DRUG BINDING INTERFACES MAPPED TO 'HISTONE METHYLTRANSFERASE DOT1L'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 1NW3_A_ACTA600 | 1nw3 | ACT DB03166(Aceticacid) | Homo sapiens | HISTONEMETHYLTRANSFERASEDOT1L | PF08123(DOT1) | 5 | LEU A 158VAL A 160TYR A 183ARG A 231THR A 235 | ACT A 600 |
| 1NW3_A_SAMA500 | 1nw3 | SAM DB00118(S-Adenosylmethionine) | Homo sapiens | HISTONEMETHYLTRANSFERASEDOT1L | PF08123(DOT1) | 16 | TYR A 136GLU A 138THR A 139ASP A 161GLY A 163GLN A 168VAL A 169GLU A 186LYS A 187ALA A 188ASP A 222PHE A 223LEU A 224PHE A 239ASN A 241PHE A 245 | SAM A 500 |