DRUG BINDING INTERFACES MAPPED TO 'PROLYL-TRNA SYNTHETASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 5XIP_A_HFGA1003 | 5xip | HFG DB04866(Halofuginone) | Eimeria tenella | PROLYL-TRNASYNTHETASE, PUTATIVE | PF00587(ProRS-C_1)PF03129(tRNA-synt_2b)PF09180(HGTP_anticodon) | 15 | LEU A 325PHE A 335GLU A 338VAL A 339PRO A 358THR A 359GLU A 361ARG A 390TRP A 407HIS A 411PHE A 454THR A 478HIS A 480SER A 508GLY A 510 | HFG A1003 |
| 5XIP_B_HFGB1003 | 5xip | HFG DB04866(Halofuginone) | Eimeria tenella | PROLYL-TRNASYNTHETASE, PUTATIVE | None | 12 | PHE B 335GLU B 338VAL B 339PRO B 358THR B 359GLU B 361ARG B 390TRP B 407HIS B 411PHE B 454THR B 478HIS B 480 | HFG B1003 |
| 5XIP_C_HFGC1003 | 5xip | HFG DB04866(Halofuginone) | Eimeria tenella | PROLYL-TRNASYNTHETASE, PUTATIVE | None | 14 | LEU C 325GLU C 338VAL C 339PRO C 358THR C 359GLU C 361ARG C 390TRP C 407GLU C 409HIS C 411PHE C 454THR C 478HIS C 480GLY C 510 | HFG C1003 |
| 5XIP_D_HFGD1003 | 5xip | HFG DB04866(Halofuginone) | Eimeria tenella | PROLYL-TRNASYNTHETASE, PUTATIVE | None | 13 | LEU D 325GLU D 338VAL D 339PRO D 358THR D 359GLU D 361ARG D 390TRP D 407GLU D 409PHE D 454THR D 478HIS D 480TRP D 509 | HFG D1003 |
| 5XIQ_A_HFGA1002 | 5xiq | HFG DB04866(Halofuginone) | Toxoplasma gondii | PROLYL-TRNASYNTHETASE (PRORS) | PF00587(HGTP_anticodon)PF03129(ProRS-C_1)PF09180(tRNA-synt_2b) | 16 | LEU A 405PHE A 415GLU A 418VAL A 419PRO A 438THR A 439GLU A 441ARG A 470TRP A 487GLU A 489HIS A 491PHE A 534THR A 558HIS A 560SER A 588GLY A 590 | HFG A1002 |
| 5XIQ_B_HFGB1002 | 5xiq | HFG DB04866(Halofuginone) | Toxoplasma gondii | PROLYL-TRNASYNTHETASE (PRORS) | None | 15 | LEU B 405PHE B 415GLU B 418VAL B 419PRO B 438THR B 439GLU B 441ARG B 470TRP B 487GLU B 489HIS B 491PHE B 534THR B 558HIS B 560SER B 588 | HFG B1002 |
| 5XIQ_C_HFGC1002 | 5xiq | HFG DB04866(Halofuginone) | Toxoplasma gondii | PROLYL-TRNASYNTHETASE (PRORS) | None | 14 | PHE C 415GLU C 418VAL C 419PRO C 438THR C 439GLU C 441ARG C 470TRP C 487GLU C 489HIS C 491PHE C 534THR C 558HIS C 560SER C 588 | HFG C1002 |
| 5XIQ_D_HFGD1002 | 5xiq | HFG DB04866(Halofuginone) | Toxoplasma gondii | PROLYL-TRNASYNTHETASE (PRORS) | None | 15 | LEU D 405PHE D 415GLU D 418VAL D 419PRO D 438THR D 439GLU D 441ARG D 470TRP D 487GLU D 489HIS D 491PHE D 534THR D 558HIS D 560GLY D 590 | HFG D1002 |