DRUG BINDING INTERFACES MAPPED TO 'RNA POLYMERASE SIGMA FACTOR RPOD'
List of Binding Interfaces
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(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
2A68_C_RBTC8001
2a68
RBT
DB00615(Rifabutin)
Thermusthermophilus
DNA-DIRECTED RNAPOLYMERASE BETACHAIN;RNA POLYMERASE SIGMAFACTOR RPOD
PF00140(Sigma70_r1_2)PF00562(RNA_pol_Rpb2_6)PF04539(Sigma70_r3)PF04542(Sigma70_r2)PF04545(Sigma70_r4)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF10385(RNA_pol_Rpb2_45)
11
ARG C 134ASP F 323GLN C 390GLN C 393PHE C 394ASP C 396HIS C 406ARG C 409SER C 411PRO C 444ILE C 452
RBT C8001
2A68_M_RBTM8002
2a68
RBT
DB00615(Rifabutin)
Thermusthermophilus
DNA-DIRECTED RNAPOLYMERASE BETACHAIN;RNA POLYMERASE SIGMAFACTOR RPOD
no annotation
13
ARG M 134ASP P 323LYS P 325GLN M 390GLN M 393PHE M 394ASP M 396HIS M 406ARG M 409SER M 411PRO M 444ILE M 452ASN M 563
RBT M8002
2A69_C_RPTC8001
2a69
RPT
DB01201(Rifapentine)
Thermusthermophilus
DNA-DIRECTED RNAPOLYMERASE BETACHAIN;RNA POLYMERASE SIGMAFACTOR RPOD
PF00140(Sigma70_r1_2)PF00562(RNA_pol_Rpb2_6)PF04539(Sigma70_r3)PF04542(Sigma70_r2)PF04545(Sigma70_r4)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF10385(RNA_pol_Rpb2_45)
11
ARG C 134ASP F 323GLN C 390GLN C 393PHE C 394ASP C 396HIS C 406ARG C 409SER C 411PRO C 444ILE C 452
RPT C8001
4KMU_H_RFPH1401
4kmu
RFP
DB01045(Rifampicin)
Escherichia coli
DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA;RNA POLYMERASE SIGMAFACTOR RPOD
no annotation
14
GLN H 510GLN H 513ASP Y 514PHE H 514ASP H 516HIS H 526ARG H 529SER H 531LEU H 533ARG H 540PRO H 564ASN H 568ILE H 572ARG H 687
RFP H1401
[["2A68_C_RBTC8001","2a68","RBT","DB00615(Rifabutin)","Thermus thermophilus","DNA-DIRECTED RNA POLYMERASE BETA CHAIN;RNA POLYMERASE SIGMA FACTOR RPOD","PF00140(Sigma70_r1_2);PF00562(RNA_pol_Rpb2_6);PF04539(Sigma70_r3);PF04542(Sigma70_r2);PF04545(Sigma70_r4);PF04560(RNA_pol_Rpb2_7);PF04561(RNA_pol_Rpb2_2);PF04563(RNA_pol_Rpb2_1);PF04565(RNA_pol_Rpb2_3);PF10385(RNA_pol_Rpb2_45)",11,"ARG C 134;ASP F 323;GLN C 390;GLN C 393;PHE C 394;ASP C 396;HIS C 406;ARG C 409;SER C 411;PRO C 444;ILE C 452","RBT C8001\r"],["2A68_M_RBTM8002","2a68","RBT","DB00615(Rifabutin)","Thermus thermophilus","DNA-DIRECTED RNA POLYMERASE BETA CHAIN;RNA POLYMERASE SIGMA FACTOR RPOD","no annotation",13,"ARG M 134;ASP P 323;LYS P 325;GLN M 390;GLN M 393;PHE M 394;ASP M 396;HIS M 406;ARG M 409;SER M 411;PRO M 444;ILE M 452;ASN M 563","RBT M8002\r"],["2A69_C_RPTC8001","2a69","RPT","DB01201(Rifapentine)","Thermus thermophilus","DNA-DIRECTED RNA POLYMERASE BETA CHAIN;RNA POLYMERASE SIGMA FACTOR RPOD","PF00140(Sigma70_r1_2);PF00562(RNA_pol_Rpb2_6);PF04539(Sigma70_r3);PF04542(Sigma70_r2);PF04545(Sigma70_r4);PF04560(RNA_pol_Rpb2_7);PF04561(RNA_pol_Rpb2_2);PF04563(RNA_pol_Rpb2_1);PF04565(RNA_pol_Rpb2_3);PF10385(RNA_pol_Rpb2_45)",11,"ARG C 134;ASP F 323;GLN C 390;GLN C 393;PHE C 394;ASP C 396;HIS C 406;ARG C 409;SER C 411;PRO C 444;ILE C 452","RPT C8001\r"],["4KMU_H_RFPH1401","4kmu","RFP","DB01045(Rifampicin)","Escherichia coli","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;RNA POLYMERASE SIGMA FACTOR RPOD","no annotation",14,"GLN H 510;GLN H 513;ASP Y 514;PHE H 514;ASP H 516;HIS H 526;ARG H 529;SER H 531;LEU H 533;ARG H 540;PRO H 564;ASN H 568;ILE H 572;ARG H 687","RFP H1401\r"]]