DRUG BINDING INTERFACES MAPPED TO 'RETINOIC ACID RECEPTOR'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1FBY_A_9CRA500 | 1fby | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 13 | ILE A 268CYS A 269ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435 | 9CR A 500 |
1FBY_B_9CRB1500 | 1fby | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 13 | ILE B1268CYS B1269ALA B1271ALA B1272GLN B1275PHE B1313ARG B1316LEU B1326ALA B1327VAL B1342ILE B1345CYS B1432HIS B1435 | 9CR B1500 |
1FM6_A_9CRA501 | 1fm6 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A 501 |
1FM6_U_9CRU502 | 1fm6 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 12 | ALA U 271ALA U 272TRP U 305PHE U 313ARG U 316LEU U 326ALA U 327VAL U 342ILE U 345CYS U 432HIS U 435LEU U 436 | 9CR U 502 |
1FM9_A_9CRA201 | 1fm9 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 15 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A 201 |
1G5Y_B_9CRB501 | 1g5y | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE B 268ALA B 272GLN B 275LEU B 276TRP B 305LEU B 309PHE B 313ARG B 316LEU B 326ALA B 327PHE B 438PHE B 439LEU B 441ILE B 442 | 9CR B 501 |
1G5Y_C_9CRC502 | 1g5y | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 10 | ALA C 272LEU C 309SER C 312PHE C 313ARG C 316LEU C 326ALA C 327PHE C 438PHE C 439ILE C 442 | 9CR C 502 |
1K74_A_9CRA463 | 1k74 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 15 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A 463 |
1XDK_A_9CRA500 | 1xdk | 9CR DB00523(Alitretinoin) | Mus musculus | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 273ALA A 276GLN A 280TRP A 310ASN A 311PHE A 318ARG A 321LEU A 331ALA A 332VAL A 347ILE A 350CYS A 437HIS A 440LEU A 441 | 9CR A 500 |
1XDK_B_9CRB600 | 1xdk | 9CR DB00523(Alitretinoin) | Mus musculus | RETINOIC ACIDRECEPTOR, BETA | PF00104(Hormone_recep) | 15 | PHE B 221LEU B 224ALA B 225CYS B 228LEU B 259LEU B 262ILE B 263ILE B 266ARG B 269PHE B 279SER B 280PHE B 295LEU B 298ARG B 387LEU B 407 | 9CR B 600 |
1XDK_E_9CRE1500 | 1xdk | 9CR DB00523(Alitretinoin) | Mus musculus | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE E 273ALA E 276ALA E 277GLN E 280TRP E 310ASN E 311PHE E 318ARG E 321LEU E 331ALA E 332VAL E 347CYS E 437HIS E 440LEU E 441 | 9CR E1500 |
1XDK_F_9CRF1600 | 1xdk | 9CR DB00523(Alitretinoin) | Mus musculus | RETINOIC ACIDRECEPTOR, BETA | no annotation | 15 | PHE F 221LEU F 224ALA F 225CYS F 228LEU F 259LEU F 262ILE F 263ILE F 266ARG F 269PHE F 279SER F 280PHE F 295LEU F 298ARG F 387LEU F 407 | 9CR F1600 |
1XLS_A_9CRA801 | 1xls | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432HIS A 435LEU A 436 | 9CR A 801 |
1XLS_B_9CRB802 | 1xls | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE B 268ALA B 271ALA B 272GLN B 275TRP B 305LEU B 309PHE B 313ARG B 316LEU B 326ALA B 327VAL B 342CYS B 432HIS B 435LEU B 436 | 9CR B 802 |
1XLS_C_9CRC803 | 1xls | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE C 268ALA C 271ALA C 272GLN C 275TRP C 305LEU C 309PHE C 313ARG C 316LEU C 326ALA C 327VAL C 342CYS C 432HIS C 435LEU C 436 | 9CR C 803 |
1XLS_D_9CRD804 | 1xls | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | ILE D 268ALA D 271ALA D 272GLN D 275TRP D 305LEU D 309PHE D 313ARG D 316LEU D 326ALA D 327VAL D 342CYS D 432HIS D 435LEU D 436 | 9CR D 804 |
2ACL_A_REAA502 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)no annotation | 12 | ALA A 271ALA A 272GLN A 275ASN A 306LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345CYS A 432LEU E 436 | REA A 502 |
2ACL_C_REAC503 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 10 | ILE C 268ALA C 271ALA C 272GLN C 275ASN C 306PHE C 313ARG C 316ALA C 327ILE C 345CYS C 432 | REA C 503 |
2ACL_E_REAE504 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 11 | ILE E 268ALA E 271ALA E 272GLN E 275ASN E 306LEU E 309PHE E 313ARG E 316ALA E 327ILE E 345CYS E 432 | REA E 504 |
2ACL_G_REAG501 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 13 | ILE G 268ALA G 271ALA G 272GLN G 275ASN G 306LEU G 309ILE G 310PHE G 313ARG G 316LEU G 326ALA G 327CYS G 432LEU C 436 | REA G 501 |
2LBD_A_REAA500 | 2lbd | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR GAMMA | PF00104(Hormone_recep) | 12 | PHE A 230LYS A 236CYS A 237LEU A 271MET A 272ARG A 274ILE A 275ARG A 278PHE A 288SER A 289GLY A 393LEU A 400 | REA A 500 |
3A9E_B_REAB1 | 3a9e | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR ALPHA | PF00104(Hormone_recep) | 11 | PHE B 228SER B 232CYS B 235LEU B 269ILE B 273ARG B 276PHE B 286SER B 287PHE B 302VAL B 395LEU B 398 | REA B 1 |
3DZU_A_9CRA7223 | 3dzu | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)PF00105(zf-C4) | 13 | ILE A 268ALA A 271GLN A 275ASN A 306ILE A 310PHE A 313ARG A 316LEU A 326VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A7223 |
3DZY_A_9CRA463 | 3dzy | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)PF00105(zf-C4) | 13 | ILE A 268ALA A 271GLN A 275ASN A 306SER A 312PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432HIS A 435LEU A 436 | 9CR A 463 |
3E00_A_9CRA7223 | 3e00 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)PF00105(zf-C4) | 13 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305ASN A 306PHE A 313ARG A 316ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435 | 9CR A7223 |
3FAL_A_REAA501 | 3fal | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 10 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316ALA A 327VAL A 342ILE A 345CYS A 432 | REA A 501 |
3FAL_C_REAC501 | 3fal | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 10 | ILE C 268ALA C 271ALA C 272GLN C 275PHE C 313ARG C 316LEU C 326ALA C 327ILE C 345CYS C 432 | REA C 501 |
3FC6_A_REAA501 | 3fc6 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 11 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345CYS A 432 | REA A 501 |
3FC6_C_REAC501 | 3fc6 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | VAL C 265CYS C 269ALA C 271ALA C 272GLN C 275ASN C 306LEU C 309PHE C 313ARG C 316LEU C 326ALA C 327VAL C 342ILE C 345CYS C 432 | REA C 501 |
3H0A_A_9RAA500 | 3h0a | 9RA DB00307(Bexarotene) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 15 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9RA A 500 |
3LBD_A_9CRA424 | 3lbd | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR GAMMA | PF00104(Hormone_recep) | 14 | PHE A 230ALA A 234LEU A 268LEU A 271MET A 272ILE A 275ARG A 278PHE A 288SER A 289PHE A 304GLY A 393ALA A 397LEU A 400ILE A 412 | 9CR A 424 |
3OAP_A_9CRA500 | 3oap | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 268ALA A 271ALA A 272GLN A 275LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342ILE A 345CYS A 432HIS A 435LEU A 436 | 9CR A 500 |
3UVV_B_9CRB501 | 3uvv | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 12 | ILE B 268ALA B 271ALA B 272GLN B 275LEU B 309PHE B 313ARG B 316ALA B 327VAL B 342ILE B 345CYS B 432LEU B 436 | 9CR B 501 |
4DM8_A_REAA501 | 4dm8 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR BETA | PF00104(Hormone_recep) | 11 | PHE A 230CYS A 237LEU A 268LEU A 271ILE A 272ARG A 278PHE A 288SER A 289LEU A 307LEU A 400ILE A 412 | REA A 501 |
4DM8_B_REAB1501 | 4dm8 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR BETA | no annotation | 14 | PHE B1201PHE B1230LEU B1233ALA B1234LEU B1268LEU B1271ILE B1272ARG B1278PHE B1288SER B1289PHE B1304LEU B1307GLY B1393LEU B1400 | REA B1501 |
4K6I_A_9RAA500 | 4k6i | 9RA DB00307(Bexarotene) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE A 268ALA A 271ALA A 272GLN A 275LEU A 309ILE A 310PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345VAL A 349CYS A 432HIS A 435 | 9RA A 500 |
4NQA_A_9CRA501 | 4nqa | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)PF00105(zf-C4) | 11 | ILE A 268ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432HIS A 435LEU A 436 | 9CR A 501 |
4NQA_H_9CRH501 | 4nqa | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 12 | ILE H 268ALA H 271ALA H 272GLN H 275PHE H 313ARG H 316LEU H 326ALA H 327ILE H 345CYS H 432HIS H 435LEU H 436 | 9CR H 501 |
5JI0_A_9CRA501 | 5ji0 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 11 | ILE A 268GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432LEU A 436 | 9CR A 501 |
5M24_A_9CRA501 | 5m24 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR GAMMA | PF00104(Hormone_recep) | 14 | TRP A 227PHE A 230ALA A 234LEU A 268LEU A 271MET A 272ILE A 275ARG A 278PHE A 288SER A 289PHE A 304GLY A 393LEU A 400ILE A 412 | 9CR A 501 |
5UAN_A_9CRA503 | 5uan | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 13 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYS A 432LEU A 436 | 9CR A 503 |
5UAN_B_REAB503 | 5uan | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR BETA | no annotation | 13 | PHE B 221ALA B 225CYS B 228LEU B 259LEU B 262ILE B 263ILE B 266PHE B 279SER B 280PHE B 295LEU B 298VAL B 388LEU B 391 | REA B 503 |
5Z12_B_9CRB501 | 5z12 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 15 | ILE B 268ALA B 271ALA B 272GLN B 275TRP B 305LEU B 309PHE B 313ARG B 316LEU B 326ALA B 327VAL B 342ILE B 345CYS B 432HIS B 435LEU B 436 | 9CR B 501 |
5Z12_C_9CRC501 | 5z12 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 13 | ILE C 268ALA C 271ALA C 272GLN C 275TRP C 305PHE C 313ARG C 316LEU C 326ALA C 327VAL C 342ILE C 345CYS C 432LEU C 436 | 9CR C 501 |
6A5Y_D_9CRD501 | 6a5y | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 15 | ILE D 268ALA D 271ALA D 272GLN D 275TRP D 305ASN D 306PHE D 313ARG D 316LEU D 326ALA D 327VAL D 342ILE D 345CYS D 432HIS D 435LEU D 436 | 9CR D 501 |
6A5Z_D_9CRD501 | 6a5z | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 13 | ILE D 268ALA D 271ALA D 272GLN D 275ILE D 310PHE D 313ARG D 316LEU D 326ALA D 327ILE D 345CYS D 432HIS D 435LEU D 436 | 9CR D 501 |
6A5Z_L_9CRL501 | 6a5z | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | None | 14 | ILE L 268ALA L 271ALA L 272GLN L 275TRP L 305ILE L 310PHE L 313ARG L 316LEU L 326ALA L 327ILE L 345CYS L 432HIS L 435LEU L 436 | 9CR L 501 |
6A60_D_9CRD501 | 6a60 | 9CR DB00523(Alitretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 14 | ILE D 268ALA D 271ALA D 272GLN D 275LEU D 309ILE D 310PHE D 313ARG D 316LEU D 326ALA D 327ILE D 345CYS D 432HIS D 435LEU D 436 | 9CR D 501 |
6EU9_B_REAB601 | 6eu9 | REA DB00755(Tretinoin) | Platynereisdumerilii | RETINOIC ACIDRECEPTOR | no annotation | 10 | ARG B 355VAL B 356LEU B 359SER B 360LEU B 394PHE B 414GLY B 428GLY B 519ARG B 522VAL B 523 | REA B 601 |
6EU9_D_READ601 | 6eu9 | REA DB00755(Tretinoin) | Platynereisdumerilii | RETINOIC ACIDRECEPTOR | no annotation | 7 | VAL D 356LEU D 394PHE D 414LEU D 420GLY D 428LEU D 433GLY D 519 | REA D 601 |