DRUG BINDING INTERFACES MAPPED TO 'M PROTEIN'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
2OKC_A_SAMA500 2okc SAM

DB00118
(S-
Adenosylmethionine)
Bacteroides
thetaiotaomicron
TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN
PF02384
(HsdM_N)
PF12161
(N6_Mtase)
18 TYR A 152
THR A 154
ARG A 156
ILE A 159
ALA A 178
GLY A 180
THR A 181
GLY A 183
ASP A 214
ASN A 215
THR A 216
VAL A 219
ASP A 243
SER A 244
ASN A 259
PRO A 261
ARG A 265
PHE A 288
SAM A 500
2OKC_B_SAMB500 2okc SAM

DB00118
(S-
Adenosylmethionine)
Bacteroides
thetaiotaomicron
TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN
None 18 TYR B 152
THR B 154
ARG B 156
ILE B 159
ALA B 178
GLY B 180
THR B 181
GLY B 183
ASP B 214
ASN B 215
THR B 216
VAL B 219
ASP B 243
SER B 244
ASN B 259
PRO B 261
ARG B 265
PHE B 288
SAM B 500
2Y7H_B_SAMB530 2y7h SAM

DB00118
(S-
Adenosylmethionine)
Escherichia coli TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN
PF02384
(HsdM_N)
PF12161
(N6_Mtase)
15 TYR B 149
THR B 151
ILE B 156
ALA B 175
GLY B 177
THR B 178
GLY B 180
GLU B 216
ASN B 248
THR B 249
LEU B 250
ASN B 266
PRO B 268
THR B 275
PHE B 292
SAM B 530
2Y7H_C_SAMC530 2y7h SAM

DB00118
(S-
Adenosylmethionine)
Escherichia coli TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN
None 15 TYR C 149
THR C 151
ILE C 156
ALA C 175
GLY C 177
THR C 178
GLY C 180
GLU C 216
ASN C 248
THR C 249
LEU C 250
ASN C 266
PRO C 268
THR C 275
PHE C 292
SAM C 530
3MYU_A_VIBA500 3myu VIB

DB00152
(Thiamine)
Mycoplasma
genitalium
HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
PF06646
(Mycoplasma_p37)
10 ASP A  41
HIS A  42
ASN A  95
TYR A 176
ASP A 269
TRP A 275
TYR A 307
ASP A 308
ILE A 343
GLY A 344
VIB A 500
3MYU_B_VIBB500 3myu VIB

DB00152
(Thiamine)
Mycoplasma
genitalium
HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
no annotation 10 ASP B  41
HIS B  42
ASN B 161
TYR B 176
ASP B 269
TRP B 275
TYR B 307
ASP B 308
ILE B 343
GLY B 344
VIB B 500