DRUG BINDING INTERFACES MAPPED TO 'NUCLEOSIDE PHOSPHORYLASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1ODI_A_ADNA1237 | 1odi | ADN DB00640(Adenosine) | Thermusthermophilus | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 13 | HIS B 5ARG B 44MET A 65ARG A 87THR A 90GLY A 92GLU A 156GLU A 179MET A 180GLU A 181SER A 203ASN A 204ILE A 206 | ADN A1237 |
1ODI_B_ADNB1237 | 1odi | ADN DB00640(Adenosine) | Thermusthermophilus | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 13 | HIS A 5ARG A 44MET B 65ARG B 87THR B 90GLY B 92GLU B 156GLU B 179MET B 180GLU B 181SER B 203ASN B 204ILE B 206 | ADN B1237 |
1ODI_C_ADNC1238 | 1odi | ADN DB00640(Adenosine) | Thermusthermophilus | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 13 | HIS D 5ARG D 44MET C 65ARG C 87THR C 90GLY C 92GLU C 156GLU C 179MET C 180GLU C 181SER C 203ASN C 204ILE C 206 | ADN C1238 |
1ODI_D_ADND1237 | 1odi | ADN DB00640(Adenosine) | Thermusthermophilus | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 13 | HIS C 5ARG C 44MET D 65ARG D 87THR D 90GLY D 92GLU D 156GLU D 179MET D 180GLU D 181SER D 203ASN D 204ILE D 206 | ADN D1237 |
1ODI_E_ADNE1237 | 1odi | ADN DB00640(Adenosine) | Thermusthermophilus | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 13 | HIS F 5ARG F 44MET E 65ARG E 87THR E 90GLY E 92GLU E 156GLU E 179MET E 180GLU E 181SER E 203ASN E 204ILE E 206 | ADN E1237 |
1ODI_F_ADNF1238 | 1odi | ADN DB00640(Adenosine) | Thermusthermophilus | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 13 | HIS E 5ARG E 44MET F 65ARG F 87THR F 90GLY F 92GLU F 156GLU F 179MET F 180GLU F 181SER F 203ASN F 204ILE F 206 | ADN F1238 |
1PK7_A_ADNA1245 | 1pk7 | ADN DB00640(Adenosine) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 9 | MET A 64ARG A 87SER A 90GLY A 92GLU A 179MET A 180GLU A 181SER A 203ASP A 204 | ADN A1245 |
1PK7_B_ADNB1246 | 1pk7 | ADN DB00640(Adenosine) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 8 | ARG B 87GLY B 92VAL B 178GLU B 179MET B 180GLU B 181SER B 203ILE B 206 | ADN B1246 |
1PK7_C_ADNC1247 | 1pk7 | ADN DB00640(Adenosine) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 10 | MET C 64ARG C 87SER C 90GLY C 92VAL C 178GLU C 179MET C 180GLU C 181SER C 203ASP C 204 | ADN C1247 |
1PK9_A_2FAA306 | 1pk9 | 2FA DB01073(Fludarabine) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 10 | MET A 64ARG A 87SER A 90GLY A 92VAL A 178GLU A 179MET A 180GLU A 181SER A 203ASP A 204 | 2FA A 306 |
1PK9_B_2FAB307 | 1pk9 | 2FA DB01073(Fludarabine) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 9 | MET B 64ARG B 87SER B 90GLY B 92GLU B 179MET B 180GLU B 181SER B 203ASP B 204 | 2FA B 307 |
1PK9_C_2FAC308 | 1pk9 | 2FA DB01073(Fludarabine) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 11 | MET C 64ARG C 87SER C 90GLY C 92VAL C 178GLU C 179MET C 180GLU C 181SER C 203ASP C 204ILE C 206 | 2FA C 308 |
1PW7_A_RABA645 | 1pw7 | RAB DB00194(Vidarabine) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 10 | MET A 64ARG A 87SER A 90GLY A 92GLU A 179MET A 180GLU A 181SER A 203ASP A 204ILE A 206 | RAB A 645 |
1PW7_B_RABB646 | 1pw7 | RAB DB00194(Vidarabine) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 9 | MET B 64ARG B 87SER B 90GLY B 92VAL B 178GLU B 179MET B 180GLU B 181ILE B 206 | RAB B 646 |
1PW7_C_RABC647 | 1pw7 | RAB DB00194(Vidarabine) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 9 | MET C 64SER C 90VAL C 178GLU C 179MET C 180GLU C 181SER C 203ASP C 204ILE C 206 | RAB C 647 |
1PWY_E_AC2E290 | 1pwy | AC2 DB00787(Aciclovir) | Homo sapiens | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 10 | GLY E 118PHE E 200GLU E 201VAL E 217GLY E 218MET E 219THR E 242ASN E 243VAL E 245HIS E 257 | AC2 E 290 |
1V3Q_E_2DIE290 | 1v3q | 2DI DB00900(Didanosine) | Homo sapiens | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 10 | GLY E 118PHE E 200GLU E 201VAL E 217GLY E 218MET E 219THR E 242ASN E 243VAL E 245HIS E 257 | 2DI E 290 |
1VHW_A_ADNA252 | 1vhw | ADN DB00640(Adenosine) | Vibrio cholerae | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 11 | HIS D 5ARG D 44MET A 65ARG A 88SER A 91GLY A 93VAL A 179GLU A 180MET A 181GLU A 182ILE A 207 | ADN A 252 |
1VHW_B_ADNB252 | 1vhw | ADN DB00640(Adenosine) | Vibrio cholerae | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 9 | HIS F 5ARG F 44MET B 65ARG B 88SER B 91GLY B 93VAL B 179MET B 181GLU B 182 | ADN B 252 |
1VHW_C_ADNC252 | 1vhw | ADN DB00640(Adenosine) | Vibrio cholerae | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 11 | HIS E 5ARG E 44MET C 65ARG C 88SER C 91GLY C 93VAL C 179GLU C 180MET C 181GLU C 182ILE C 207 | ADN C 252 |
1VHW_D_ADND252 | 1vhw | ADN DB00640(Adenosine) | Vibrio cholerae | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 11 | HIS A 5ARG A 44MET D 65ARG D 88SER D 91GLY D 93VAL D 179GLU D 180MET D 181GLU D 182ILE D 207 | ADN D 252 |
1VHW_E_ADNE252 | 1vhw | ADN DB00640(Adenosine) | Vibrio cholerae | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 11 | HIS C 5ARG C 44MET E 65ARG E 88SER E 91GLY E 93VAL E 179GLU E 180MET E 181GLU E 182ILE E 207 | ADN E 252 |
1VHW_F_ADNF252 | 1vhw | ADN DB00640(Adenosine) | Vibrio cholerae | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 10 | HIS B 5ARG B 44MET F 65ARG F 88SER F 91GLY F 93VAL F 179GLU F 180MET F 181GLU F 182 | ADN F 252 |
1Z35_A_2FAA300 | 1z35 | 2FA DB01073(Fludarabine) | Trichomonasvaginalis | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 10 | MET A 64ARG A 87THR A 90GLY A 92THR A 156VAL A 178GLU A 179MET A 180GLU A 181SER A 203 | 2FA A 300 |
1Z37_A_ADNA300 | 1z37 | ADN DB00640(Adenosine) | Trichomonasvaginalis | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 9 | MET A 64ARG A 87THR A 90GLY A 92VAL A 178GLU A 179MET A 180GLU A 181SER A 203 | ADN A 300 |
2AC7_A_ADNA1216 | 2ac7 | ADN DB00640(Adenosine) | Bacillus cereus | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 11 | HIS B 4ARG B 43MET A 64ARG A 87THR A 90GLY A 92VAL A 178GLU A 179MET A 180GLU A 181ASP A 204 | ADN A1216 |
2AC7_B_ADNB1215 | 2ac7 | ADN DB00640(Adenosine) | Bacillus cereus | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 11 | HIS A 4ARG A 43MET B 64ARG B 87THR B 90GLY B 92VAL B 178GLU B 179MET B 180GLU B 181ASP B 204 | ADN B1215 |
3E9R_A_ACTA700 | 3e9r | ACT DB03166(Aceticacid) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 6 | GLY A 120TYR A 202GLU A 203GLY A 220MET A 221ASN A 245 | ACT A 700 |
3E9R_C_ACTC700 | 3e9r | ACT DB03166(Aceticacid) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | None | 6 | GLY C 120TYR C 202GLU C 203GLY C 220MET C 221ASN C 245 | ACT C 700 |
3F8W_A_ADNA300 | 3f8w | ADN DB00640(Adenosine) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 14 | SER A 35TYR A 90ALA A 118GLY A 120PHE B 161TYR A 202GLU A 203VAL A 219GLY A 220MET A 221THR A 244ASN A 245HIS A 259VAL A 262 | ADN A 300 |
3F8W_B_ADNB301 | 3f8w | ADN DB00640(Adenosine) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | no annotation | 13 | SER B 35HIS B 88TYR B 90GLY B 120TYR B 202GLU B 203VAL B 219GLY B 220MET B 221THR B 244ASN B 245HIS B 259VAL B 262 | ADN B 301 |
3F8W_C_ADNC302 | 3f8w | ADN DB00640(Adenosine) | Schistosomamansoni | PURINE-NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 15 | SER C 35HIS C 88TYR C 90ALA C 118GLY C 120PHE A 161TYR C 202GLU C 203VAL C 219GLY C 220MET C 221THR C 244ASN C 245HIS C 259VAL C 262 | ADN C 302 |
3U40_A_ADNA251 | 3u40 | ADN DB00640(Adenosine) | Entamoebahistolytica | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 9 | HIS F 9ARG F 48MET A 69ARG A 92SER A 95VAL A 182GLU A 183MET A 184GLU A 185 | ADN A 251 |
3U40_B_ADNB251 | 3u40 | ADN DB00640(Adenosine) | Entamoebahistolytica | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 10 | HIS C 9ARG C 48MET B 69ARG B 92SER B 95VAL B 182GLU B 183MET B 184GLU B 185CYS B 210 | ADN B 251 |
3U40_C_ADNC251 | 3u40 | ADN DB00640(Adenosine) | Entamoebahistolytica | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 12 | HIS B 9ARG B 48MET C 69ARG C 92SER C 95GLY C 97VAL C 182GLU C 183MET C 184GLU C 185ASP C 208CYS C 210 | ADN C 251 |
3U40_D_ADND251 | 3u40 | ADN DB00640(Adenosine) | Entamoebahistolytica | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 11 | HIS E 9ARG E 48MET D 69ARG D 92SER D 95GLY D 97VAL D 182GLU D 183MET D 184GLU D 185ASP D 208 | ADN D 251 |
3U40_E_ADNE251 | 3u40 | ADN DB00640(Adenosine) | Entamoebahistolytica | PURINE NUCLEOSIDEPHOSPHORYLASE | no annotation | 12 | HIS D 9ARG D 48MET E 69ARG E 92SER E 95GLY E 97VAL E 182GLU E 183MET E 184GLU E 185ASP E 208CYS E 210 | ADN E 251 |
3U40_F_ADNF251 | 3u40 | ADN DB00640(Adenosine) | Entamoebahistolytica | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1)no annotation | 10 | HIS A 9ARG A 48MET F 69ARG F 92SER F 95VAL F 182GLU F 183MET F 184GLU F 185ASP F 208 | ADN F 251 |
3UAW_A_ADNA236 | 3uaw | ADN DB00640(Adenosine) | Bacillus cereus | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | PF01048(PNP_UDP_1) | 11 | MET A 64ARG A 87THR A 90GLY A 92VAL A 178GLU A 179MET A 180GLU A 181SER A 203ASP A 204ILE A 206 | ADN A 236 |
3UAY_A_ADNA236 | 3uay | ADN DB00640(Adenosine) | Bacillus cereus | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | PF01048(PNP_UDP_1) | 10 | MET A 64ARG A 87THR A 90GLY A 92VAL A 178GLU A 179MET A 180GLU A 181ASN A 204ILE A 206 | ADN A 236 |
4D9H_A_ADNA301 | 4d9h | ADN DB00640(Adenosine) | Bacillus subtilis | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | PF01048(PNP_UDP_1)no annotation | 13 | HIS B 4ARG B 43MET A 64ARG A 87SER A 90GLY A 92VAL A 177GLU A 178MET A 179GLU A 180SER A 202ASP A 203VAL A 205 | ADN A 301 |
4DA6_A_GA2A301 | 4da6 | GA2 DB01004(Ganciclovir) | Bacillus subtilis | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | PF01048(PNP_UDP_1) | 9 | MET A 64SER A 90GLY A 92VAL A 177MET A 179GLU A 180SER A 202ASP A 203VAL A 205 | GA2 A 301 |
4DA7_A_AC2A301 | 4da7 | AC2 DB00787(Aciclovir) | Bacillus subtilis | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | PF01048(PNP_UDP_1) | 10 | MET A 64ARG A 87GLY A 92ALA A 156VAL A 177GLU A 178MET A 179GLU A 180SER A 202VAL A 205 | AC2 A 301 |
4DAN_A_2FAA301 | 4dan | 2FA DB01073(Fludarabine) | Bacillus subtilis | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | PF01048(PNP_UDP_1)no annotation | 13 | HIS B 4ARG B 43MET A 64ARG A 87SER A 90GLY A 92VAL A 177GLU A 178MET A 179GLU A 180SER A 202ASP A 203VAL A 205 | 2FA A 301 |
4DAN_B_2FAB301 | 4dan | 2FA DB01073(Fludarabine) | Bacillus subtilis | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | PF01048(PNP_UDP_1)no annotation | 12 | HIS A 4ARG A 43ARG B 87SER B 90GLY B 92VAL B 177GLU B 178MET B 179GLU B 180SER B 202ASP B 203VAL B 205 | 2FA B 301 |
5I3C_A_AC2A301 | 5i3c | AC2 DB00787(Aciclovir) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | PF01048(PNP_UDP_1) | 9 | MET A 64ARG A 87SER A 90GLY A 92ALA A 156VAL A 178MET A 180GLU A 181ILE A 206 | AC2 A 301 |
5I3C_B_AC2B301 | 5i3c | AC2 DB00787(Aciclovir) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | no annotation | 10 | MET B 64SER B 90GLY B 92ALA B 156VAL B 178GLU B 179MET B 180GLU B 181ASP B 204ILE B 206 | AC2 B 301 |
5I3C_C_AC2C301 | 5i3c | AC2 DB00787(Aciclovir) | Escherichia coli | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE | no annotation | 11 | MET C 64SER C 90GLY C 92ALA C 156VAL C 178GLU C 179MET C 180GLU C 181SER C 203ASP C 204ILE C 206 | AC2 C 301 |
5ZNC_A_QI9A301 | 5znc | QI9 DB00468(Quinine) | Plasmodiumfalciparum | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 9 | VAL A 66SER A 91GLY A 93TYR A 160VAL A 181GLU A 182MET A 183TRP A 212ASP A 218 | QI9 A 301 |
5ZNI_A_YMZA302 | 5zni | YMZ DB00358(Mefloquine) | Plasmodiumfalciparum | PURINE NUCLEOSIDEPHOSPHORYLASE | PF01048(PNP_UDP_1) | 9 | VAL A 66GLY A 93TYR A 160VAL A 181GLU A 182MET A 183ASP A 206GLY A 207PRO A 209 | YMZ A 302 |