DRUG BINDING INTERFACES MAPPED TO 'MITOGEN-ACTIVATED PROTEIN KINASE 14'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
3GCS_A_BAXA401 | 3gcs | BAX DB00398(Sorafenib) | Homo sapiens | MITOGEN-ACTIVATEDPROTEIN KINASE 14 | PF00069(Pkinase) | 18 | VAL A 38ALA A 51ARG A 70GLU A 71LEU A 74LEU A 75MET A 78VAL A 83ILE A 84THR A 106LEU A 108MET A 109ILE A 141ILE A 146HIS A 148ILE A 166LEU A 167ASP A 168 | BAX A 401 |
3HEC_A_STIA1 | 3hec | STI DB00619(Imatinib) | Homo sapiens | MITOGEN-ACTIVATEDPROTEIN KINASE 14 | PF00069(Pkinase) | 16 | VAL A 30ALA A 51LYS A 53GLU A 71LEU A 74LEU A 75ILE A 84LEU A 104THR A 106LEU A 108MET A 109ILE A 146ASP A 150LEU A 167ASP A 168PHE A 169 | STI A 1 |
3HEG_A_BAXA1 | 3heg | BAX DB00398(Sorafenib) | Homo sapiens | MITOGEN-ACTIVATEDPROTEIN KINASE 14 | PF00069(Pkinase) | 18 | VAL A 30VAL A 38ALA A 51LYS A 53GLU A 71LEU A 74LEU A 75MET A 78VAL A 83ILE A 84THR A 106MET A 109ILE A 141ILE A 146HIS A 148ILE A 166LEU A 167ASP A 168 | BAX A 1 |
3LFA_A_1N1A361 | 3lfa | 1N1 DB01254(Dasatinib) | Homo sapiens | MITOGEN-ACTIVATEDPROTEIN KINASE 14 | PF00069(Pkinase) | 8 | VAL A 30ALA A 51LYS A 53GLU A 71LEU A 104THR A 106LEU A 108MET A 109 | 1N1 A 361 |