DRUG BINDING INTERFACES MAPPED TO 'NUCLEASE'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
Filter list by:
All hits
Sort hits by ligand
Sort hits by residue numbers
Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
1DY5_A_ACTA600
1dy5
ACT
DB03166(Aceticacid)
Bos taurus
RIBONUCLEASE A
PF00074(RnaseA)
4
HIS A 12VAL A 43ASN A 44THR A 45
ACT A 600
1DY5_B_ACTB602
1dy5
ACT
DB03166(Aceticacid)
Bos taurus
RIBONUCLEASE A
None
4
SER B 21TYR B 25GLN B 28MET B 29
ACT B 602
1N3Z_A_ADNA126
1n3z
ADN
DB00640(Adenosine)
Bos taurus
RIBONUCLEASE,SEMINAL
PF00074(RnaseA)
9
ALA A 4LYS A 7CYS A 65ASN A 67GLN A 69ASN A 71ALA A 109VAL A 118HIS A 119
ADN A 126
2HND_A_NVPA999
2hnd
NVP
DB00238(Nevirapine)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
10
LEU A 100LYS A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
NVP A 999
2HNY_A_NVPA999
2hny
NVP
DB00238(Nevirapine)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
10
LEU A 100LYS A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
NVP A 999
2ZD1_A_T27A557
2zd1
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 557
2ZE2_A_T27A556
2ze2
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
10
PRO A 95ILE A 100ASN A 103VAL A 179TYR A 181TYR A 188PRO A 225TRP A 229LEU A 234TYR A 318
T27 A 556
3BGR_A_T27A556
3bgr
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
11
LEU A 100ASN A 103GLU B 138VAL A 179CYS A 181TYR A 183TYR A 188PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 556
3LP0_A_NVPA701
3lp0
NVP
DB00238(Nevirapine)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
9
LEU A 100VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
NVP A 701
3LP1_A_NVPA701
3lp1
NVP
DB00238(Nevirapine)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
10
LEU A 100ASN A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
NVP A 701
3M8P_A_65BA562
3m8p
65B
DB06414(Etravirine)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H;P51 RT
PF00075(RNase_H)PF00078(RVT_thumb)PF06815(RVT_1)PF06817(RVT_connect)PF00078(RVT_thumb)PF06815(RVT_1)PF06817(RVT_connect)
11
LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PHE A 227TRP A 229LEU A 234TYR A 318
65B A 562
3QLH_A_T27A555
3qlh
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
12
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229PRO A 236TYR A 318
T27 A 555
4B3O_A_EFZA1557
4b3o
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
9
LEU A 100LYS A 101LYS A 103VAL A 106TYR A 181TYR A 188GLY A 190LEU A 234TYR A 318
EFZ A1557
4B3Q_A_NVPA999
4b3q
NVP
DB00238(Nevirapine)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
7
LEU A 100LYS A 103VAL A 106TYR A 181TYR A 188LEU A 234TYR A 318
NVP A 999
4G1Q_A_T27A601
4g1q
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
15
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4ICL_A_T27A601
4icl
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 601
4ID5_A_T27A601
4id5
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4IDK_A_T27A601
4idk
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 601
4IFV_A_T27A601
4ifv
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
EXORIBONUCLEASE H,P66 RT;GAG-POL POLYPROTEIN
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4IFY_A_T27A601
4ify
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4IG3_A_T27A601
4ig3
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4KFB_A_T27A607
4kfb
T27
DB08864(Rilpivirine)
Humanimmunodeficiencyvirus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H,EXORIBONUCLEA P66 RT
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 607
5B2O_A_ACTA1728
5b2o
ACT
DB03166(Aceticacid)
Francisellatularensis
CRISPR-ASSOCIATEDENDONUCLEASE CAS9
None
5
GLN A 92THR A1458TRP A1459ASP A1460ASN A1462
ACT A1728
5B2O_B_ACTB120
5b2o
ACT
DB03166(Aceticacid)
Francisellatularensis;syntheticconstruct
CRISPR-ASSOCIATEDENDONUCLEASE CAS9;GUIDE RNA
None
4
ASN A1248SER A1368ARG A1370PRO A1444
ACT B 120
5B2P_A_ACTA1728
5b2p
ACT
DB03166(Aceticacid)
Francisellatularensis
CRISPR-ASSOCIATEDENDONUCLEASE CAS9
None
5
GLN A 92THR A1458TRP A1459ASP A1460ASN A1462
ACT A1728
5B2P_B_ACTB120
5b2p
ACT
DB03166(Aceticacid)
Francisellatularensis;syntheticconstruct
CRISPR-ASSOCIATEDENDONUCLEASE CAS9;GUIDE RNA
None
4
ASN A1248SER A1368ARG A1370PRO A1444
ACT B 120
5B2Q_A_ACTA1728
5b2q
ACT
DB03166(Aceticacid)
Francisellatularensis
CRISPR-ASSOCIATEDENDONUCLEASE CAS9
None
3
ASN A1248SER A1368ARG A1370
ACT A1728
5B2Q_A_ACTA1729
5b2q
ACT
DB03166(Aceticacid)
Francisellatularensis
CRISPR-ASSOCIATEDENDONUCLEASE CAS9
None
5
GLN A 92THR A1458TRP A1459ASP A1460ASN A1462
ACT A1729
5B2S_A_ACTA107
5b2s
ACT
DB03166(Aceticacid)
Streptococcuspyogenes
CRISPR-ASSOCIATEDENDONUCLEASE CAS9;GUIDE RNA
NonePF13395(Cas9-BH)PF16592(Cas9_REC)PF16593(Cas9_PI)PF16595(HNH_4)
3
VAL B1100THR B1102ARG B1171
ACT A 107
5B2T_A_ACTA108
5b2t
ACT
DB03166(Aceticacid)
Streptococcuspyogenes
CRISPR-ASSOCIATEDENDONUCLEASE CAS9;GUIDE RNA
NonePF13395(Cas9-BH)PF16592(Cas9_REC)PF16593(Cas9_PI)PF16595(HNH_4)
3
VAL B1100THR B1102ARG B1171
ACT A 108
5HBM_A_NVPA601
5hbm
NVP
DB00238(Nevirapine)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
11
PRO A 95LEU A 100LYS A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
NVP A 601
5NFJ_A_SAMA501
5nfj
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
MITOCHONDRIALRIBONUCLEASE PPROTEIN 1
PF01746(tRNA_m1G_MT)
14
LEU A 290THR A 291ALA A 292ILE A 309GLY A 310ASP A 314THR A 321SER A 322LEU A 336LEU A 338ASN A 350LEU A 351LEU A 353MET A 356
SAM A 501
5NFJ_B_SAMB501
5nfj
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
MITOCHONDRIALRIBONUCLEASE PPROTEIN 1
None
12
LEU B 290ALA B 292ILE B 309GLY B 310ASP B 314THR B 321SER B 322LEU B 336LEU B 338ASN B 350LEU B 351MET B 356
SAM B 501
5NFJ_C_SAMC501
5nfj
SAM
DB00118(S-Adenosylmethionine)
Homo sapiens
MITOCHONDRIALRIBONUCLEASE PPROTEIN 1
None
12
LEU C 290ALA C 292ILE C 309GLY C 310ASP C 314THR C 321SER C 322LEU C 336LEU C 338ASN C 350LEU C 351MET C 356
SAM C 501
[["1DY5_A_ACTA600","1dy5","ACT","DB03166(Acetic acid)","Bos taurus","RIBONUCLEASE A","PF00074(RnaseA)",4,"HIS A 12;VAL A 43;ASN A 44;THR A 45","ACT A 600\r"],["1DY5_B_ACTB602","1dy5","ACT","DB03166(Acetic acid)","Bos taurus","RIBONUCLEASE A","None",4,"SER B 21;TYR B 25;GLN B 28;MET B 29","ACT B 602\r"],["1N3Z_A_ADNA126","1n3z","ADN","DB00640(Adenosine)","Bos taurus","RIBONUCLEASE, SEMINAL","PF00074(RnaseA)",9,"ALA A 4;LYS A 7;CYS A 65;ASN A 67;GLN A 69;ASN A 71;ALA A 109;VAL A 118;HIS A 119","ADN A 126\r"],["2HND_A_NVPA999","2hnd","NVP","DB00238(Nevirapine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","NVP A 999\r"],["2HNY_A_NVPA999","2hny","NVP","DB00238(Nevirapine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","NVP A 999\r"],["2ZD1_A_T27A557","2zd1","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 557\r"],["2ZE2_A_T27A556","2ze2","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"PRO A 95;ILE A 100;ASN A 103;VAL A 179;TYR A 181;TYR A 188;PRO A 225;TRP A 229;LEU A 234;TYR A 318","T27 A 556\r"],["3BGR_A_T27A556","3bgr","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",11,"LEU A 100;ASN A 103;GLU B 138;VAL A 179;CYS A 181;TYR A 183;TYR A 188;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 556\r"],["3LP0_A_NVPA701","3lp0","NVP","DB00238(Nevirapine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",9,"LEU A 100;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","NVP A 701\r"],["3LP1_A_NVPA701","3lp1","NVP","DB00238(Nevirapine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"LEU A 100;ASN A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","NVP A 701\r"],["3M8P_A_65BA562","3m8p","65B","DB06414(Etravirine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H;P51 RT","PF00075(RNase_H);PF00078(RVT_thumb);PF06815(RVT_1);PF06817(RVT_connect);PF00078(RVT_thumb);PF06815(RVT_1);PF06817(RVT_connect)",11,"LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PHE A 227;TRP A 229;LEU A 234;TYR A 318","65B A 562\r"],["3QLH_A_T27A555","3qlh","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",12,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;PRO A 236;TYR A 318","T27 A 555\r"],["4B3O_A_EFZA1557","4b3o","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",9,"LEU A 100;LYS A 101;LYS A 103;VAL A 106;TYR A 181;TYR A 188;GLY A 190;LEU A 234;TYR A 318","EFZ A1557\r"],["4B3Q_A_NVPA999","4b3q","NVP","DB00238(Nevirapine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",7,"LEU A 100;LYS A 103;VAL A 106;TYR A 181;TYR A 188;LEU A 234;TYR A 318","NVP A 999\r"],["4G1Q_A_T27A601","4g1q","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",15,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4ICL_A_T27A601","4icl","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 601\r"],["4ID5_A_T27A601","4id5","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4IDK_A_T27A601","4idk","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 601\r"],["4IFV_A_T27A601","4ifv","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","EXORIBONUCLEASE H, P66 RT;GAG-POL POLYPROTEIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4IFY_A_T27A601","4ify","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4IG3_A_T27A601","4ig3","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4KFB_A_T27A607","4kfb","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H, EXORIBONUCLEA P66 RT","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 607\r"],["5B2O_A_ACTA1728","5b2o","ACT","DB03166(Acetic acid)","Francisella tularensis","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","None",5,"GLN A 92;THR A1458;TRP A1459;ASP A1460;ASN A1462","ACT A1728\r"],["5B2O_B_ACTB120","5b2o","ACT","DB03166(Acetic acid)","Francisella tularensis;synthetic construct","CRISPR-ASSOCIATED ENDONUCLEASE CAS9;GUIDE RNA","None",4,"ASN A1248;SER A1368;ARG A1370;PRO A1444","ACT B 120\r"],["5B2P_A_ACTA1728","5b2p","ACT","DB03166(Acetic acid)","Francisella tularensis","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","None",5,"GLN A 92;THR A1458;TRP A1459;ASP A1460;ASN A1462","ACT A1728\r"],["5B2P_B_ACTB120","5b2p","ACT","DB03166(Acetic acid)","Francisella tularensis;synthetic construct","CRISPR-ASSOCIATED ENDONUCLEASE CAS9;GUIDE RNA","None",4,"ASN A1248;SER A1368;ARG A1370;PRO A1444","ACT B 120\r"],["5B2Q_A_ACTA1728","5b2q","ACT","DB03166(Acetic acid)","Francisella tularensis","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","None",3,"ASN A1248;SER A1368;ARG A1370","ACT A1728\r"],["5B2Q_A_ACTA1729","5b2q","ACT","DB03166(Acetic acid)","Francisella tularensis","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","None",5,"GLN A 92;THR A1458;TRP A1459;ASP A1460;ASN A1462","ACT A1729\r"],["5B2S_A_ACTA107","5b2s","ACT","DB03166(Acetic acid)","Streptococcus pyogenes","CRISPR-ASSOCIATED ENDONUCLEASE CAS9;GUIDE RNA","None;PF13395(Cas9-BH);PF16592(Cas9_REC);PF16593(Cas9_PI);PF16595(HNH_4)",3,"VAL B1100;THR B1102;ARG B1171","ACT A 107\r"],["5B2T_A_ACTA108","5b2t","ACT","DB03166(Acetic acid)","Streptococcus pyogenes","CRISPR-ASSOCIATED ENDONUCLEASE CAS9;GUIDE RNA","None;PF13395(Cas9-BH);PF16592(Cas9_REC);PF16593(Cas9_PI);PF16595(HNH_4)",3,"VAL B1100;THR B1102;ARG B1171","ACT A 108\r"],["5HBM_A_NVPA601","5hbm","NVP","DB00238(Nevirapine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",11,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","NVP A 601\r"],["5NFJ_A_SAMA501","5nfj","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","MITOCHONDRIAL RIBONUCLEASE P PROTEIN 1","PF01746(tRNA_m1G_MT)",14,"LEU A 290;THR A 291;ALA A 292;ILE A 309;GLY A 310;ASP A 314;THR A 321;SER A 322;LEU A 336;LEU A 338;ASN A 350;LEU A 351;LEU A 353;MET A 356","SAM A 501\r"],["5NFJ_B_SAMB501","5nfj","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","MITOCHONDRIAL RIBONUCLEASE P PROTEIN 1","None",12,"LEU B 290;ALA B 292;ILE B 309;GLY B 310;ASP B 314;THR B 321;SER B 322;LEU B 336;LEU B 338;ASN B 350;LEU B 351;MET B 356","SAM B 501\r"],["5NFJ_C_SAMC501","5nfj","SAM","DB00118(S-Adenosylmethionine)","Homo sapiens","MITOCHONDRIAL RIBONUCLEASE P PROTEIN 1","None",12,"LEU C 290;ALA C 292;ILE C 309;GLY C 310;ASP C 314;THR C 321;SER C 322;LEU C 336;LEU C 338;ASN C 350;LEU C 351;MET C 356","SAM C 501\r"]]