DRUG BINDING INTERFACES MAPPED TO 'POLY [ADP-RIBOSE] POLYMERASE 1'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
4RV6_A_RPBA1103 4rv6 RPB

DB12332
(Rucaparib) 		Homo sapiens POLY [ADP-RIBOSE]
POLYMERASE 1 		PF00644
(PARP)
PF02877
(PARP_reg) 		11 GLN A 759
GLU A 763
HIS A 862
GLY A 863
TYR A 889
TYR A 896
ALA A 898
LYS A 903
SER A 904
TYR A 907
GLU A 988
 RPB A1103
4RV6_B_RPBB1103 4rv6 RPB

DB12332
(Rucaparib) 		Homo sapiens POLY [ADP-RIBOSE]
POLYMERASE 1 		no annotation 11 GLN B 759
GLU B 763
HIS B 862
GLY B 863
TYR B 889
TYR B 896
ALA B 898
LYS B 903
SER B 904
TYR B 907
GLU B 988
 RPB B1103
5HA9_B_TP0B406 5ha9 TP0

DB00321
(Amitriptyline) 		Homo sapiens POLY [ADP-RIBOSE]
POLYMERASE 1 		no annotation 9 GLU B 102
ASP B 109
HIS B 201
SER B 203
ASN B 207
ILE B 211
TYR B 235
SER B 243
TYR B 246
 TP0 B 406