DRUG BINDING INTERFACES MAPPED TO 'HISTONE-LYSINE N-METHYLTRANSFERASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
2R3A_A_SAMA304 | 2r3a | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESUV39H2 | PF00856(Pre-SET)PF05033(SET) | 13 | ARG A 150GLY A 151TRP A 152LYS A 189THR A 192TYR A 193ASN A 219HIS A 220TYR A 261CYS A 287LYS A 288CYS A 289LEU A 298 | SAM A 304 |
3OOI_A_SAMA237 | 3ooi | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-36 AND H4LYSINE-20 SPECIFIC | PF00856(SET) | 13 | ARG A 101GLY A 102TRP A 103ASN A 144TYR A 146ASN A 169HIS A 170TYR A 207ASN A 214CYS A 219LYS A 220CYS A 221LEU A 230 | SAM A 237 |
3OPE_A_SAMA7 | 3ope | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | PROBABLEHISTONE-LYSINEN-METHYLTRANSFERASEASH1L | PF00856(SET) | 12 | LYS A2150GLY A2151TRP A2152ASP A2192TYR A2194ASN A2217HIS A2218TYR A2255GLN A2266CYS A2268LYS A2269ILE A2279 | SAM A 7 |
3OPE_B_SAMB8 | 3ope | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | PROBABLEHISTONE-LYSINEN-METHYLTRANSFERASEASH1L | None | 9 | LYS B2150GLY B2151TRP B2152ASP B2192TYR B2194ASN B2217TYR B2255GLN B2266ILE B2279 | SAM B 8 |
3QOW_A_SAMA417 | 3qow | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASE | PF08123(DOT1) | 15 | TYR A 136GLY A 137GLU A 138THR A 139ASP A 161GLY A 163GLN A 168VAL A 169GLU A 186LYS A 187ALA A 188ASP A 222PHE A 223ASN A 241PHE A 245 | SAM A 417 |
3RQ4_A_SAMA500 | 3rq4 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H2 | PF00856(SET) | 13 | HIS A 32TYR A 114MET A 116GLU A 117GLY A 120SER A 161ASN A 182HIS A 183TYR A 217PHE A 222CYS A 229GLU A 230CYS A 231 | SAM A 500 |
3S8P_A_SAMA500 | 3s8p | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H1 | PF00856(SET) | 15 | HIS A 98TYR A 203SER A 205GLU A 206GLY A 209ALA A 210PHE A 250SER A 251ASN A 272HIS A 273TYR A 307PHE A 312CYS A 319GLU A 320CYS A 321 | SAM A 500 |
3S8P_B_SAMB500 | 3s8p | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H1 | NonePF00856(SET) | 16 | HIS B 98TYR B 203SER B 205GLU B 206GLY B 209ALA B 210PHE B 250SER B 251ARG A 257ASN B 272HIS B 273TYR B 307PHE B 312CYS B 319GLU B 320CYS B 321 | SAM B 500 |
3SMT_A_ACTA1001 | 3smt | ACT DB03166(Aceticacid) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD3 | PF00856(Rubis-subs-bind)PF09273(SET) | 5 | LEU A 340GLY A 341PHE A 387PHE A 428ARG A 432 | ACT A1001 |
3SMT_A_ACTA500 | 3smt | ACT DB03166(Aceticacid) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD3 | PF00856(Rubis-subs-bind)PF09273(SET) | 3 | PHE A 367SER A 377GLN A 379 | ACT A 500 |
3SMT_A_SAMA1000 | 3smt | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD3 | PF00856(Rubis-subs-bind)PF09273(SET) | 10 | ARG A 74GLU A 103PHE A 105PRO A 179THR A 252ARG A 253ASN A 277HIS A 278TYR A 312PHE A 326 | SAM A1000 |
4BUP_A_SAMA500 | 4bup | SAM DB00118(S-Adenosylmethionine) | Mus musculus | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H1 | PF00856(SET) | 14 | HIS A 90TYR A 195SER A 197GLU A 198GLY A 201ALA A 202SER A 243ASN A 264HIS A 265TYR A 299PHE A 304CYS A 311GLU A 312CYS A 313 | SAM A 500 |
4BUP_B_SAMB500 | 4bup | SAM DB00118(S-Adenosylmethionine) | Mus musculus | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H1 | None | 15 | HIS B 90TYR B 195SER B 197GLU B 198GLY B 201ALA B 202PHE B 242SER B 243ASN B 264HIS B 265TYR B 299PHE B 304CYS B 311GLU B 312CYS B 313 | SAM B 500 |
4E47_A_SAMA401 | 4e47 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | PF00856(SET) | 11 | ILE A 223ALA A 226GLY A 227GLU A 228GLY A 264ASN A 265LYS A 294ASN A 296HIS A 297TYR A 335TRP A 352 | SAM A 401 |
4E47_B_SAMB800 | 4e47 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | None | 11 | ILE B 223ALA B 226GLY B 227GLU B 228GLY B 264ASN B 265LYS B 294ASN B 296HIS B 297TYR B 335TRP B 352 | SAM B 800 |
4E47_C_SAMC800 | 4e47 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | None | 11 | ILE C 223ALA C 226GLY C 227GLU C 228GLY C 264ASN C 265LYS C 294ASN C 296HIS C 297TYR C 335TRP C 352 | SAM C 800 |
4E47_D_SAMD800 | 4e47 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | None | 10 | ILE D 223ALA D 226GLU D 228GLY D 264ASN D 265LYS D 294ASN D 296HIS D 297TYR D 335TRP D 352 | SAM D 800 |
4J83_A_SAMA401 | 4j83 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | PF00856(SET) | 11 | ILE A 223ALA A 226GLU A 228GLY A 264ASN A 265LYS A 294ASN A 296HIS A 297TYR A 335TRP A 352GLU A 356 | SAM A 401 |
4JDS_A_SAMA401 | 4jds | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | PF00856(SET) | 11 | ILE A 223ALA A 226GLY A 227GLU A 228GLY A 264ASN A 265LYS A 294ASN A 296HIS A 297TYR A 335TRP A 352 | SAM A 401 |
4JDS_B_SAMB401 | 4jds | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | None | 11 | ILE B 223ALA B 226GLY B 227GLU B 228GLY B 264ASN B 265LYS B 294ASN B 296HIS B 297TYR B 335TRP B 352 | SAM B 401 |
4JDS_C_SAMC401 | 4jds | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | None | 11 | ILE C 223ALA C 226GLY C 227GLU C 228GLY C 264ASN C 265LYS C 294ASN C 296HIS C 297TYR C 335TRP C 352 | SAM C 401 |
4JDS_D_SAMD401 | 4jds | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | None | 11 | ILE D 223ALA D 226GLU D 228GLY D 264ASN D 265LYS D 294ASN D 296HIS D 297TYR D 335TRP D 352GLU D 356 | SAM D 401 |
4JLG_A_SAMA401 | 4jlg | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | PF00856(SET) | 12 | ILE A 223ALA A 226GLY A 227GLU A 228GLY A 264ASN A 265LYS A 294ASN A 296HIS A 297TYR A 335TRP A 352GLU A 356 | SAM A 401 |
4JLG_B_SAMB401 | 4jlg | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | None | 11 | ILE B 223ALA B 226GLU B 228GLY B 264ASN B 265LYS B 294ASN B 296HIS B 297TYR B 335TRP B 352GLU B 356 | SAM B 401 |
4YNM_A_SAMA2304 | 4ynm | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | PF00856(SET) | 13 | LYS A2150GLY A2151TRP A2152ASP A2192HIS A2193TYR A2194ASN A2217HIS A2218TYR A2255GLN A2266CYS A2268LYS A2269ILE A2279 | SAM A2304 |
4YNM_B_SAMB2304 | 4ynm | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | None | 12 | GLY B2151TRP B2152ASP B2192HIS B2193TYR B2194ASN B2217HIS B2218TYR B2255GLN B2266CYS B2268LYS B2269ILE B2279 | SAM B2304 |
4YNP_A_SAMA2304 | 4ynp | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | PF00856(SET) | 14 | LYS A2150GLY A2151TRP A2152ASP A2192HIS A2193TYR A2194ASN A2217HIS A2218TYR A2255GLN A2266CYS A2268LYS A2269CYS A2270ILE A2279 | SAM A2304 |
4YNP_B_SAMB2304 | 4ynp | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | None | 10 | GLY B2151TRP B2152ASP B2192TYR B2194ASN B2217HIS B2218TYR B2255GLN B2266CYS B2268ILE B2279 | SAM B2304 |
4YPA_A_SAMA3004 | 4ypa | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | PF00856(SET) | 12 | LYS A2150GLY A2151TRP A2152ASP A2192TYR A2194ASN A2217HIS A2218TYR A2255GLN A2266CYS A2268LYS A2269ILE A2279 | SAM A3004 |
4YPA_B_SAMB2304 | 4ypa | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | None | 13 | LYS B2150GLY B2151TRP B2152ASP B2192HIS B2193TYR B2194ASN B2217HIS B2218TYR B2255GLN B2266CYS B2268LYS B2269ILE B2279 | SAM B2304 |
4YPA_C_SAMC2304 | 4ypa | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | None | 13 | LYS C2150GLY C2151TRP C2152ASP C2192HIS C2193TYR C2194ASN C2217HIS C2218TYR C2255GLN C2266CYS C2268LYS C2269ILE C2279 | SAM C2304 |
4YPA_D_SAMD2304 | 4ypa | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | None | 13 | LYS D2150GLY D2151TRP D2152ASP D2192HIS D2193TYR D2194ASN D2217HIS D2218TYR D2255GLN D2266CYS D2268LYS D2269ILE D2279 | SAM D2304 |
4YPE_A_SAMA2304 | 4ype | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | PF00856(SET) | 12 | LYS A2150GLY A2151TRP A2152ASP A2192TYR A2194ASN A2217HIS A2218TYR A2255GLN A2266CYS A2268LYS A2269ILE A2279 | SAM A2304 |
4YPE_B_SAMB2304 | 4ype | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | None | 11 | LYS B2150GLY B2151TRP B2152ASP B2192TYR B2194ASN B2217HIS B2218TYR B2255CYS B2268LYS B2269ILE B2279 | SAM B2304 |
4YPU_A_SAMA2304 | 4ypu | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | PF00856(SET) | 12 | LYS A2150GLY A2151TRP A2152ASP A2192HIS A2193TYR A2194ASN A2217HIS A2218TYR A2255GLN A2266CYS A2268LYS A2269 | SAM A2304 |
4YPU_B_SAMB2304 | 4ypu | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | None | 11 | LYS B2150GLY B2151TRP B2152ASP B2192HIS B2193TYR B2194ASN B2217HIS B2218TYR B2255GLN B2266LYS B2269 | SAM B2304 |
5AYF_A_C7HA402 | 5ayf | C7H DB00434(Cyproheptadine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | PF00856(SET) | 5 | TYR A 245GLY A 264TYR A 305TYR A 335GLY A 336 | C7H A 402 |
5AYF_A_SAMA401 | 5ayf | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD7 | PF00856(SET) | 11 | ILE A 223ALA A 226GLY A 227GLU A 228GLY A 264ASN A 265LYS A 294ASN A 296HIS A 297TYR A 335TRP A 352 | SAM A 401 |
5CCL_A_SAMA504 | 5ccl | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESMYD3 | PF00856(SET) | 13 | ARG A 14GLY A 15ASN A 16TYR A 124GLU A 130ASN A 132CYS A 180ASN A 181ASN A 205HIS A 206TYR A 239TYR A 257PHE A 259 | SAM A 504 |
5CCM_A_SAMA504 | 5ccm | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESMYD3 | PF00856(SET) | 12 | ARG A 14GLY A 15ASN A 16TYR A 124GLU A 130ASN A 132ASN A 181ASN A 205HIS A 206TYR A 239TYR A 257PHE A 259 | SAM A 504 |
5CPR_B_SAMB402 | 5cpr | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H1 | PF00856(SET) | 15 | HIS B 98TYR B 203SER B 205GLU B 206GLY B 209ALA B 210PHE B 250SER B 251ASN B 272HIS B 273TYR B 307PHE B 312CYS B 319GLU B 320CYS B 321 | SAM B 402 |
5JHN_A_SAMA1205 | 5jhn | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158LYS A1162PHE A1166CYS A1168 | SAM A1205 |
5JHN_B_SAMB1205 | 5jhn | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 12 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158PHE B1166CYS B1168GLN B1169 | SAM B1205 |
5JIN_A_SAMA1205 | 5jin | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE H3.1 PEPTIDEWITH K9M MUTATION;HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | NonePF00856(SET)PF05033(Pre-SET) | 14 | MET F 9MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158LYS A1162PHE A1166CYS A1168GLN A1169 | SAM A1205 |
5JIN_B_SAMB1205 | 5jin | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 12 | MET B1048TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158LYS B1162PHE B1166CYS B1168GLN B1169 | SAM B1205 |
5JIY_A_SAMA1205 | 5jiy | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158LYS A1162PHE A1166CYS A1168 | SAM A1205 |
5JIY_B_SAMB1205 | 5jiy | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 12 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158LYS B1162PHE B1166CYS B1168 | SAM B1205 |
5JJ0_A_SAMA1205 | 5jj0 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE H3K9M MUTANTPEPTIDE;HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | NonePF00856(Pre-SET)PF05033(SET) | 14 | MET F 9MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158LYS A1162PHE A1166CYS A1168GLN A1169 | SAM A1205 |
5JJ0_B_SAMB1205 | 5jj0 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 13 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158LYS B1162PHE B1166CYS B1168GLN B1169 | SAM B1205 |
5LSU_A_SAMA1304 | 5lsu | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASENSD2 | PF00856(SET) | 14 | ARG A1073GLY A1074TRP A1075HIS A1116TYR A1118ASN A1141HIS A1142TYR A1179ASN A1186THR A1189CYS A1191ARG A1192CYS A1193LEU A1202 | SAM A1304 |
5LSU_B_SAMB1304 | 5lsu | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASENSD2 | None | 15 | ARG B1073GLY B1074TRP B1075HIS B1116PHE B1117TYR B1118ASN B1141HIS B1142TYR B1179ASN B1186THR B1189CYS B1191ARG B1192CYS B1193LEU B1202 | SAM B1304 |
5MVS_A_ADNA401 | 5mvs | ADN DB00640(Adenosine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-79SPECIFIC | PF08123(DOT1) | 7 | GLY A 163GLU A 186LYS A 187ALA A 188ASP A 222PHE A 223ASN A 241 | ADN A 401 |
5MVS_B_ADNB401 | 5mvs | ADN DB00640(Adenosine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-79SPECIFIC | no annotation | 8 | GLY B 163GLU B 186LYS B 187ALA B 188ASP B 222PHE B 223ASN B 241PHE B 245 | ADN B 401 |
5T0K_A_SAMA1304 | 5t0k | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158PHE A1166CYS A1168GLN A1169 | SAM A1304 |
5T0K_B_SAMB1304 | 5t0k | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 13 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158LYS B1162PHE B1166CYS B1168GLN B1169 | SAM B1304 |
5T0M_A_SAMA1205 | 5t0m | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1048TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158LYS A1162PHE A1166CYS A1168GLN A1169 | SAM A1205 |
5T0M_B_SAMB1205 | 5t0m | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 12 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158PHE B1166CYS B1168GLN B1169 | SAM B1205 |
5TQR_B_SAMB8009 | 5tqr | SAM DB00118(S-Adenosylmethionine) | Chaetomiumthermophilum | HISTONE-LYSINEN-METHYLTRANSFERASEEZH2, POLYCOMBPROTEIN SUZ12 | PF00856(VEFS-Box)PF09733(SET) | 10 | LEU B 804CYS B 807GLY B 808TYR B 809VAL B 853TYR B 855TYR B 878ASN B 880HIS B 881TYR B 918 | SAM B8009 |
5TTF_A_SAMA1505 | 5ttf | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | PF00856(Pre-SET)PF05033(SET) | 11 | MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158PHE A1166CYS A1168 | SAM A1505 |
5TTF_B_SAMB1505 | 5ttf | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 12 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158PHE B1166CYS B1168GLN B1169 | SAM B1505 |
5TTF_C_SAMC1505 | 5ttf | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 13 | MET C1048GLY C1049TRP C1050SER C1084TYR C1085ASN C1112HIS C1113TYR C1154PHE C1158TRP C1159PHE C1166CYS C1168GLN C1169 | SAM C1505 |
5TTF_D_SAMD1505 | 5ttf | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 11 | MET D1048GLY D1049TRP D1050SER D1084TYR D1085ASN D1112HIS D1113TYR D1154PHE D1158PHE D1166CYS D1168 | SAM D1505 |
5TTG_A_SAMA1301 | 5ttg | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1136GLY A1137TRP A1138SER A1172TYR A1173ASN A1200HIS A1201TYR A1242PHE A1246PHE A1254CYS A1256ARG A1257 | SAM A1301 |
5TTG_B_SAMB1301 | 5ttg | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | None | 11 | MET B1136GLY B1137TRP B1138SER B1172TYR B1173ASN B1200HIS B1201TYR B1242PHE B1246PHE B1254CYS B1256 | SAM B1301 |
5TUY_A_SAMA1505 | 5tuy | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158PHE A1166CYS A1168GLN A1169 | SAM A1505 |
5TUY_B_SAMB1505 | 5tuy | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 12 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158PHE B1166CYS B1168GLN B1169 | SAM B1505 |
5TUZ_A_SAMA3001 | 5tuz | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | PF00856(Pre-SET)PF05033(SET) | 13 | MET A1136GLY A1137TRP A1138SER A1172TYR A1173ASN A1200HIS A1201TYR A1242PHE A1246PHE A1254CYS A1256ARG A1257CYS A1258 | SAM A3001 |
5TUZ_B_SAMB3001 | 5tuz | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | None | 12 | MET B1136GLY B1137TRP B1138SER B1172TYR B1173ASN B1200HIS B1201TYR B1242PHE B1246PHE B1254CYS B1256ARG B1257 | SAM B3001 |
5UPD_A_SAMA1301 | 5upd | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASENSD3 | PF00856(SET) | 11 | ARG A1155GLY A1156TRP A1157ASN A1198TYR A1200ASN A1223HIS A1224TYR A1261CYS A1273CYS A1275LEU A1284 | SAM A1301 |
5V21_A_SAMA1804 | 5v21 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESETD2 | PF00856(SET) | 12 | LYS A1560GLY A1561TRP A1562HIS A1603TYR A1604TYR A1605ASN A1628HIS A1629TYR A1666GLN A1676CYS A1678LEU A1689 | SAM A1804 |
5V37_A_SAMA504 | 5v37 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESMYD3 | PF00856(SET) | 13 | ARG A 14GLY A 15ASN A 16TYR A 124GLU A 130ASN A 132CYS A 180ASN A 181ASN A 205HIS A 206TYR A 239TYR A 257PHE A 259 | SAM A 504 |
5V9I_A_SAMA1505 | 5v9i | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158PHE A1166CYS A1168GLN A1169 | SAM A1505 |
5V9I_B_SAMB1505 | 5v9i | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 11 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158PHE B1166CYS B1168 | SAM B1505 |
5V9I_C_SAMC1505 | 5v9i | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 11 | MET C1048GLY C1049TRP C1050SER C1084TYR C1085ASN C1112HIS C1113TYR C1154PHE C1158PHE C1166CYS C1168 | SAM C1505 |
5V9I_D_SAMD1505 | 5v9i | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 13 | MET D1048GLY D1049TRP D1050SER D1084TYR D1085ASN D1112HIS D1113TYR D1154PHE D1158TRP D1159PHE D1166CYS D1168GLN D1169 | SAM D1505 |
5V9J_A_SAMA1301 | 5v9j | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1136GLY A1137TRP A1138SER A1172TYR A1173ASN A1200HIS A1201TYR A1242PHE A1246PHE A1254CYS A1256ARG A1257 | SAM A1301 |
5V9J_B_SAMB1301 | 5v9j | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | None | 12 | MET B1136GLY B1137TRP B1138SER B1172TYR B1173ASN B1200HIS B1201TYR B1242PHE B1246PHE B1254CYS B1256ARG B1257 | SAM B1301 |
5VSC_A_SAMA1505 | 5vsc | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158PHE A1166CYS A1168GLN A1169 | SAM A1505 |
5VSC_B_SAMB1505 | 5vsc | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 12 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158PHE B1166CYS B1168GLN B1169 | SAM B1505 |
5VSD_A_SAMA3001 | 5vsd | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | PF00856(Pre-SET)PF05033(SET) | 13 | MET A1136GLY A1137TRP A1138SER A1172TYR A1173ASN A1200HIS A1201TYR A1242PHE A1246TRP A1247PHE A1254CYS A1256ARG A1257 | SAM A3001 |
5VSD_B_SAMB3001 | 5vsd | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | None | 12 | MET B1136GLY B1137TRP B1138SER B1172TYR B1173ASN B1200HIS B1201TYR B1242PHE B1246PHE B1254CYS B1256ARG B1257 | SAM B3001 |
5VSE_A_SAMA1505 | 5vse | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | PF00856(SET)PF05033(Pre-SET) | 12 | MET A1048GLY A1049TRP A1050SER A1084TYR A1085ASN A1112HIS A1113TYR A1154PHE A1158PHE A1166CYS A1168GLN A1169 | SAM A1505 |
5VSE_B_SAMB1505 | 5vse | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 | None | 12 | MET B1048GLY B1049TRP B1050SER B1084TYR B1085ASN B1112HIS B1113TYR B1154PHE B1158PHE B1166CYS B1168GLN B1169 | SAM B1505 |
5VSF_A_SAMA3001 | 5vsf | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | PF00856(Pre-SET)PF05033(SET) | 13 | MET A1136GLY A1137TRP A1138SER A1172TYR A1173ASN A1200HIS A1201TYR A1242PHE A1246TRP A1247PHE A1254CYS A1256ARG A1257 | SAM A3001 |
5VSF_B_SAMB3001 | 5vsf | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 | None | 12 | MET B1136GLY B1137TRP B1138SER B1172TYR B1173ASN B1200HIS B1201TYR B1242PHE B1246PHE B1254CYS B1256ARG B1257 | SAM B3001 |
5WBV_A_SAMA402 | 5wbv | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEKMT5B | PF00856(SET) | 15 | HIS A 98TYR A 203SER A 205GLU A 206GLY A 209ALA A 210PHE A 250SER A 251ASN A 272HIS A 273TYR A 307PHE A 312CYS A 319GLU A 320CYS A 321 | SAM A 402 |
5WBV_B_SAMB402 | 5wbv | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEKMT5B | NonePF00856(SET) | 16 | HIS B 98TYR B 203SER B 205GLU B 206GLY B 209ALA B 210PHE B 250SER B 251ARG A 257ASN B 272HIS B 273TYR B 307PHE B 312CYS B 319GLU B 320CYS B 321 | SAM B 402 |
5YJO_A_SAMA505 | 5yjo | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASESMYD3 | PF00856(SET) | 13 | ARG A 14GLY A 15ASN A 16TYR A 124GLU A 130ASN A 132CYS A 180ASN A 181ASN A 205HIS A 206TYR A 239TYR A 257PHE A 259 | SAM A 505 |
6A5K_A_SAMA805 | 6a5k | SAM DB00118(S-Adenosylmethionine) | Arabidopsisthaliana | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-9 SPECIFICSUVH6 | PF00856(SET)PF02182(SAD_SRA)PF05033(Pre-SET) | 13 | ARG A 626GLY A 627TRP A 628GLU A 663TYR A 664ASN A 717HIS A 718TYR A 759LYS A 776CYS A 778PHE A 779CYS A 780LEU A 789 | SAM A 805 |
6A5M_A_SAMA805 | 6a5m | SAM DB00118(S-Adenosylmethionine) | Arabidopsisthaliana | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-9 SPECIFICSUVH6 | PF00856(SET)PF02182(SAD_SRA)PF05033(Pre-SET) | 13 | ARG A 626GLY A 627TRP A 628GLU A 663TYR A 664ASN A 717HIS A 718TYR A 759LYS A 776CYS A 778PHE A 779CYS A 780LEU A 789 | SAM A 805 |
6AGO_A_SAMA2301 | 6ago | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | PF00856(AWS)PF17907(SET) | 11 | LYS A2150GLY A2151TRP A2152ASP A2192TYR A2194ASN A2217HIS A2218TYR A2255CYS A2268CYS A2270ILE A2279 | SAM A2301 |
6BP4_A_SAMA505 | 6bp4 | SAM DB00118(S-Adenosylmethionine) | Schizosaccharomyces pombe | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-9 SPECIFIC | PF00856(SET)PF05033(Pre-SET) | 15 | LYS A 338GLY A 339TRP A 340ILE A 379THR A 380TYR A 381ARG A 406ASN A 409HIS A 410TYR A 451ARG A 475CYS A 477LYS A 478CYS A 479LEU A 488 | SAM A 505 |
6BP4_B_SAMB505 | 6bp4 | SAM DB00118(S-Adenosylmethionine) | Schizosaccharomyces pombe | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-9 SPECIFIC | None | 13 | LYS B 338GLY B 339TRP B 340ILE B 379TYR B 381ASN B 409HIS B 410TYR B 451ARG B 475CYS B 477CYS B 479LEU B 488GLY B 490 | SAM B 505 |
6CEN_A_SAMA1301 | 6cen | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASENSD3 | PF00856(SET) | 11 | ARG A1155GLY A1156TRP A1157ASN A1198TYR A1200ASN A1223HIS A1224TYR A1261CYS A1273CYS A1275LEU A1284 | SAM A1301 |
6CHG_C_SAMC1101 | 6chg | SAM DB00118(S-Adenosylmethionine) | Homo sapiens;Kluyveromyceslactis | H3;HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-4 SPECIFIC | NonePF00856(SET) | 14 | MET J 4ILE C 867HIS C 868ASN C 869TRP C 870SER C 911SER C 912TYR C 913PHE C 934ASN C 936HIS C 937TYR C 974LEU C 989LEU C 999 | SAM C1101 |
6INE_A_SAMA2304 | 6ine | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEASH1L | PF00856(AWS)PF17907(SET) | 13 | LYS A2150GLY A2151TRP A2152ASP A2192TYR A2194ASN A2217HIS A2218TYR A2255GLN A2266CYS A2268LYS A2269CYS A2270ILE A2279 | SAM A2304 |
6NJ9_K_SAMK500 | 6nj9 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-79SPECIFIC | PF08123(DOT1) | 15 | PRO K 133GLY K 137THR K 139ASP K 161GLY K 163GLY K 165GLN K 168VAL K 169GLU K 186LYS K 187ALA K 188ASP K 222PHE K 223PHE K 239ASN K 241 | SAM K 500 |
6NM4_A_SAMA402 | 6nm4 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEPRDM9 | PF00856(SET) | 7 | ALA A 256GLY A 257LEU A 258GLY A 290TYR A 291ASN A 320CYS A 321 | SAM A 402 |
6NM4_B_SAMB402 | 6nm4 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASEPRDM9 | None | 9 | ILE B 253ALA B 256GLY B 257LEU B 258GLY B 290TYR B 291ASN B 320CYS B 321ARG B 323 | SAM B 402 |
6NQA_K_SAMK500 | 6nqa | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-79SPECIFIC | PF08123(DOT1) | 10 | THR K 139ASP K 161GLY K 163GLY K 165GLN K 168VAL K 169GLU K 186LYS K 187ASN K 241PHE K 245 | SAM K 500 |