DRUG BINDING INTERFACES MAPPED TO 'METHYL TRANSFERASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1RJD_A_SAMA801 | 1rjd | SAM DB00118(S-Adenosylmethionine) | Saccharomycescerevisiae | CARBOXY METHYLTRANSFERASE FORPROTEIN PHOSPHATASE2A CATALYTIC SUBUNIT | PF04072(LCM) | 18 | ILE A 5GLN A 6THR A 8ASP A 9ALA A 12ARG A 81GLY A 105GLY A 107ASP A 128TYR A 129SER A 132ASP A 175LEU A 176ASN A 177GLU A 201CYS A 202LEU A 203TYR A 206 | SAM A 801 |
1RJD_B_SAMB802 | 1rjd | SAM DB00118(S-Adenosylmethionine) | Saccharomycescerevisiae | CARBOXY METHYLTRANSFERASE FORPROTEIN PHOSPHATASE2A CATALYTIC SUBUNIT | None | 18 | ILE B 5GLN B 6THR B 8ASP B 9ALA B 12ARG B 81GLY B 105GLY B 107ASP B 128TYR B 129SER B 132ASP B 175LEU B 176ASN B 177GLU B 201CYS B 202LEU B 203TYR B 206 | SAM B 802 |
1RJD_C_SAMC803 | 1rjd | SAM DB00118(S-Adenosylmethionine) | Saccharomycescerevisiae | CARBOXY METHYLTRANSFERASE FORPROTEIN PHOSPHATASE2A CATALYTIC SUBUNIT | None | 18 | ILE C 5GLN C 6THR C 8ASP C 9ALA C 12ARG C 81GLY C 105GLY C 107ASP C 128TYR C 129SER C 132ASP C 175LEU C 176ASN C 177GLU C 201CYS C 202LEU C 203TYR C 206 | SAM C 803 |
2REZ_A_ACTA155 | 2rez | ACT DB03166(Aceticacid) | Streptomycesglaucescens | MULTIFUNCTIONALCYCLASE-DEHYDRATASE-3-O-METHYLTRANSFERASE TCMN | PF03364(Polyketide_cyc) | 5 | TRP A 65ARG A 82GLY A 86PRO A 87PHE A 88 | ACT A 155 |
2REZ_A_ACTA156 | 2rez | ACT DB03166(Aceticacid) | Streptomycesglaucescens | MULTIFUNCTIONALCYCLASE-DEHYDRATASE-3-O-METHYLTRANSFERASE TCMN | PF03364(Polyketide_cyc) | 7 | GLU A 34THR A 54TRP A 63TRP A 65ARG A 82MET A 125LEU A 129 | ACT A 156 |
3IHT_A_SAMA200 | 3iht | SAM DB00118(S-Adenosylmethionine) | Ruegeria pomeroyi | S-ADENOSYL-L-METHIONINE METHYLTRANSFERASE | PF12692(Methyltransf_17) | 13 | GLY A 47GLY A 49ASN A 50GLY A 51ARG A 52THR A 53GLU A 70ARG A 71ASP A 90ILE A 91ASP A 112LEU A 113PHE A 124 | SAM A 200 |
3R24_A_SAMA302 | 3r24 | SAM DB00118(S-Adenosylmethionine) | Severe acuterespiratorysyndrome-relatedcoronavirus | 2'-O-METHYLTRANSFERASE | PF06460(NSP13) | 15 | ASN A 43TYR A 47GLY A 71SER A 74PRO A 80GLY A 81ASP A 99LEU A 100ASN A 101ASP A 114CYS A 115ASP A 130MET A 131PHE A 149LYS A 170 | SAM A 302 |
5IKM_A_SAMA311 | 5ikm | SAM DB00118(S-Adenosylmethionine) | Dengue virus | NS5 METHYLTRANSFERASE | PF01728(FtsJ) | 13 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110ASP A 131VAL A 132ASP A 146ILE A 147 | SAM A 311 |