DRUG BINDING INTERFACES MAPPED TO 'PORIN'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1UOB_A_PNNA1311 | 1uob | PNN DB01053(Benzylpenicillin) | Streptomycesclavuligerus | DEACETOXYCEPHALOSPORIN C SYNTHETASE | PF03171(DIOX_N)PF14226(2OG-FeII_Oxy) | 15 | MET A 73SER A 102LEU A 158ARG A 160ARG A 162MET A 180HIS A 183ASP A 185ILE A 192LEU A 204HIS A 243SER A 260VAL A 262PHE A 264ILE A 305 | PNN A1311 |
1UOF_A_PNNA1312 | 1uof | PNN DB01053(Benzylpenicillin) | Streptomycesclavuligerus | DEACETOXYCEPHALOSPORIN C SYNTHETASE | PF03171(2OG-FeII_Oxy)PF14226(DIOX_N) | 11 | PHE A 164ARG A 179MET A 180HIS A 183ASP A 185THR A 190HIS A 243VAL A 245ARG A 258SER A 260VAL A 262 | PNN A1312 |
2BM9_A_SAMA301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | PF04989(CmcI) | 15 | LEU A 18LEU A 64LYS A 65GLU A 87GLY A 89TYR A 91SER A 95ASP A 116ARG A 117ARG A 121ASP A 138CYS A 139ASN A 160ALA A 161ALA A 163 | SAM A 301 |
2BM9_B_SAMB301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 13 | LEU B 18LEU B 64LYS B 65GLU B 87GLY B 89SER B 95ASP B 116ARG B 117ARG B 121ASP B 138CYS B 139ASN B 160ALA B 163 | SAM B 301 |
2BM9_C_SAMC301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 16 | LEU C 18LEU C 64LYS C 65GLU C 87GLY C 89TYR C 91ASN C 92SER C 95ASP C 116ARG C 117ARG C 121ASP C 138CYS C 139ASN C 160ALA C 161ALA C 163 | SAM C 301 |
2BM9_D_SAMD301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 15 | LEU D 18LEU D 64LYS D 65GLU D 87GLY D 89TYR D 91SER D 95ASP D 116ARG D 117ARG D 121ASP D 138CYS D 139ASN D 160ALA D 161ALA D 163 | SAM D 301 |
2BM9_E_SAME301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 14 | LEU E 18LEU E 64LYS E 65GLU E 87GLY E 89SER E 95ASP E 116ARG E 117ARG E 121ASP E 138CYS E 139ASN E 160ALA E 161ALA E 163 | SAM E 301 |
2BM9_F_SAMF301 | 2bm9 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 13 | GLY F 17LEU F 18LEU F 64GLY F 89ASP F 116ARG F 117ARG F 121CYS F 139ASN F 160ALA F 161HIS F 162ALA F 163ASP F 187 | SAM F 301 |
2BR4_A_SAMA301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | PF04989(CmcI) | 15 | LEU A 18LEU A 64LYS A 65GLU A 87GLY A 89TYR A 91SER A 95ASP A 116ARG A 117ARG A 121ASP A 138CYS A 139ASP A 160ALA A 161ALA A 163 | SAM A 301 |
2BR4_B_SAMB301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 16 | LEU B 18LEU B 64LYS B 65GLU B 87GLY B 89TYR B 91ASN B 92SER B 95ASP B 116ARG B 117ARG B 121ASP B 138CYS B 139ASP B 160ALA B 161ALA B 163 | SAM B 301 |
2BR4_C_SAMC301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 16 | LEU C 18LEU C 64LYS C 65GLU C 87GLY C 89TYR C 91SER C 95ASP C 116ARG C 117ARG C 121ASP C 138CYS C 139SER C 140ASP C 160ALA C 161ALA C 163 | SAM C 301 |
2BR4_D_SAMD301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 15 | LEU D 18LEU D 64LYS D 65GLU D 87GLY D 89TYR D 91SER D 95ASP D 116ARG D 117ARG D 121ASP D 138CYS D 139ASP D 160ALA D 161ALA D 163 | SAM D 301 |
2BR4_E_SAME301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 15 | LEU E 18LEU E 64LYS E 65GLU E 87GLY E 89TYR E 91SER E 95ASP E 116ARG E 117ARG E 121ASP E 138CYS E 139ASP E 160ALA E 161ALA E 163 | SAM E 301 |
2BR4_F_SAMF301 | 2br4 | SAM DB00118(S-Adenosylmethionine) | Streptomycesclavuligerus | CEPHALOSPORINHYDROXYLASE CMCI | None | 15 | LEU F 18LEU F 64LYS F 65GLU F 87GLY F 89TYR F 91SER F 95ASP F 116ARG F 117ARG F 121ASP F 138CYS F 139ASP F 160ALA F 161ALA F 163 | SAM F 301 |
2VAV_A_CSCA1383 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | PF00561(Abhydrolase_1) | 11 | THR A 58LEU A 59THR A 60ARG A 218TYR A 225LYS A 226ARG A 234HIS A 362ASP A 363PHE A 365MET A 367 | CSC A1383 |
2VAV_B_CSCB1384 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 13 | THR B 58LEU B 59THR B 60ARG B 218TYR B 225LYS B 226ARG B 234GLN B 281HIS B 362ASP B 363PHE B 365VAL B 366MET B 367 | CSC B1384 |
2VAV_C_CSCC1383 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR C 58LEU C 59THR C 60ARG C 218TYR C 225LYS C 226ARG C 234TYR C 277GLN C 281HIS C 362ASP C 363PHE C 365VAL C 366MET C 367 | CSC C1383 |
2VAV_D_CSCD1383 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR D 58LEU D 59THR D 60ARG D 218TYR D 225LYS D 226ARG D 234TYR D 277GLN D 281HIS D 362ASP D 363PHE D 365VAL D 366MET D 367 | CSC D1383 |
2VAV_E_CSCE1383 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 13 | THR E 58LEU E 59THR E 60ARG E 218TYR E 225LYS E 226ARG E 234TYR E 277GLN E 281HIS E 362ASP E 363PHE E 365MET E 367 | CSC E1383 |
2VAV_F_CSCF1383 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 15 | THR F 58LEU F 59THR F 60MET F 150ARG F 218TYR F 225LYS F 226ARG F 234TYR F 277GLN F 281PHE F 301ASP F 363PHE F 365VAL F 366MET F 367 | CSC F1383 |
2VAV_G_CSCG1383 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR G 58LEU G 59THR G 60ARG G 218TYR G 225LYS G 226ARG G 234TYR G 277GLN G 281HIS G 362ASP G 363PHE G 365VAL G 366MET G 367 | CSC G1383 |
2VAV_H_CSCH1383 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR H 58LEU H 59THR H 60MET H 150ARG H 218TYR H 225LYS H 226ARG H 234TYR H 277PHE H 301HIS H 362ASP H 363VAL H 366MET H 367 | CSC H1383 |
2VAV_I_CSCI1383 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 13 | THR I 58LEU I 59THR I 60ARG I 218TYR I 225LYS I 226ARG I 234GLN I 281HIS I 362ASP I 363PHE I 365VAL I 366MET I 367 | CSC I1383 |
2VAV_J_CSCJ1385 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 12 | THR J 58LEU J 59THR J 60ARG J 218TYR J 225LYS J 226ARG J 234TYR J 277GLN J 281ASP J 363PHE J 365VAL J 366 | CSC J1385 |
2VAV_K_CSCK1385 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 13 | THR K 58LEU K 59THR K 60ARG K 218TYR K 225LYS K 226ARG K 234TYR K 277GLN K 281ASP K 363PHE K 365VAL K 366MET K 367 | CSC K1385 |
2VAV_L_CSCL1383 | 2vav | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 16 | THR L 58LEU L 59THR L 60MET L 150ARG L 218TYR L 225LYS L 226ARG L 234TYR L 277GLN L 281PHE L 301HIS L 362ASP L 363PHE L 365VAL L 366MET L 367 | CSC L1383 |
2VAX_A_CSCA1383 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | PF00561(Abhydrolase_1) | 13 | THR A 58LEU A 59THR A 60ARG A 218TYR A 225LYS A 226ARG A 234TYR A 277GLN A 281HIS A 362ASP A 363PHE A 365MET A 367 | CSC A1383 |
2VAX_B_CSCB1384 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 13 | THR B 58LEU B 59THR B 60ARG B 218ASN B 222TYR B 225LYS B 226TYR B 277GLN B 281HIS B 362ASP B 363PHE B 365VAL B 366 | CSC B1384 |
2VAX_C_CSCC1383 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR C 58LEU C 59THR C 60ARG C 218TYR C 225LYS C 226ARG C 234TYR C 277GLN C 281HIS C 362ASP C 363PHE C 365VAL C 366MET C 367 | CSC C1383 |
2VAX_D_CSCD1383 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR D 58LEU D 59THR D 60ARG D 218TYR D 225LYS D 226ARG D 234TYR D 277GLN D 281HIS D 362ASP D 363PHE D 365VAL D 366MET D 367 | CSC D1383 |
2VAX_E_CSCE1383 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 13 | THR E 58LEU E 59THR E 60ARG E 218TYR E 225LYS E 226ARG E 234TYR E 277GLN E 281HIS E 362ASP E 363PHE E 365MET E 367 | CSC E1383 |
2VAX_F_CSCF1384 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR F 58LEU F 59THR F 60ARG F 218TYR F 225LYS F 226ARG F 234TYR F 277GLN F 281HIS F 362ASP F 363PHE F 365VAL F 366MET F 367 | CSC F1384 |
2VAX_G_CSCG1383 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 13 | THR G 58LEU G 59THR G 60ARG G 218TYR G 225LYS G 226ARG G 234GLN G 281HIS G 362ASP G 363PHE G 365VAL G 366MET G 367 | CSC G1383 |
2VAX_H_CSCH1383 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR H 58LEU H 59THR H 60TRP H 68ARG H 218TYR H 225LYS H 226ARG H 234TYR H 277GLN H 281HIS H 362ASP H 363PHE H 365VAL H 366 | CSC H1383 |
2VAX_I_CSCI1384 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 13 | THR I 58LEU I 59THR I 60ARG I 218ASN I 222TYR I 225LYS I 226TYR I 277GLN I 281HIS I 362ASP I 363PHE I 365VAL I 366 | CSC I1384 |
2VAX_J_CSCJ1385 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 13 | THR J 58LEU J 59THR J 60ARG J 218TYR J 225LYS J 226ARG J 234TYR J 277GLN J 281HIS J 362ASP J 363PHE J 365MET J 367 | CSC J1385 |
2VAX_K_CSCK1385 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR K 58LEU K 59THR K 60TRP K 68ARG K 218TYR K 225LYS K 226ARG K 234TYR K 277GLN K 281HIS K 362ASP K 363PHE K 365VAL K 366 | CSC K1385 |
2VAX_L_CSCL1383 | 2vax | CSC DB03313(CephalosporinC) | Acremoniumchrysogenum | ACETYL-COA--DEACETYLCEPHALOSPORIN CACETYLTRANSFERASE | no annotation | 14 | THR L 58LEU L 59THR L 60ARG L 218TYR L 225LYS L 226ARG L 234TYR L 277GLN L 281HIS L 362ASP L 363PHE L 365VAL L 366MET L 367 | CSC L1383 |