADN A 405\r"],["6G6R_A_SAMA406","6g6r","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","PF00438(S-AdoMet_synt_M);PF02772(S-AdoMet_synt_C);PF02773(S-AdoMet_synt_N)",7,"HIS A 29;PRO A 30;ASP A 179;LYS A 181;SER A 247;PHE A 250;ASP A 258","SAM A 406\r"]]