DRUG BINDING INTERFACES MAPPED TO 'METHYLENETETRAHYDROFOLATE REDUCTASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1ZP4_A_C2FA995 | 1zp4 | C2F DB11256(Levomefolicacid) | Escherichia coli | 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE | PF02219(MTHFR) | 9 | GLN A 28ASP A 120GLN A 183GLN A 219PHE A 223THR A 227TYR A 275LEU A 277ARG A 279 | C2F A 995 |
1ZP4_B_C2FB996 | 1zp4 | C2F DB11256(Levomefolicacid) | Escherichia coli | 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE | None | 10 | GLN B 28ASP B 120GLN B 183SER B 215GLN B 219PHE B 223THR B 227TYR B 275LEU B 277ARG B 279 | C2F B 996 |
1ZP4_C_C2FC997 | 1zp4 | C2F DB11256(Levomefolicacid) | Escherichia coli | 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE | None | 10 | GLN C 28ASP C 120GLN C 183SER C 215GLN C 219PHE C 223THR C 227TYR C 275LEU C 277ARG C 279 | C2F C 997 |
3APT_B_ACTB311 | 3apt | ACT DB03166(Aceticacid) | Thermusthermophilus | METHYLENETETRAHYDROFOLATE REDUCTASE | None | 9 | GLU B 18HIS B 77LEU B 104ASP B 109PRO B 110ALA B 147ILE B 178HIS B 270TYR B 272 | ACT B 311 |
3FSU_A_C2FA995 | 3fsu | C2F DB11256(Levomefolicacid) | Escherichia coli | 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE | PF02219(MTHFR) | 13 | GLN A 28THR A 59ASP A 120GLN A 183LEU A 212SER A 215ASN A 216GLN A 219LEU A 223THR A 227TYR A 275LEU A 277ARG A 279 | C2F A 995 |
3FSU_E_C2FE995 | 3fsu | C2F DB11256(Levomefolicacid) | Escherichia coli | 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE | None | 11 | GLN E 28THR E 59ASP E 120GLN E 183SER E 215GLN E 219LEU E 223THR E 227TYR E 275LEU E 277ARG E 279 | C2F E 995 |