DRUG BINDING INTERFACES MAPPED TO 'MATRIX PROTEIN'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1FBM_B_RTLB951 1fbm RTL

DB00162
(Vitamin
A) 		Rattus norvegicus PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN) 		None
PF11598
(COMP) 		19 THR D  40
THR A  40
THR B  40
THR E  40
LEU C  44
LEU A  44
LEU E  44
LEU B  44
LEU D  44
VAL D  47
VAL C  47
VAL E  47
VAL B  47
LEU A  51
LEU E  51
LEU D  51
LEU B  51
GLN A  54
GLN E  54
 RTL B 951
1MZ9_A_VDYA1002 1mz9 VDY

DB00146
(Calcidiol) 		Mus musculus CARTILAGE OLIGOMERIC
MATRIX PROTEIN 		PF11598
(COMP)
no annotation 		21 ILE B  58
ILE A  58
ILE C  58
LEU D  61
LEU C  61
LEU E  61
LEU B  61
LEU A  61
VAL E  65
VAL A  65
VAL C  65
VAL D  65
VAL B  65
CYS D  68
CYS E  68
ALA A  70
ALA E  70
ALA D  70
ALA C  70
CYS C  71
CYS D  71
 VDY A1002
1MZ9_D_VDYD1001 1mz9 VDY

DB00146
(Calcidiol) 		Mus musculus CARTILAGE OLIGOMERIC
MATRIX PROTEIN 		PF11598
(COMP)
no annotation 		16 LEU A  37
THR D  40
THR C  40
THR A  40
THR E  40
LEU C  44
LEU E  44
LEU B  44
LEU D  44
VAL D  47
VAL E  47
VAL B  47
LEU A  51
LEU C  51
LEU D  51
LEU B  51
 VDY D1001
2KAD_A_308A1 2kad 308

DB00915
(Amantadine) 		Influenza A virus TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2 		PF00599
(Flu_M2)
no annotation 		9 SER A  31
SER D  31
SER C  31
SER B  31
GLY D  34
GLY A  34
ILE A  35
LEU B  38
LEU C  38
 308 A   1
2PXC_A_SAMA500 2pxc SAM

DB00118
(S-
Adenosylmethionine) 		Murray Valley
encephalitis
virus 		GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN);
ENVELOPE PROTEIN M
(MATRIX PROTEIN);
MAJOR ENVELOPE
PROTEIN E;
NON-STRUCTURAL
PROTEIN 1 (NS1);
NON-STRUCTURAL
PROTEIN 2A (NS2A);
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT;
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT;
NON-STRUCTURAL
PROTEIN 4A (NS4A);
NON-STRUCTURAL
PROTEIN 4B (NS4B);
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)] 		PF01728
(FtsJ) 		14 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM A 500
2RLF_A_RIMA199 2rlf RIM

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 PF00599
(Flu_M2)
no annotation 		6 LEU A  40
TRP B  41
ILE B  42
LEU A  43
ASP A  44
ARG B  45
 RIM A 199
2RLF_B_RIMB299 2rlf RIM

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 no annotation 6 LEU B  40
TRP C  41
ILE C  42
LEU B  43
ASP B  44
ARG C  45
 RIM B 299
2RLF_C_RIMC399 2rlf RIM

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 no annotation 6 LEU C  40
TRP D  41
ILE D  42
LEU C  43
ASP C  44
ARG D  45
 RIM C 399
2RLF_D_RIMD499 2rlf RIM

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 PF00599
(Flu_M2)
no annotation 		6 LEU D  40
TRP A  41
ILE A  42
ASP D  44
ARG A  45
LEU A  46
 RIM D 499
6BKK_B_308B101 6bkk 308

DB00915
(Amantadine) 		Influenza A virus MATRIX PROTEIN 2 None
PF00599
(Flu_M2) 		6 VAL A  27
ALA C  30
SER A  31
SER D  31
SER C  31
SER B  31
 308 B 101
6BKK_F_308F101 6bkk 308

DB00915
(Amantadine) 		Influenza A virus MATRIX PROTEIN 2 None 6 VAL E  27
ALA F  30
SER G  31
SER F  31
SER H  31
SER E  31
 308 F 101
6BKL_C_EU7C101 6bkl EU7

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 None
PF00599
(Flu_M2) 		9 VAL C  27
VAL D  27
ALA C  30
ALA B  30
SER A  31
SER D  31
SER C  31
SER B  31
GLY D  34
 EU7 C 101
6BKL_D_RIMD101 6bkl RIM

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 None
PF00599
(Flu_M2) 		9 VAL D  27
ALA C  30
ALA B  30
ALA D  30
SER A  31
SER D  31
SER C  31
SER B  31
GLY A  34
 RIM D 101
6BKL_F_RIMF101 6bkl RIM

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 None 9 ALA G  30
ALA F  30
ALA E  30
SER G  31
SER F  31
SER H  31
SER E  31
GLY F  34
GLY E  34
 RIM F 101
6BKL_G_EU7G101 6bkl EU7

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 None 9 ALA F  30
ALA G  30
ALA E  30
SER G  31
SER F  31
SER H  31
SER E  31
GLY F  34
GLY G  34
 EU7 G 101
6BOC_A_EU7A102 6boc EU7

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 None
PF00599
(Flu_M2) 		6 ALA C  30
ALA D  30
SER A  31
SER D  31
SER C  31
SER B  31
 EU7 A 102
6BOC_C_RIMC101 6boc RIM

DB00478
(Rimantadine) 		Influenza A virus MATRIX PROTEIN 2 None
PF00599
(Flu_M2) 		6 ALA C  30
ALA D  30
SER A  31
SER D  31
SER C  31
SER B  31
 RIM C 101