DRUG BINDING INTERFACES MAPPED TO 'HYPOTHETICAL PROTEIN'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1GYX_A_BEZA1077 | 1gyx | BEZ DB03793(BenzoicAcid) | Escherichia coli | HYPOTHETICAL PROTEINYDCE | NonePF01361(Tautomerase) | 7 | PRO B 1CYS A 7PHE A 8ARG A 10SER B 38TRP A 51TYR A 72 | BEZ A1077 |
1I9G_A_SAMA301 | 1i9g | SAM DB00118(S-Adenosylmethionine) | Mycobacteriumtuberculosis | HYPOTHETICAL PROTEINRV2118C | PF08704(GCD14_N)PF14801(GCD14) | 15 | ILE A 83GLY A 107GLY A 109SER A 110ALA A 112LEU A 113GLU A 131GLN A 132ARG A 133HIS A 136ASP A 161LEU A 162ASP A 178MET A 179VAL A 185 | SAM A 301 |
1NB9_A_RBFA401 | 1nb9 | RBF DB00140(Riboflavin) | Homo sapiens | HYPOTHETICAL PROTEINFLJ11149 | PF01687(Flavokinase) | 9 | THR A 34ILE A 53VAL A 69SER A 71GLU A 86ARG A 111LEU A 122ILE A 126ASP A 129 | RBF A 401 |
1VE3_A_SAMA302 | 1ve3 | SAM DB00118(S-Adenosylmethionine) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0226 | PF13649(Methyltransf_25) | 16 | TYR A 7TYR A 13TYR A 21ARG A 24ALA A 46GLY A 48ASP A 67ILE A 68SER A 69ASP A 93ALA A 94ARG A 95ILE A 110SER A 112HIS A 115PHE A 116 | SAM A 302 |
1VE3_B_SAMB301 | 1ve3 | SAM DB00118(S-Adenosylmethionine) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0226 | None | 16 | TYR B 7TYR B 13TYR B 21ARG B 24ALA B 46GLY B 48ASP B 67ILE B 68SER B 69ASP B 93ALA B 94ARG B 95ILE B 110SER B 112HIS B 115PHE B 116 | SAM B 301 |
1WU8_A_ADNA500 | 1wu8 | ADN DB00640(Adenosine) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0463 | PF01887(SAM_adeno_trans)no annotation | 9 | ASP A 7ARG A 40HIS A 41ASP A 68VAL A 71PHE B 181ASN B 183TYR B 212ASN B 235 | ADN A 500 |
1WU8_B_ADNB501 | 1wu8 | ADN DB00640(Adenosine) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0463 | no annotation | 11 | ASP B 7ARG B 40HIS B 41ILE B 67ASP B 68PRO B 69VAL B 71PHE C 181ASN C 183TYR C 212ASN C 235 | ADN B 501 |
1WU8_C_ADNC502 | 1wu8 | ADN DB00640(Adenosine) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0463 | PF01887(SAM_adeno_trans)no annotation | 7 | ARG C 40HIS C 41VAL C 71PHE A 181ASN A 183TYR A 212ASN A 235 | ADN C 502 |
2A15_A_NCAA1001 | 2a15 | NCA DB02701(Nicotinamide) | Mycobacteriumtuberculosis | HYPOTHETICAL PROTEINRV0760C | PF02136(NTF2) | 11 | SER A 16TRP A 17VAL A 20TRP A 28ASP A 40ILE A 68LEU A 73LEU A 93LEU A 95TYR A 113MET A 124 | NCA A1001 |
2B25_A_SAMA601 | 2b25 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HYPOTHETICAL PROTEIN | PF08704(GCD14) | 14 | THR A 84THR A 87GLY A 111GLY A 113GLY A 116MET A 117GLU A 135VAL A 136ARG A 137HIS A 140ASP A 173ILE A 174ASP A 192MET A 193 | SAM A 601 |
2B25_B_SAMB602 | 2b25 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HYPOTHETICAL PROTEIN | None | 15 | THR B 84THR B 87GLY B 111GLY B 113SER B 114GLY B 116MET B 117GLU B 135VAL B 136ARG B 137HIS B 140ASP B 173ILE B 174ASP B 192MET B 193 | SAM B 602 |
2DTT_A_H4BA1003 | 2dtt | H4B DB00360(Sapropterin) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0634 | PF01242(PTPS)no annotation | 10 | HIS A 15HIS A 27HIS A 29TYR C 45ASP C 48PHE C 49THR A 76THR A 77GLU A 78GLU A 105 | H4B A1003 |
2DTT_B_H4BB1001 | 2dtt | H4B DB00360(Sapropterin) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0634 | PF01242(PTPS)no annotation | 10 | ILE A 5GLU B 24HIS B 27TYR A 45ASP A 48PHE A 49THR B 76THR B 77GLU B 78GLU B 105 | H4B B1001 |
2DTT_C_H4BC1002 | 2dtt | H4B DB00360(Sapropterin) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0634 | no annotation | 6 | TYR B 45ASP B 48PHE B 49THR C 77GLU C 78GLU C 105 | H4B C1002 |
2DTT_D_H4BD1006 | 2dtt | H4B DB00360(Sapropterin) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0634 | no annotation | 10 | HIS D 15HIS D 27HIS D 29TYR F 45ASP F 48PHE F 49THR D 76THR D 77GLU D 78GLU D 105 | H4B D1006 |
2DTT_E_H4BE1004 | 2dtt | H4B DB00360(Sapropterin) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0634 | no annotation | 11 | HIS E 15VAL E 17HIS E 27HIS E 29TYR D 45PHE D 49LEU D 50THR E 76THR E 77GLU E 78GLU E 105 | H4B E1004 |
2DTT_F_H4BF1005 | 2dtt | H4B DB00360(Sapropterin) | Pyrococcushorikoshii | HYPOTHETICAL PROTEINPH0634 | no annotation | 9 | ILE E 5HIS F 29TYR E 45ASP E 48PHE E 49THR F 76THR F 77GLU F 78GLU F 105 | H4B F1005 |
2F8L_A_SAMA400 | 2f8l | SAM DB00118(S-Adenosylmethionine) | Listeriamonocytogenes | HYPOTHETICAL PROTEINLMO1582 | PF02384(N6_Mtase) | 16 | HIS A 95THR A 98ALA A 126GLY A 128THR A 129ASN A 131LEU A 132ASP A 154VAL A 155ASP A 156LEU A 159ASP A 180GLY A 181ASP A 196PRO A 198PHE A 226 | SAM A 400 |
2GL0_A_ADNA901 | 2gl0 | ADN DB00640(Adenosine) | Pyrobaculumaerophilum | CONSERVEDHYPOTHETICAL PROTEIN | PF04008(Adenosine_kin)no annotation | 10 | ASN B 20HIS A 27PHE A 28HIS A 85TRP B 95ILE B 97ALA B 117ASN B 118VAL B 163TYR B 165 | ADN A 901 |
2GL0_B_ADNB902 | 2gl0 | ADN DB00640(Adenosine) | Pyrobaculumaerophilum | CONSERVEDHYPOTHETICAL PROTEIN | no annotation | 11 | ASN C 20HIS B 27PHE B 28HIS B 85TRP C 95ILE C 97THR C 116ALA C 117ASN C 118VAL C 163TYR C 165 | ADN B 902 |
2GL0_C_ADNC903 | 2gl0 | ADN DB00640(Adenosine) | Pyrobaculumaerophilum | CONSERVEDHYPOTHETICAL PROTEIN | PF04008(Adenosine_kin)no annotation | 12 | ASN A 20HIS C 27PHE C 28SER C 56HIS C 85TRP A 95ILE A 97THR A 116ALA A 117ASN A 118VAL A 163TYR A 165 | ADN C 903 |
2GL0_D_ADND904 | 2gl0 | ADN DB00640(Adenosine) | Pyrobaculumaerophilum | CONSERVEDHYPOTHETICAL PROTEIN | no annotation | 12 | ASN E 20HIS D 27PHE D 28SER D 56HIS D 85TRP E 95ILE E 97THR E 116ALA E 117ASN E 118VAL E 163TYR E 165 | ADN D 904 |
2GL0_E_ADNE905 | 2gl0 | ADN DB00640(Adenosine) | Pyrobaculumaerophilum | CONSERVEDHYPOTHETICAL PROTEIN | no annotation | 11 | ASN F 20HIS E 27PHE E 28HIS E 85TRP F 95ILE F 97THR F 116ALA F 117ASN F 118VAL F 163TYR F 165 | ADN E 905 |
2GL0_F_ADNF906 | 2gl0 | ADN DB00640(Adenosine) | Pyrobaculumaerophilum | CONSERVEDHYPOTHETICAL PROTEIN | no annotation | 11 | ASN D 20HIS F 27PHE F 28HIS F 85TRP D 95ILE D 97THR D 116ALA D 117ASN D 118VAL D 163TYR D 165 | ADN F 906 |
2JB7_B_ACTB1169 | 2jb7 | ACT DB03166(Aceticacid) | Pyrobaculumaerophilum | HYPOTHETICAL PROTEINPAE2307 | NonePF04008(Adenosine_kin) | 3 | ARG C 111ARG B 111ARG A 111 | ACT B1169 |
2Q6O_A_SAMA500 | 2q6o | SAM DB00118(S-Adenosylmethionine) | Salinisporatropica | HYPOTHETICAL PROTEIN | PF01887(SAM_adeno_trans) | 7 | ASP A 11VAL A 12ALA A 18PHE A 45PRO A 73THR A 75TRP A 129 | SAM A 500 |
2Q6O_B_SAMB500 | 2q6o | SAM DB00118(S-Adenosylmethionine) | Salinisporatropica | HYPOTHETICAL PROTEIN | None | 6 | ASP B 11VAL B 12PHE B 45PRO B 73THR B 75TRP B 129 | SAM B 500 |
2UYQ_A_SAMA1311 | 2uyq | SAM DB00118(S-Adenosylmethionine) | Mycobacteriumleprae | HYPOTHETICAL PROTEINML2640 | PF04072(LCM) | 7 | ALA A 110GLY A 112ASP A 132VAL A 136ASP A 161LEU A 162ARG A 163 | SAM A1311 |
2YQZ_A_SAMA301 | 2yqz | SAM DB00118(S-Adenosylmethionine) | Thermusthermophilus | HYPOTHETICAL PROTEINTTHA0223 | PF08241(Methyltransf_11) | 17 | TYR A 12GLU A 45GLY A 47GLY A 49ARG A 52ILE A 53LEU A 67ASP A 68ALA A 69ASP A 70ASP A 94ALA A 95ARG A 96VAL A 111HIS A 112LEU A 113LEU A 116 | SAM A 301 |
2YQZ_B_SAMB401 | 2yqz | SAM DB00118(S-Adenosylmethionine) | Thermusthermophilus | HYPOTHETICAL PROTEINTTHA0223 | None | 17 | TYR B 12GLU B 45GLY B 47GLY B 49ARG B 52ILE B 53LEU B 67ASP B 68ALA B 69ASP B 70ASP B 94ALA B 95VAL B 111HIS B 112LEU B 113LEU B 116VAL B 117 | SAM B 401 |
2YVL_A_SAMA601 | 2yvl | SAM DB00118(S-Adenosylmethionine) | Aquifex aeolicus | HYPOTHETICAL PROTEIN | PF08704(GCD14) | 16 | THR A 72ILE A 74ILE A 75GLY A 99GLY A 101SER A 102ALA A 104LEU A 105GLU A 120ALA A 121VAL A 122ASP A 148PHE A 149ASP A 165VAL A 166TYR A 172 | SAM A 601 |
2YVL_B_SAMB602 | 2yvl | SAM DB00118(S-Adenosylmethionine) | Aquifex aeolicus | HYPOTHETICAL PROTEIN | None | 15 | THR B 72ILE B 74ILE B 75GLY B 99GLY B 101ALA B 104LEU B 105GLU B 120ALA B 121VAL B 122ASP B 148PHE B 149ASP B 165VAL B 166TYR B 172 | SAM B 602 |
2YVL_C_SAMC604 | 2yvl | SAM DB00118(S-Adenosylmethionine) | Aquifex aeolicus | HYPOTHETICAL PROTEIN | None | 16 | THR C 72ILE C 74ILE C 75GLY C 99GLY C 101SER C 102ALA C 104LEU C 105GLU C 120ALA C 121VAL C 122ASP C 148PHE C 149ASP C 165VAL C 166TYR C 172 | SAM C 604 |
2YVL_D_SAMD603 | 2yvl | SAM DB00118(S-Adenosylmethionine) | Aquifex aeolicus | HYPOTHETICAL PROTEIN | None | 14 | THR D 72ILE D 75GLY D 99GLY D 101ALA D 104LEU D 105GLU D 120ALA D 121VAL D 122ASP D 148PHE D 149ASP D 165VAL D 166TYR D 172 | SAM D 603 |