DRUG BINDING INTERFACES MAPPED TO 'PLASMINOGEN ACTIVATOR'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
1F5L_A_AMRA301
1f5l
AMR
DB00594(Amiloride)
Homo sapiens
UROKINASE-TYPEPLASMINOGENACTIVATOR
PF00089(Trypsin)
8
ASP A 189SER A 190GLN A 192SER A 195VAL A 213GLY A 216CYS A 220GLY A 226
AMR A 301
1PK2_A_ACAA91
1pk2
ACA
DB00513(AminocaproicAcid)
Homo sapiens
TISSUE-TYPEPLASMINOGENACTIVATOR
PF00051(Kringle)
8
VAL A 40TYR A 41ASP A 63ASP A 65TRP A 69HIS A 71LEU A 78TRP A 80
ACA A 91
2VIN_A_505A1247
2vin
505
DB00379(Mexiletine)
Homo sapiens
UROKINASE-TYPEPLASMINOGENACTIVATOR CHAIN B
PF00089(Trypsin)
8
ASP A 189SER A 190GLN A 192SER A 195VAL A 213GLY A 216CYS A 220GLY A 226
505 A1247
4FU8_A_ACTA302
4fu8
ACT
DB03166(Aceticacid)
Homo sapiens
UROKINASE-TYPEPLASMINOGENACTIVATOR
PF00089(Trypsin)
5
HIS A 46TYR A 150GLN A 195GLY A 196SER A 198
ACT A 302
4FU8_A_ACTA304
4fu8
ACT
DB03166(Aceticacid)
Homo sapiens
UROKINASE-TYPEPLASMINOGENACTIVATOR
PF00089(Trypsin)
3
ARG A 20HIS A 22TYR A 51
ACT A 304
4FU9_A_ACTA311
4fu9
ACT
DB03166(Aceticacid)
Homo sapiens
UROKINASE-TYPEPLASMINOGENACTIVATOR
PF00089(Trypsin)
3
GLN A 168THR A 178THR A 179
ACT A 311
4FU9_A_ACTA312
4fu9
ACT
DB03166(Aceticacid)
Homo sapiens
UROKINASE-TYPEPLASMINOGENACTIVATOR
PF00089(Trypsin)
3
ARG A 20HIS A 22TYR A 51
ACT A 312
4FUB_A_ACTA311
4fub
ACT
DB03166(Aceticacid)
Homo sapiens
UROKINASE-TYPEPLASMINOGENACTIVATOR
PF00089(Trypsin)
3
TYR A 126ARG A 233HIS A 236
ACT A 311
4FUF_A_ACTA310
4fuf
ACT
DB03166(Aceticacid)
Homo sapiens
UROKINASE-TYPEPLASMINOGENACTIVATOR
PF00089(Trypsin)
3
GLN A 168THR A 178THR A 179
ACT A 310
[["1F5L_A_AMRA301","1f5l","AMR","DB00594(Amiloride)","Homo sapiens","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","PF00089(Trypsin)",8,"ASP A 189;SER A 190;GLN A 192;SER A 195;VAL A 213;GLY A 216;CYS A 220;GLY A 226","AMR A 301\r"],["1PK2_A_ACAA91","1pk2","ACA","DB00513(Aminocaproic Acid)","Homo sapiens","TISSUE-TYPE PLASMINOGEN ACTIVATOR","PF00051(Kringle)",8,"VAL A 40;TYR A 41;ASP A 63;ASP A 65;TRP A 69;HIS A 71;LEU A 78;TRP A 80","ACA A 91\r"],["2VIN_A_505A1247","2vin","505","DB00379(Mexiletine)","Homo sapiens","UROKINASE-TYPE PLASMINOGEN ACTIVATOR CHAIN B","PF00089(Trypsin)",8,"ASP A 189;SER A 190;GLN A 192;SER A 195;VAL A 213;GLY A 216;CYS A 220;GLY A 226","505 A1247\r"],["4FU8_A_ACTA302","4fu8","ACT","DB03166(Acetic acid)","Homo sapiens","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","PF00089(Trypsin)",5,"HIS A 46;TYR A 150;GLN A 195;GLY A 196;SER A 198","ACT A 302\r"],["4FU8_A_ACTA304","4fu8","ACT","DB03166(Acetic acid)","Homo sapiens","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","PF00089(Trypsin)",3,"ARG A 20;HIS A 22;TYR A 51","ACT A 304\r"],["4FU9_A_ACTA311","4fu9","ACT","DB03166(Acetic acid)","Homo sapiens","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","PF00089(Trypsin)",3,"GLN A 168;THR A 178;THR A 179","ACT A 311\r"],["4FU9_A_ACTA312","4fu9","ACT","DB03166(Acetic acid)","Homo sapiens","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","PF00089(Trypsin)",3,"ARG A 20;HIS A 22;TYR A 51","ACT A 312\r"],["4FUB_A_ACTA311","4fub","ACT","DB03166(Acetic acid)","Homo sapiens","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","PF00089(Trypsin)",3,"TYR A 126;ARG A 233;HIS A 236","ACT A 311\r"],["4FUF_A_ACTA310","4fuf","ACT","DB03166(Acetic acid)","Homo sapiens","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","PF00089(Trypsin)",3,"GLN A 168;THR A 178;THR A 179","ACT A 310\r"]]