DRUG BINDING INTERFACES MAPPED TO 'PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC'

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
2OIQ_A_STIA1001	2oiq	STI DB00619 (Imatinib)	Gallus gallus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	PF07714 (Pkinase_Tyr)	17	LEU A 273 VAL A 281 ALA A 293 LYS A 295 GLU A 310 VAL A 313 MET A 314 LEU A 317 ILE A 336 THR A 338 TYR A 340 MET A 341 GLY A 344 ARG A 385 LEU A 393 ALA A 403 ASP A 404	STI A1001
3G5D_A_1N1A1	3g5d	1N1 DB01254 (Dasatinib)	Gallus gallus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	PF07714 (Pkinase_Tyr)	14	LEU A 273 VAL A 281 ALA A 293 LYS A 295 GLU A 310 MET A 314 VAL A 323 ILE A 336 THR A 338 TYR A 340 MET A 341 GLY A 344 LEU A 393 ALA A 403	1N1 A 1
3G5D_B_1N1B1	3g5d	1N1 DB01254 (Dasatinib)	Gallus gallus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	no annotation	14	LEU B 273 VAL B 281 ALA B 293 LYS B 295 GLU B 310 MET B 314 VAL B 323 ILE B 336 THR B 338 TYR B 340 MET B 341 GLY B 344 LEU B 393 ALA B 403	1N1 B 1
3OEZ_A_STIA601	3oez	STI DB00619 (Imatinib)	Gallus gallus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	PF07714 (Pkinase_Tyr)	17	VAL A 281 ALA A 293 LYS A 295 GLU A 310 VAL A 313 MET A 314 ILE A 317 VAL A 323 ILE A 336 THR A 338 TYR A 340 MET A 341 GLY A 344 ARG A 385 LEU A 393 ALA A 403 ASP A 404	STI A 601
3OEZ_B_STIB601	3oez	STI DB00619 (Imatinib)	Gallus gallus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	no annotation	14	VAL B 281 ALA B 293 LYS B 295 GLU B 310 VAL B 313 MET B 314 ILE B 336 THR B 338 TYR B 340 MET B 341 ARG B 385 LEU B 393 ALA B 403 ASP B 404	STI B 601
3QLG_A_1N1A601	3qlg	1N1 DB01254 (Dasatinib)	Gallus gallus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	PF07714 (Pkinase_Tyr)	14	LEU A 273 VAL A 281 ALA A 293 LYS A 295 GLU A 310 MET A 314 VAL A 323 ILE A 336 THR A 338 TYR A 340 MET A 341 GLY A 344 LEU A 393 ALA A 403	1N1 A 601
3QLG_B_1N1B601	3qlg	1N1 DB01254 (Dasatinib)	Gallus gallus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	no annotation	16	LEU B 273 VAL B 281 ALA B 293 LYS B 295 GLU B 310 MET B 314 VAL B 323 ILE B 336 THR B 338 TYR B 340 MET B 341 LYS B 343 GLY B 344 LEU B 393 ALA B 403 ASP B 404	1N1 B 601
4MXO_A_DB8A601	4mxo	DB8 DB06616 (Bosutinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	PF07714 (Pkinase_Tyr)	14	LEU A 273 VAL A 281 ALA A 293 LYS A 295 GLU A 310 MET A 314 VAL A 323 ILE A 336 THR A 338 TYR A 340 MET A 341 GLY A 344 LEU A 393 ASP A 404	DB8 A 601
4MXO_B_DB8B601	4mxo	DB8 DB06616 (Bosutinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	no annotation	13	LEU B 273 VAL B 281 ALA B 293 LYS B 295 GLU B 310 VAL B 323 ILE B 336 THR B 338 TYR B 340 MET B 341 GLY B 344 LEU B 393 ASP B 404	DB8 B 601
4MXX_A_DB8A601	4mxx	DB8 DB06616 (Bosutinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	PF07714 (Pkinase_Tyr)	13	LEU A 273 ALA A 293 LYS A 295 GLU A 310 MET A 314 VAL A 323 ILE A 336 THR A 338 TYR A 340 MET A 341 GLY A 344 LEU A 393 THR A 403	DB8 A 601
4MXX_B_DB8B601	4mxx	DB8 DB06616 (Bosutinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	no annotation	12	LEU B 273 VAL B 281 ALA B 293 LYS B 295 VAL B 323 THR B 338 TYR B 340 MET B 341 GLY B 344 LEU B 393 THR B 403 PHE B 405	DB8 B 601
4MXY_A_DB8A601	4mxy	DB8 DB06616 (Bosutinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	PF07714 (Pkinase_Tyr)	13	LEU A 273 VAL A 281 ALA A 293 LYS A 295 GLU A 310 VAL A 323 ILE A 336 MET A 338 TYR A 340 MET A 341 GLY A 344 LEU A 393 ASP A 404	DB8 A 601
4MXY_B_DB8B601	4mxy	DB8 DB06616 (Bosutinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	no annotation	13	LEU B 273 VAL B 281 ALA B 293 LYS B 295 GLU B 310 VAL B 323 MET B 338 TYR B 340 MET B 341 GLY B 344 LEU B 393 ALA B 403 ASP B 404	DB8 B 601
4MXZ_A_DB8A601	4mxz	DB8 DB06616 (Bosutinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	PF07714 (Pkinase_Tyr)	13	LEU A 273 VAL A 281 ALA A 293 LYS A 295 GLU A 310 VAL A 323 ILE A 336 MET A 338 TYR A 340 MET A 341 GLY A 344 LEU A 393 ASP A 404	DB8 A 601
4MXZ_B_DB8B601	4mxz	DB8 DB06616 (Bosutinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	no annotation	13	LEU B 273 VAL B 281 ALA B 293 LYS B 295 GLU B 310 VAL B 323 MET B 338 TYR B 340 MET B 341 GLY B 344 LEU B 393 ALA B 403 ASP B 404	DB8 B 601
4U5J_A_RXTA601	4u5j	RXT DB08877 (Ruxolitinib)	Gallus gallus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	PF07714 (Pkinase_Tyr)	11	LEU A 273 GLY A 276 VAL A 281 ALA A 293 TYR A 340 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403 ASP A 404	RXT A 601
4U5J_B_RXTB601	4u5j	RXT DB08877 (Ruxolitinib)	Gallus gallus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC	no annotation	9	LEU B 273 VAL B 281 ALA B 293 LYS B 295 TYR B 340 MET B 341 GLY B 344 LEU B 393 ASP B 404	RXT B 601

[["2OIQ_A_STIA1001","2oiq","STI","DB00619(Imatinib)","Gallus gallus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","PF07714(Pkinase_Tyr)",17,"LEU A 273;VAL A 281;ALA A 293;LYS A 295;GLU A 310;VAL A 313;MET A 314;LEU A 317;ILE A 336;THR A 338;TYR A 340;MET A 341;GLY A 344;ARG A 385;LEU A 393;ALA A 403;ASP A 404","STI A1001\r"],["3G5D_A_1N1A1","3g5d","1N1","DB01254(Dasatinib)","Gallus gallus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","PF07714(Pkinase_Tyr)",14,"LEU A 273;VAL A 281;ALA A 293;LYS A 295;GLU A 310;MET A 314;VAL A 323;ILE A 336;THR A 338;TYR A 340;MET A 341;GLY A 344;LEU A 393;ALA A 403","1N1 A   1\r"],["3G5D_B_1N1B1","3g5d","1N1","DB01254(Dasatinib)","Gallus gallus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","no annotation",14,"LEU B 273;VAL B 281;ALA B 293;LYS B 295;GLU B 310;MET B 314;VAL B 323;ILE B 336;THR B 338;TYR B 340;MET B 341;GLY B 344;LEU B 393;ALA B 403","1N1 B   1\r"],["3OEZ_A_STIA601","3oez","STI","DB00619(Imatinib)","Gallus gallus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","PF07714(Pkinase_Tyr)",17,"VAL A 281;ALA A 293;LYS A 295;GLU A 310;VAL A 313;MET A 314;ILE A 317;VAL A 323;ILE A 336;THR A 338;TYR A 340;MET A 341;GLY A 344;ARG A 385;LEU A 393;ALA A 403;ASP A 404","STI A 601\r"],["3OEZ_B_STIB601","3oez","STI","DB00619(Imatinib)","Gallus gallus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","no annotation",14,"VAL B 281;ALA B 293;LYS B 295;GLU B 310;VAL B 313;MET B 314;ILE B 336;THR B 338;TYR B 340;MET B 341;ARG B 385;LEU B 393;ALA B 403;ASP B 404","STI B 601\r"],["3QLG_A_1N1A601","3qlg","1N1","DB01254(Dasatinib)","Gallus gallus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","PF07714(Pkinase_Tyr)",14,"LEU A 273;VAL A 281;ALA A 293;LYS A 295;GLU A 310;MET A 314;VAL A 323;ILE A 336;THR A 338;TYR A 340;MET A 341;GLY A 344;LEU A 393;ALA A 403","1N1 A 601\r"],["3QLG_B_1N1B601","3qlg","1N1","DB01254(Dasatinib)","Gallus gallus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","no annotation",16,"LEU B 273;VAL B 281;ALA B 293;LYS B 295;GLU B 310;MET B 314;VAL B 323;ILE B 336;THR B 338;TYR B 340;MET B 341;LYS B 343;GLY B 344;LEU B 393;ALA B 403;ASP B 404","1N1 B 601\r"],["4MXO_A_DB8A601","4mxo","DB8","DB06616(Bosutinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","PF07714(Pkinase_Tyr)",14,"LEU A 273;VAL A 281;ALA A 293;LYS A 295;GLU A 310;MET A 314;VAL A 323;ILE A 336;THR A 338;TYR A 340;MET A 341;GLY A 344;LEU A 393;ASP A 404","DB8 A 601\r"],["4MXO_B_DB8B601","4mxo","DB8","DB06616(Bosutinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","no annotation",13,"LEU B 273;VAL B 281;ALA B 293;LYS B 295;GLU B 310;VAL B 323;ILE B 336;THR B 338;TYR B 340;MET B 341;GLY B 344;LEU B 393;ASP B 404","DB8 B 601\r"],["4MXX_A_DB8A601","4mxx","DB8","DB06616(Bosutinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","PF07714(Pkinase_Tyr)",13,"LEU A 273;ALA A 293;LYS A 295;GLU A 310;MET A 314;VAL A 323;ILE A 336;THR A 338;TYR A 340;MET A 341;GLY A 344;LEU A 393;THR A 403","DB8 A 601\r"],["4MXX_B_DB8B601","4mxx","DB8","DB06616(Bosutinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","no annotation",12,"LEU B 273;VAL B 281;ALA B 293;LYS B 295;VAL B 323;THR B 338;TYR B 340;MET B 341;GLY B 344;LEU B 393;THR B 403;PHE B 405","DB8 B 601\r"],["4MXY_A_DB8A601","4mxy","DB8","DB06616(Bosutinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","PF07714(Pkinase_Tyr)",13,"LEU A 273;VAL A 281;ALA A 293;LYS A 295;GLU A 310;VAL A 323;ILE A 336;MET A 338;TYR A 340;MET A 341;GLY A 344;LEU A 393;ASP A 404","DB8 A 601\r"],["4MXY_B_DB8B601","4mxy","DB8","DB06616(Bosutinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","no annotation",13,"LEU B 273;VAL B 281;ALA B 293;LYS B 295;GLU B 310;VAL B 323;MET B 338;TYR B 340;MET B 341;GLY B 344;LEU B 393;ALA B 403;ASP B 404","DB8 B 601\r"],["4MXZ_A_DB8A601","4mxz","DB8","DB06616(Bosutinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","PF07714(Pkinase_Tyr)",13,"LEU A 273;VAL A 281;ALA A 293;LYS A 295;GLU A 310;VAL A 323;ILE A 336;MET A 338;TYR A 340;MET A 341;GLY A 344;LEU A 393;ASP A 404","DB8 A 601\r"],["4MXZ_B_DB8B601","4mxz","DB8","DB06616(Bosutinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","no annotation",13,"LEU B 273;VAL B 281;ALA B 293;LYS B 295;GLU B 310;VAL B 323;MET B 338;TYR B 340;MET B 341;GLY B 344;LEU B 393;ALA B 403;ASP B 404","DB8 B 601\r"],["4U5J_A_RXTA601","4u5j","RXT","DB08877(Ruxolitinib)","Gallus gallus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","PF07714(Pkinase_Tyr)",11,"LEU A 273;GLY A 276;VAL A 281;ALA A 293;TYR A 340;MET A 341;GLY A 344;ASN A 391;LEU A 393;ALA A 403;ASP A 404","RXT A 601\r"],["4U5J_B_RXTB601","4u5j","RXT","DB08877(Ruxolitinib)","Gallus gallus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","no annotation",9,"LEU B 273;VAL B 281;ALA B 293;LYS B 295;TYR B 340;MET B 341;GLY B 344;LEU B 393;ASP B 404","RXT B 601\r"]]