DRUG BINDING INTERFACES MAPPED TO 'PHOSPHOHYDROLASE'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
4S2V_A_ACTA229 4s2v ACT

DB03166
(Acetic
acid)
Escherichia coli RNA
PYROPHOSPHOHYDROLASE
PF00293
(NUDIX)
3 TRP A 131
LYS A 150
ALA A 153
ACT A 229
6DWD_A_GLYA715 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None
PF01966
(HD)
6 GLY A 357
ASN A 358
ASP A 361
SER C 368
ARG C 371
ARG C 372
GLY A 715
6DWD_A_GLYA717 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
PF01966
(HD)
5 SER A 192
ARG A 194
ASP A 195
ARG A 290
LYS A 294
GLY A 717
6DWD_B_GLYB709 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None 5 GLY B 357
ASN B 358
ASP B 361
ARG D 371
ARG D 372
GLY B 709
6DWD_C_GLYC713 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None 3 GLN C 447
TYR C 450
ASN C 452
GLY C 713
6DWD_D_GLYD713 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None 3 ARG D 305
HIS D 517
ARG D 531
GLY D 713
6DWJ_B_GLYB710 6dwj GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None 5 GLY D 357
ASN D 358
ASP D 361
ARG B 371
ARG B 372
GLY B 710