DRUG BINDING INTERFACES MAPPED TO 'PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1'

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1OPJ_A_STIA3	1opj	STI DB00619 (Imatinib)	Mus musculus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	17	LEU A 267 TYR A 272 VAL A 275 ALA A 288 LYS A 290 GLU A 305 VAL A 308 MET A 309 ILE A 312 VAL A 318 ILE A 332 THR A 334 PHE A 336 MET A 337 LEU A 389 ALA A 399 ASP A 400	STI A 3
1OPJ_B_STIB4	1opj	STI DB00619 (Imatinib)	Mus musculus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	18	LEU B 267 TYR B 272 VAL B 275 ALA B 288 LYS B 290 GLU B 305 VAL B 308 MET B 309 ILE B 312 VAL B 318 ILE B 332 THR B 334 PHE B 336 MET B 337 GLY B 340 ARG B 381 ALA B 399 ASP B 400	STI B 4
2GQG_A_1N1A501	2gqg	1N1 DB01254 (Dasatinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	14	LEU A 248 TYR A 253 ALA A 269 LYS A 271 GLU A 286 MET A 290 VAL A 299 ILE A 313 THR A 315 PHE A 317 MET A 318 GLY A 321 LEU A 370 ALA A 380	1N1 A 501
2GQG_B_1N1B502	2gqg	1N1 DB01254 (Dasatinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	14	LEU B 248 VAL B 256 ALA B 269 LYS B 271 GLU B 286 MET B 290 VAL B 299 ILE B 313 THR B 315 MET B 318 TYR B 320 GLY B 321 LEU B 370 ALA B 380	1N1 B 502
2HYY_A_STIA600	2hyy	STI DB00619 (Imatinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	18	LEU A 248 TYR A 253 VAL A 256 ALA A 269 LYS A 271 GLU A 286 VAL A 289 MET A 290 ILE A 293 VAL A 299 ILE A 313 THR A 315 PHE A 317 GLY A 321 ARG A 362 LEU A 370 ALA A 380 ASP A 381	STI A 600
2HYY_B_STIB600	2hyy	STI DB00619 (Imatinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	18	LEU B 248 TYR B 253 VAL B 256 ALA B 269 LYS B 271 GLU B 286 VAL B 289 MET B 290 ILE B 293 VAL B 299 ILE B 313 THR B 315 PHE B 317 MET B 318 GLY B 321 LEU B 370 ALA B 380 ASP B 381	STI B 600
2HYY_C_STIC600	2hyy	STI DB00619 (Imatinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	18	LEU C 248 TYR C 253 VAL C 256 ALA C 269 LYS C 271 GLU C 286 VAL C 289 MET C 290 ILE C 293 VAL C 299 ILE C 313 THR C 315 PHE C 317 MET C 318 GLY C 321 LEU C 370 ALA C 380 ASP C 381	STI C 600
2HYY_D_STID600	2hyy	STI DB00619 (Imatinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	16	LEU D 248 TYR D 253 VAL D 256 ALA D 269 LYS D 271 GLU D 286 MET D 290 ILE D 293 VAL D 299 ILE D 313 THR D 315 PHE D 317 MET D 318 LEU D 370 ALA D 380 ASP D 381	STI D 600
3CS9_A_NILA600	3cs9	NIL DB04868 (Nilotinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	22	LEU A 248 TYR A 253 VAL A 256 ALA A 269 LYS A 271 LYS A 285 GLU A 286 VAL A 289 MET A 290 ILE A 293 LEU A 298 VAL A 299 ILE A 313 THR A 315 PHE A 317 GLY A 321 PHE A 359 HIS A 361 LEU A 370 VAL A 379 ALA A 380 ASP A 381	NIL A 600
3CS9_B_NILB600	3cs9	NIL DB04868 (Nilotinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	21	LEU B 248 TYR B 253 VAL B 256 ALA B 269 LYS B 271 GLU B 286 VAL B 289 MET B 290 ILE B 293 LEU B 298 VAL B 299 ILE B 313 THR B 315 GLY B 321 PHE B 359 HIS B 361 LEU B 370 VAL B 379 ALA B 380 ASP B 381 PHE B 382	NIL B 600
3CS9_C_NILC600	3cs9	NIL DB04868 (Nilotinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	21	LEU C 248 TYR C 253 VAL C 256 ALA C 269 LYS C 271 GLU C 286 VAL C 289 MET C 290 ILE C 293 LEU C 298 VAL C 299 ILE C 313 THR C 315 PHE C 317 MET C 318 PHE C 359 HIS C 361 VAL C 379 ALA C 380 ASP C 381 PHE C 382	NIL C 600
3CS9_D_NILD600	3cs9	NIL DB04868 (Nilotinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	18	LEU D 248 TYR D 253 VAL D 256 ALA D 269 LYS D 271 GLU D 286 VAL D 289 MET D 290 ILE D 293 LEU D 298 THR D 315 PHE D 317 GLY D 321 PHE D 359 HIS D 361 LEU D 370 ALA D 380 ASP D 381	NIL D 600
3IK3_A_0LIA1	3ik3	0LI DB08901 (Ponatinib)	Mus musculus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	19	LEU A 248 TYR A 253 ALA A 269 LYS A 271 GLU A 286 VAL A 289 MET A 290 ILE A 293 LEU A 298 VAL A 299 ILE A 313 ILE A 315 MET A 318 HIS A 361 ARG A 362 LEU A 370 ALA A 380 ASP A 381 PHE A 382	0LI A 1
3IK3_B_0LIB2	3ik3	0LI DB08901 (Ponatinib)	Mus musculus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	19	LEU B 248 TYR B 253 ALA B 269 LYS B 271 GLU B 286 VAL B 289 MET B 290 ILE B 293 LEU B 298 VAL B 299 ILE B 313 ILE B 315 MET B 318 HIS B 361 ARG B 362 LEU B 370 ALA B 380 ASP B 381 PHE B 382	0LI B 2

[["1OPJ_A_STIA3","1opj","STI","DB00619(Imatinib)","Mus musculus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",17,"LEU A 267;TYR A 272;VAL A 275;ALA A 288;LYS A 290;GLU A 305;VAL A 308;MET A 309;ILE A 312;VAL A 318;ILE A 332;THR A 334;PHE A 336;MET A 337;LEU A 389;ALA A 399;ASP A 400","STI A   3\r"],["1OPJ_B_STIB4","1opj","STI","DB00619(Imatinib)","Mus musculus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",18,"LEU B 267;TYR B 272;VAL B 275;ALA B 288;LYS B 290;GLU B 305;VAL B 308;MET B 309;ILE B 312;VAL B 318;ILE B 332;THR B 334;PHE B 336;MET B 337;GLY B 340;ARG B 381;ALA B 399;ASP B 400","STI B   4\r"],["2GQG_A_1N1A501","2gqg","1N1","DB01254(Dasatinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",14,"LEU A 248;TYR A 253;ALA A 269;LYS A 271;GLU A 286;MET A 290;VAL A 299;ILE A 313;THR A 315;PHE A 317;MET A 318;GLY A 321;LEU A 370;ALA A 380","1N1 A 501\r"],["2GQG_B_1N1B502","2gqg","1N1","DB01254(Dasatinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",14,"LEU B 248;VAL B 256;ALA B 269;LYS B 271;GLU B 286;MET B 290;VAL B 299;ILE B 313;THR B 315;MET B 318;TYR B 320;GLY B 321;LEU B 370;ALA B 380","1N1 B 502\r"],["2HYY_A_STIA600","2hyy","STI","DB00619(Imatinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",18,"LEU A 248;TYR A 253;VAL A 256;ALA A 269;LYS A 271;GLU A 286;VAL A 289;MET A 290;ILE A 293;VAL A 299;ILE A 313;THR A 315;PHE A 317;GLY A 321;ARG A 362;LEU A 370;ALA A 380;ASP A 381","STI A 600\r"],["2HYY_B_STIB600","2hyy","STI","DB00619(Imatinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",18,"LEU B 248;TYR B 253;VAL B 256;ALA B 269;LYS B 271;GLU B 286;VAL B 289;MET B 290;ILE B 293;VAL B 299;ILE B 313;THR B 315;PHE B 317;MET B 318;GLY B 321;LEU B 370;ALA B 380;ASP B 381","STI B 600\r"],["2HYY_C_STIC600","2hyy","STI","DB00619(Imatinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",18,"LEU C 248;TYR C 253;VAL C 256;ALA C 269;LYS C 271;GLU C 286;VAL C 289;MET C 290;ILE C 293;VAL C 299;ILE C 313;THR C 315;PHE C 317;MET C 318;GLY C 321;LEU C 370;ALA C 380;ASP C 381","STI C 600\r"],["2HYY_D_STID600","2hyy","STI","DB00619(Imatinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",16,"LEU D 248;TYR D 253;VAL D 256;ALA D 269;LYS D 271;GLU D 286;MET D 290;ILE D 293;VAL D 299;ILE D 313;THR D 315;PHE D 317;MET D 318;LEU D 370;ALA D 380;ASP D 381","STI D 600\r"],["3CS9_A_NILA600","3cs9","NIL","DB04868(Nilotinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",22,"LEU A 248;TYR A 253;VAL A 256;ALA A 269;LYS A 271;LYS A 285;GLU A 286;VAL A 289;MET A 290;ILE A 293;LEU A 298;VAL A 299;ILE A 313;THR A 315;PHE A 317;GLY A 321;PHE A 359;HIS A 361;LEU A 370;VAL A 379;ALA A 380;ASP A 381","NIL A 600\r"],["3CS9_B_NILB600","3cs9","NIL","DB04868(Nilotinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",21,"LEU B 248;TYR B 253;VAL B 256;ALA B 269;LYS B 271;GLU B 286;VAL B 289;MET B 290;ILE B 293;LEU B 298;VAL B 299;ILE B 313;THR B 315;GLY B 321;PHE B 359;HIS B 361;LEU B 370;VAL B 379;ALA B 380;ASP B 381;PHE B 382","NIL B 600\r"],["3CS9_C_NILC600","3cs9","NIL","DB04868(Nilotinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",21,"LEU C 248;TYR C 253;VAL C 256;ALA C 269;LYS C 271;GLU C 286;VAL C 289;MET C 290;ILE C 293;LEU C 298;VAL C 299;ILE C 313;THR C 315;PHE C 317;MET C 318;PHE C 359;HIS C 361;VAL C 379;ALA C 380;ASP C 381;PHE C 382","NIL C 600\r"],["3CS9_D_NILD600","3cs9","NIL","DB04868(Nilotinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",18,"LEU D 248;TYR D 253;VAL D 256;ALA D 269;LYS D 271;GLU D 286;VAL D 289;MET D 290;ILE D 293;LEU D 298;THR D 315;PHE D 317;GLY D 321;PHE D 359;HIS D 361;LEU D 370;ALA D 380;ASP D 381","NIL D 600\r"],["3IK3_A_0LIA1","3ik3","0LI","DB08901(Ponatinib)","Mus musculus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",19,"LEU A 248;TYR A 253;ALA A 269;LYS A 271;GLU A 286;VAL A 289;MET A 290;ILE A 293;LEU A 298;VAL A 299;ILE A 313;ILE A 315;MET A 318;HIS A 361;ARG A 362;LEU A 370;ALA A 380;ASP A 381;PHE A 382","0LI A   1\r"],["3IK3_B_0LIB2","3ik3","0LI","DB08901(Ponatinib)","Mus musculus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",19,"LEU B 248;TYR B 253;ALA B 269;LYS B 271;GLU B 286;VAL B 289;MET B 290;ILE B 293;LEU B 298;VAL B 299;ILE B 313;ILE B 315;MET B 318;HIS B 361;ARG B 362;LEU B 370;ALA B 380;ASP B 381;PHE B 382","0LI B   2\r"]]