DRUG BINDING INTERFACES MAPPED TO 'RETINOIC ACID RECEPTOR RXR-ALPHA'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1FBY_A_9CRA500 | 1fby | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 13 | ILE A 268CYS A 269ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435 | 9CR A 500 |
1FBY_B_9CRB1500 | 1fby | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 13 | ILE B1268CYS B1269ALA B1271ALA B1272GLN B1275PHE B1313ARG B1316LEU B1326ALA B1327VAL B1342ILE B1345CYS B1432HIS B1435 | 9CR B1500 |
1FM6_A_9CRA501 | 1fm6 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A 501 |
1FM6_U_9CRU502 | 1fm6 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 12 | ALA U 271ALA U 272TRP U 305PHE U 313ARG U 316LEU U 326ALA U 327VAL U 342ILE U 345CYS U 432HIS U 435LEU U 436 | 9CR U 502 |
1FM9_A_9CRA201 | 1fm9 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 15 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A 201 |
1G5Y_B_9CRB501 | 1g5y | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE B 268ALA B 272GLN B 275LEU B 276TRP B 305LEU B 309PHE B 313ARG B 316LEU B 326ALA B 327PHE B 438PHE B 439LEU B 441ILE B 442 | 9CR B 501 |
1G5Y_C_9CRC502 | 1g5y | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 10 | ALA C 272LEU C 309SER C 312PHE C 313ARG C 316LEU C 326ALA C 327PHE C 438PHE C 439ILE C 442 | 9CR C 502 |
1K74_A_9CRA463 | 1k74 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 15 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A 463 |
1XDK_A_9CRA500 | 1xdk | 9CR DB00523(Alitretinoin) | Mus musculus | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 273ALA A 276GLN A 280TRP A 310ASN A 311PHE A 318ARG A 321LEU A 331ALA A 332VAL A 347ILE A 350CYS A 437HIS A 440LEU A 441 | 9CR A 500 |
1XDK_E_9CRE1500 | 1xdk | 9CR DB00523(Alitretinoin) | Mus musculus | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE E 273ALA E 276ALA E 277GLN E 280TRP E 310ASN E 311PHE E 318ARG E 321LEU E 331ALA E 332VAL E 347CYS E 437HIS E 440LEU E 441 | 9CR E1500 |
1XLS_A_9CRA801 | 1xls | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432HIS A 435LEU A 436 | 9CR A 801 |
1XLS_B_9CRB802 | 1xls | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE B 268ALA B 271ALA B 272GLN B 275TRP B 305LEU B 309PHE B 313ARG B 316LEU B 326ALA B 327VAL B 342CYS B 432HIS B 435LEU B 436 | 9CR B 802 |
1XLS_C_9CRC803 | 1xls | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE C 268ALA C 271ALA C 272GLN C 275TRP C 305LEU C 309PHE C 313ARG C 316LEU C 326ALA C 327VAL C 342CYS C 432HIS C 435LEU C 436 | 9CR C 803 |
1XLS_D_9CRD804 | 1xls | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE D 268ALA D 271ALA D 272GLN D 275TRP D 305LEU D 309PHE D 313ARG D 316LEU D 326ALA D 327VAL D 342CYS D 432HIS D 435LEU D 436 | 9CR D 804 |
2ACL_A_REAA502 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)no annotation | 12 | ALA A 271ALA A 272GLN A 275ASN A 306LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345CYS A 432LEU E 436 | REA A 502 |
2ACL_C_REAC503 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 10 | ILE C 268ALA C 271ALA C 272GLN C 275ASN C 306PHE C 313ARG C 316ALA C 327ILE C 345CYS C 432 | REA C 503 |
2ACL_E_REAE504 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 11 | ILE E 268ALA E 271ALA E 272GLN E 275ASN E 306LEU E 309PHE E 313ARG E 316ALA E 327ILE E 345CYS E 432 | REA E 504 |
2ACL_G_REAG501 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 13 | ILE G 268ALA G 271ALA G 272GLN G 275ASN G 306LEU G 309ILE G 310PHE G 313ARG G 316LEU G 326ALA G 327CYS G 432LEU C 436 | REA G 501 |
3DZU_A_9CRA7223 | 3dzu | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)PF00105(zf-C4) | 13 | ILE A 268ALA A 271GLN A 275ASN A 306ILE A 310PHE A 313ARG A 316LEU A 326VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A7223 |
3DZY_A_9CRA463 | 3dzy | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)PF00105(zf-C4) | 13 | ILE A 268ALA A 271GLN A 275ASN A 306SER A 312PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432HIS A 435LEU A 436 | 9CR A 463 |
3E00_A_9CRA7223 | 3e00 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)PF00105(zf-C4) | 13 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305ASN A 306PHE A 313ARG A 316ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435 | 9CR A7223 |
3FAL_A_REAA501 | 3fal | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 10 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316ALA A 327VAL A 342ILE A 345CYS A 432 | REA A 501 |
3FAL_C_REAC501 | 3fal | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 10 | ILE C 268ALA C 271ALA C 272GLN C 275PHE C 313ARG C 316LEU C 326ALA C 327ILE C 345CYS C 432 | REA C 501 |
3FC6_A_REAA501 | 3fc6 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 11 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345CYS A 432 | REA A 501 |
3FC6_C_REAC501 | 3fc6 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | VAL C 265CYS C 269ALA C 271ALA C 272GLN C 275ASN C 306LEU C 309PHE C 313ARG C 316LEU C 326ALA C 327VAL C 342ILE C 345CYS C 432 | REA C 501 |
3H0A_A_9RAA500 | 3h0a | 9RA DB00307(Bexarotene) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 15 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9RA A 500 |
3OAP_A_9CRA500 | 3oap | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 268ALA A 271ALA A 272GLN A 275LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A 500 |
3UVV_B_9CRB501 | 3uvv | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 12 | ILE B 268ALA B 271ALA B 272GLN B 275LEU B 309PHE B 313ARG B 316ALA B 327VAL B 342ILE B 345CYS B 432LEU B 436 | 9CR B 501 |
4K6I_A_9RAA500 | 4k6i | 9RA DB00307(Bexarotene) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 268ALA A 271ALA A 272GLN A 275LEU A 309ILE A 310PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345VAL A 349CYS A 432HIS A 435 | 9RA A 500 |
4NQA_A_9CRA501 | 4nqa | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)PF00105(zf-C4) | 11 | ILE A 268ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432HIS A 435LEU A 436 | 9CR A 501 |
4NQA_H_9CRH501 | 4nqa | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 12 | ILE H 268ALA H 271ALA H 272GLN H 275PHE H 313ARG H 316LEU H 326ALA H 327ILE H 345CYS H 432HIS H 435LEU H 436 | 9CR H 501 |
5JI0_A_9CRA501 | 5ji0 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 11 | ILE A 268GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432LEU A 436 | 9CR A 501 |
5UAN_A_9CRA503 | 5uan | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 13 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432LEU A 436 | 9CR A 503 |
5Z12_B_9CRB501 | 5z12 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 15 | ILE B 268ALA B 271ALA B 272GLN B 275TRP B 305LEU B 309PHE B 313ARG B 316LEU B 326ALA B 327VAL B 342ILE B 345CYS B 432HIS B 435LEU B 436 | 9CR B 501 |
5Z12_C_9CRC501 | 5z12 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 13 | ILE C 268ALA C 271ALA C 272GLN C 275TRP C 305PHE C 313ARG C 316LEU C 326ALA C 327VAL C 342ILE C 345CYS C 432LEU C 436 | 9CR C 501 |
6A5Y_D_9CRD501 | 6a5y | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 15 | ILE D 268ALA D 271ALA D 272GLN D 275TRP D 305ASN D 306PHE D 313ARG D 316LEU D 326ALA D 327VAL D 342ILE D 345CYS D 432HIS D 435LEU D 436 | 9CR D 501 |
6A5Z_D_9CRD501 | 6a5z | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 13 | ILE D 268ALA D 271ALA D 272GLN D 275ILE D 310PHE D 313ARG D 316LEU D 326ALA D 327ILE D 345CYS D 432HIS D 435LEU D 436 | 9CR D 501 |
6A5Z_L_9CRL501 | 6a5z | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | None | 14 | ILE L 268ALA L 271ALA L 272GLN L 275TRP L 305ILE L 310PHE L 313ARG L 316LEU L 326ALA L 327ILE L 345CYS L 432HIS L 435LEU L 436 | 9CR L 501 |
6A60_D_9CRD501 | 6a60 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE D 268ALA D 271ALA D 272GLN D 275LEU D 309ILE D 310PHE D 313ARG D 316LEU D 326ALA D 327ILE D 345CYS D 432HIS D 435LEU D 436 | 9CR D 501 |