DRUG BINDING INTERFACES MAPPED TO 'RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
3V8V_A_SAMA801 3v8v SAM

DB00118
(S-
Adenosylmethionine)
Escherichia coli RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L
PF01170
(THUMP)
PF02926
(Methyltrans_SAM)
PF10672
(UPF0020)
14 PRO A 172
ILE A 173
MET A 197
GLY A 199
SER A 200
THR A 202
ASP A 262
SER A 263
ASP A 264
ASP A 290
VAL A 291
ASN A 309
PRO A 311
LEU A 325
SAM A 801
3V8V_A_SAMA802 3v8v SAM

DB00118
(S-
Adenosylmethionine)
Escherichia coli RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L
PF01170
(THUMP)
PF02926
(Methyltrans_SAM)
PF10672
(UPF0020)
9 PHE A 546
TYR A 548
ASP A 568
MET A 569
SER A 570
TYR A 573
ASP A 597
CYS A 598
PRO A 617
SAM A 802
3V8V_B_SAMB801 3v8v SAM

DB00118
(S-
Adenosylmethionine)
Escherichia coli RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L
None 11 MET B 197
GLY B 199
ASP B 262
SER B 263
ASP B 264
ASP B 290
VAL B 291
ASN B 309
PRO B 311
TYR B 312
LEU B 325
SAM B 801
3V8V_B_SAMB802 3v8v SAM

DB00118
(S-
Adenosylmethionine)
Escherichia coli RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L
None 13 ARG B 530
PHE B 546
TYR B 548
SER B 551
ASP B 568
MET B 569
SER B 570
TYR B 573
ASP B 597
CYS B 598
ASP B 615
PRO B 617
SER B 620
SAM B 802