DRUG BINDING INTERFACES MAPPED TO 'PROSTAGLANDIN G/H SYNTHASE 1'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 2AYL_A_FLPA1701 | 2ayl | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 14 | VAL A 116ARG A 120VAL A 349LEU A 352TYR A 355LEU A 359TYR A 385TRP A 387PHE A 518ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | FLP A1701 |
| 2AYL_B_FLPB2701 | 2ayl | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 13 | VAL B1116ARG B1120VAL B1349LEU B1352TYR B1355LEU B1359TYR B1385TRP B1387ILE B1523GLY B1526ALA B1527SER B1530LEU B1531 | FLP B2701 |
| 3KK6_A_CELA701 | 3kk6 | CEL DB00482(Celecoxib) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 18 | HIS A 90VAL A 116GLN A 192VAL A 349LEU A 352SER A 353TYR A 355LEU A 359LEU A 384TRP A 387SER A 516ILE A 517PHE A 518ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | CEL A 701 |
| 3KK6_B_CELB1701 | 3kk6 | CEL DB00482(Celecoxib) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 18 | HIS B 90VAL B 116GLN B 192VAL B 349LEU B 352SER B 353TYR B 355LEU B 359LEU B 384TRP B 387SER B 516ILE B 517PHE B 518ILE B 523GLY B 526ALA B 527SER B 530LEU B 531 | CEL B1701 |
| 3N8W_A_FLPA701 | 3n8w | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 12 | VAL A 116ARG A 120VAL A 349LEU A 352TYR A 355LEU A 359TYR A 385TRP A 387GLY A 526ALA A 527SER A 530LEU A 531 | FLP A 701 |
| 3N8X_A_NIMA701 | 3n8x | NIM DB04743(Nimesulide) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 15 | HIS A 90ARG A 120VAL A 349LEU A 352SER A 353TYR A 355LEU A 359TYR A 385TRP A 387PHE A 518ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | NIM A 701 |
| 3N8X_B_NIMB1701 | 3n8x | NIM DB04743(Nimesulide) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 15 | HIS B 90VAL B 116ARG B 120VAL B 349LEU B 352SER B 353TYR B 355LEU B 359TRP B 387PHE B 518ILE B 523GLY B 526ALA B 527SER B 530LEU B 531 | NIM B1701 |
| 3N8Y_A_DIFA701 | 3n8y | DIF DB00586(Diclofenac) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 11 | VAL A 349LEU A 352SER A 353TYR A 355TYR A 385TRP A 387ILE A 523GLY A 526ALA A 527SER A 530LEU A 531 | DIF A 701 |
| 3N8Y_B_DIFB585 | 3n8y | DIF DB00586(Diclofenac) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 12 | VAL B 344VAL B 349LEU B 352SER B 353TYR B 355TYR B 385TRP B 387ILE B 523GLY B 526ALA B 527LEU B 531LEU B 534 | DIF B 585 |
| 3N8Y_B_SALB900 | 3n8y | SAL DB00936(Salicylicacid) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 5 | VAL B 349LEU B 352TYR B 355ILE B 523ALA B 527 | SAL B 900 |
| 3N8Z_A_FLPA701 | 3n8z | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 12 | VAL A 116ARG A 120VAL A 349LEU A 352TYR A 355LEU A 359TYR A 385TRP A 387GLY A 526ALA A 527SER A 530LEU A 531 | FLP A 701 |
| 3N8Z_B_FLPB1701 | 3n8z | FLP DB00712(Flurbiprofen) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 13 | VAL B 116ARG B 120VAL B 349LEU B 352TYR B 355LEU B 384TYR B 385TRP B 387ILE B 523GLY B 526ALA B 527SER B 530LEU B 531 | FLP B1701 |
| 4O1Z_A_MXMA807 | 4o1z | MXM DB00814(Meloxicam) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | PF00008(EGF)PF03098(An_peroxidase) | 18 | MET A 113VAL A 116LEU A 117ARG A 120ILE A 345VAL A 349LEU A 352LEU A 359TRP A 387PHE A 518MET A 522ILE A 523GLY A 526ALA A 527SER A 530LEU A 531LEU A 534LEU A 535 | MXM A 807 |
| 4O1Z_B_MXMB807 | 4o1z | MXM DB00814(Meloxicam) | Ovis aries | PROSTAGLANDIN G/HSYNTHASE 1 | no annotation | 13 | MET B 113VAL B 116LEU B 117ARG B 120ILE B 345VAL B 349LEU B 359TRP B 387PHE B 518MET B 522ALA B 527SER B 530LEU B 531 | MXM B 807 |