DRUG BINDING INTERFACES MAPPED TO 'HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
5TTG_A_SAMA1301 5ttg SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
PF00856
(SET)
PF05033
(Pre-SET)
12 MET A1136
GLY A1137
TRP A1138
SER A1172
TYR A1173
ASN A1200
HIS A1201
TYR A1242
PHE A1246
PHE A1254
CYS A1256
ARG A1257
SAM A1301
5TTG_B_SAMB1301 5ttg SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
None 11 MET B1136
GLY B1137
TRP B1138
SER B1172
TYR B1173
ASN B1200
HIS B1201
TYR B1242
PHE B1246
PHE B1254
CYS B1256
SAM B1301
5TUZ_A_SAMA3001 5tuz SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
PF00856
(Pre-SET)
PF05033
(SET)
13 MET A1136
GLY A1137
TRP A1138
SER A1172
TYR A1173
ASN A1200
HIS A1201
TYR A1242
PHE A1246
PHE A1254
CYS A1256
ARG A1257
CYS A1258
SAM A3001
5TUZ_B_SAMB3001 5tuz SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
None 12 MET B1136
GLY B1137
TRP B1138
SER B1172
TYR B1173
ASN B1200
HIS B1201
TYR B1242
PHE B1246
PHE B1254
CYS B1256
ARG B1257
SAM B3001
5V9J_A_SAMA1301 5v9j SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
PF00856
(SET)
PF05033
(Pre-SET)
12 MET A1136
GLY A1137
TRP A1138
SER A1172
TYR A1173
ASN A1200
HIS A1201
TYR A1242
PHE A1246
PHE A1254
CYS A1256
ARG A1257
SAM A1301
5V9J_B_SAMB1301 5v9j SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
None 12 MET B1136
GLY B1137
TRP B1138
SER B1172
TYR B1173
ASN B1200
HIS B1201
TYR B1242
PHE B1246
PHE B1254
CYS B1256
ARG B1257
SAM B1301
5VSD_A_SAMA3001 5vsd SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
PF00856
(Pre-SET)
PF05033
(SET)
13 MET A1136
GLY A1137
TRP A1138
SER A1172
TYR A1173
ASN A1200
HIS A1201
TYR A1242
PHE A1246
TRP A1247
PHE A1254
CYS A1256
ARG A1257
SAM A3001
5VSD_B_SAMB3001 5vsd SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
None 12 MET B1136
GLY B1137
TRP B1138
SER B1172
TYR B1173
ASN B1200
HIS B1201
TYR B1242
PHE B1246
PHE B1254
CYS B1256
ARG B1257
SAM B3001
5VSF_A_SAMA3001 5vsf SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
PF00856
(Pre-SET)
PF05033
(SET)
13 MET A1136
GLY A1137
TRP A1138
SER A1172
TYR A1173
ASN A1200
HIS A1201
TYR A1242
PHE A1246
TRP A1247
PHE A1254
CYS A1256
ARG A1257
SAM A3001
5VSF_B_SAMB3001 5vsf SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1
None 12 MET B1136
GLY B1137
TRP B1138
SER B1172
TYR B1173
ASN B1200
HIS B1201
TYR B1242
PHE B1246
PHE B1254
CYS B1256
ARG B1257
SAM B3001